Institutional Career Development Core

I.机构职业发展核心（KL 2） 总结/摘要 印第安纳州临床和转化科学研究所（CTSI）在以下方面取得了持续的成就： 通过其职业发展，教育和研究培训（CERT）计划培训KL 2学者。 值得注意的是，CERT已经培训了47名KL 2学者，其中大多数保留在学术职位上（92%）， 平均75%的时间用于研究，晋升为副教授（43%），并获得外部 作为主要研究者获得资金（95%），包括14个R 01，7个其他R级奖项和15 K或同等奖项 职业奖。这47位学者来自29个不同的学科，在 性别（46%女性）和种族/民族（15%代表性不足的少数民族），并很好地分布在 T1到T4的光谱研究。另一个优势是，我们的学者是从 该州的3所主要研究型大学：印第安纳州大学、普渡大学和密歇根大学。 圣母院。这扩大了人才库或学者，教师导师和翻译研究的广度。在这 应用，我们提出了一些新的和创新的培训计划，建立在我们的基础上， 程序.我们设计了KL 2职业发展核心计划的四个具体目标，以最大限度地提高其 对机构临床和转化科学家的培训和职业发展的影响， 区域和国家一级。1)提高我们的基础计划的灵活性和覆盖范围， 研究培训和加速指导独立研究者（K到R）的地位。2)增加培训领域 我们的CERT计划具有独特的优势和差距。关键领域包括执行， 社区参与、监管事务和人口健康。3)在三个新领域开展研究培训： 团队科学、创业精神和体验式学习。4)测试创新的培训方法， 研究和国家合作。我们在所有CTSI中采用“4D”的持续创新周期 活动：设计、演示、复制和传播。我们还计划创新举措， 作为更广泛传播的示范项目。其中包括a）同侪和社区指导 计划，以补充我们已经强大的教师指导计划：B）一个跨CTSA KL 2学者 交流计划; c）为区域CTSA计划服务的I-Corps培训课程; d）国家 协调CTSA-行业在线药物开发培训项目， 与我们的创始行业合作伙伴礼来公司合作。我们正在利用NCATS通用 用新的度量来增强度量。我们正在加强招聘和保留代表性不足的人 少数民族科学家，并提供了一个新的课程，在转化研究伦理。

I. INSTITUTIONAL CAREER DEVELOPMENT CORE (KL2) SUMMARY/ABSTRACT The Indiana Clinical and Translational Sciences Institute (CTSI) has a sustained record of accomplishment of training KL2 Scholars through its Career development, Education and Research Training (CERT) Program. Notably, CERT has trained 47 KL2 Scholars, with most retained in academic positions (92%), spending a median of 75% of their time in research, being promoted to Associate Professor (43%), and obtaining external funding as principal investigators (95%) including 14 R01s, 7 other R-level awards and 15 K or equivalent career awards. These 47 Scholars have come from 29 different disciplines, have been diverse in terms of gender (46% women) and race/ethnicity (15% underrepresented minorities), and are nicely distributed across the spectrum of T1 through T4 research. An additional strength is the fact that our Scholars are recruited from the 3 major research universities in the state: Indiana University, Purdue University, and the University of Notre Dame. This expands the pool or Scholars, faculty mentors, and breadth of translational research. In this application, we propose a number of new and innovative training initiatives that build upon our foundational programs. We designed the four specific aims of the KL2 Career Development Core Program to maximize its impact on the training and career development of clinical and translational scientists at an institutional, regional, and national level. 1) Increase the flexibility and reach of our foundational programs for personalize research training and accelerate mentored-to-independent investigator (K to R) status. 2) Add training in areas where our CERT program has unique strengths as well as gaps. Key domains include implementation, community-engagement, regulatory affairs, and population health. 3) Develop research training in 3 new areas: team science, entrepreneurship, and experiential learning. 4) Test innovative training approaches through research and national collaborations. We employ the continuous innovation cycle of “4Ds” in all of our CTSI activities: Design, Demonstrate, Duplicate, and Disseminate. We also plan innovative initiatives that can serve as model programs for dissemination more broadly. These include a) peer and community mentoring programs to complement our already robust faculty-mentoring program: b) an inter-CTSA KL2 Scholar exchange program; c) an I-Corps training course that serve regional CTSA programs; d) national coordination of an on-line CTSA-industry training program in drug development conducted in collaboration with Lilly, our founding industry partner. We are optimizing program evaluation utilizing NCATS common metrics augmented with novel metrics. We are enhancing recruitment and retention of underrepresent minority scientists, and offering a new course in translational research ethics.