Training in Intellectual and Developmental Disabilities (IDD) Research
智力和发育障碍 (IDD) 研究培训
基本信息
- 批准号:10404641
- 负责人:
- 金额:$ 31.22万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-05-01 至 2025-04-30
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
This application is for a new T32 institutional training program to support postdoctoral research in intellectual and
developmental disabilities (IDDs). The Rose F. Kennedy Center and its program of IDD research has for 50 years been in
the forefront of discoveries in brain development, function and disease. Today, we are in an era of unprecedented
discovery of new genes and gene variants, as well as environmental and related conditions, linked to IDD. At the same
time, we are armed with remarkable advances in modern research tools in neuroscience, genetics and in cell and
molecular biology. Our goal here is to create a vibrant new training program that successfully brings together talented
postdoctoral fellows working with world-class investigators and their laboratories to develop the next generation of
highly motivated and successful IDD-focused research scientists. The four broad objectives of this program are (1) to
provide in-depth research experiences and didactic training in biomedical science for highly talented postdoctoral
fellows in a manner that shapes their lifetime career objectives and at the same time fosters discovery and advancement
of our understanding of, and ability to treat, specific types of IDDs; (2) to build effective cross-discipline communication
between basic research laboratories and IDD-focused clinics, sensitizing our postdoctoral trainees to the perspective of
IDD-focused clinicians and vice versa; (3) to extend this network of cooperation between trainees and their laboratories,
and clinicians and their clinics, to encompass whenever possible the parents/care providers and IDD-affected patients;
and (4) to provide career guidance and professional development to our trainees, with this effort coupled to our goal to
recruit and train members of underrepresented minority groups. To accomplish these important goals, we have assem-
bled a team of 36 highly talented primary trainers selected from our 100-member Rose F. Kennedy IDDRC membership.
These individuals come from 15 basic science and clinical departments and span a host of research approaches to IDD –
from human investigations including iPSC studies, to mouse, fish, fly and worm models of IDDs. In addition, we have
developed a structured training program designed to broaden the trainees IDD-focus well beyond the immediate lab
experience. We have also established a plan of mentoring committees to guide our trainees along with evaluation
processes allowing us to continually monitor and modify our program to ensure we are on track to our stated goals.
Finally, we have engaged our clinical partners working with patients with IDDs and established a strong role for them in
the training program. This program brings our institution’s considerable depth, rigorous scientific approach, and
tradition of innovation to bear on the important study of the cause, treatment and prevention of intellectual disability.
此申请适用于新的 T32 机构培训计划,以支持智力和知识领域的博士后研究
发育障碍(IDD)。罗斯·F·肯尼迪中心及其 IDD 研究项目已有 50 年历史
大脑发育、功能和疾病发现的前沿。今天,我们正处于一个前所未有的时代
发现与 IDD 相关的新基因和基因变异,以及环境和相关条件。同时
随着时间的推移,我们在神经科学、遗传学以及细胞和疾病领域的现代研究工具方面取得了显着的进步。
分子生物学。我们的目标是创建一个充满活力的新培训计划,成功地将才华横溢的人聚集在一起
博士后研究员与世界一流的研究人员及其实验室合作开发下一代
积极主动且成功的专注于 IDD 的研究科学家。该计划的四大目标是 (1)
为高素质博士后提供生物医学方面的深入研究经验和教学培训
以塑造他们一生职业目标并同时促进发现和进步的方式
我们对特定类型 IDD 的理解和治疗能力; (2)建立有效的跨学科沟通
基础研究实验室和以 IDD 为重点的诊所之间的合作,使我们的博士后学员了解
以 IDD 为重点的临床医生,反之亦然; (3) 扩大受训者及其实验室之间的合作网络,
以及临床医生及其诊所,尽可能涵盖父母/护理提供者和受 IDD 影响的患者;
(4) 为我们的学员提供职业指导和专业发展,我们的目标是
招募和培训代表性不足的少数群体的成员。为了实现这些重要目标,我们召集了
组建了一支由 36 名才华横溢的初级培训师组成的团队,他们是从我们的 100 名成员 Rose F. Kennedy IDDRC 会员中挑选出来的。
这些人来自 15 个基础科学和临床部门,涵盖 IDD 的多种研究方法 –
从包括 iPSC 研究在内的人类研究,到 IDD 的小鼠、鱼、苍蝇和蠕虫模型。此外,我们还有
制定了结构化培训计划,旨在将受训者的 IDD 关注范围扩大到直接实验室之外
经验。我们还制定了指导委员会计划来指导我们的学员并进行评估
流程使我们能够持续监控和修改我们的计划,以确保我们能够实现既定目标。
最后,我们让我们的临床合作伙伴与 IDD 患者一起工作,并为他们在这方面发挥了强有力的作用。
培训计划。该项目带来了我们机构的相当深度、严格的科学方法,以及
创新传统对智力障碍的成因、治疗和预防具有重要的研究意义。
项目成果
期刊论文数量(0)
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会议论文数量(0)
专利数量(0)
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{{ truncateString('SOPHIE MOLHOLM', 18)}}的其他基金
SUPPORT FOR THE ROSE F KENNEDY IDDRC P50
支持 ROSE F KENNEDY IDDRC P50
- 批准号:
10669059 - 财政年份:2021
- 资助金额:
$ 31.22万 - 项目类别:
SUPPORT FOR THE ROSE F KENNEDY IDDRC P50
支持 ROSE F KENNEDY IDDRC P50
- 批准号:
10239747 - 财政年份:2021
- 资助金额:
$ 31.22万 - 项目类别:
SUPPORT FOR THE ROSE F KENNEDY IDDRC P50
支持 ROSE F KENNEDY IDDRC P50
- 批准号:
10455674 - 财政年份:2021
- 资助金额:
$ 31.22万 - 项目类别:
Training in Intellectual and Developmental Disabilities (IDD) Research
智力和发育障碍 (IDD) 研究培训
- 批准号:
10636634 - 财政年份:2020
- 资助金额:
$ 31.22万 - 项目类别:
Training in Intellectual and Developmental Disabilities (IDD) Research
智力和发育障碍 (IDD) 研究培训
- 批准号:
10206216 - 财政年份:2020
- 资助金额:
$ 31.22万 - 项目类别:
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