Duke CTSA

杜克大学CTSA

• 批准号: 10406180
• 负责人: JENNIFER S LI
• 金额: $ 978.16万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-02 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10406180
• 关键词: Achievement; Address; Arts; Businesses; Clinical; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Data Science; Discipline of Nursing; Diverse Workforce; Engineering; Ensure; Entrepreneurship; Faculty; Fostering; Funding; Future; Goals; Health; Health Benefit; Health Sciences; Healthcare Systems; Industry; Infrastructure; Institutes; Institution; Methods; Mission; Multi-Institutional Clinical Trial; National Center for Advancing Translational Sciences; Outcome Measure; Patients; Phase; Play; Policy Maker; Population; Process; Public Health; Regulatory Affairs; Research; Research Personnel; Resources; Role; Science; Scientist; Services; Team Process; Training; Translational Research; Translations; Trust; United States; United States National Institutes of Health; Universities; Work; experience; health care delivery; improved; informatics tool; innovation; medical schools; population health; programs; skills

The mission of the Duke Clinical and Translational Science Institute is to catalyze the translation of scientific discoveries into population health benefits through collaborative research. With previous Clinical and Translational Science Award (CTSA) funding, we have successfully developed infrastructure and provided resources to support investigators across the clinical and translational scientific and workforce spectrums. Our achievements have facilitated high-impact discoveries, increased research efficiency, and nurtured a more capable and diverse workforce. We have also ignited a new era of collaborative science at Duke. Several new transdisciplinary programs have been launched, connecting trainees and faculty from our Schools of Medicine, Nursing, Engineering, Business, and Arts and Sciences to enhance translation. In the next phase, Duke proposes to capitalize on new opportunities with three broad initiatives. First, we will optimize clinical and translational science national networks’ methods and processes. Building on Duke’s leading experience coordinating multi-center clinical trials including its national Duke-Vanderbilt NCATS Trial Innovation Center, we will develop methods to optimize ‘local hub,’ ‘hub-to-network’ and ‘network-to-network’ processes for the NCATS Trial Innovation Network. We will also help investigators leverage a number of additional NIH network resources and provide methods to disseminate best practices throughout the CTSA network. Second, we will deepen, nurture, and extend stakeholder collaborations. We will strengthen existing partnerships and foster new ones with stakeholders at both the institutional and investigator levels. Partnerships and programs will expand the breadth and transparency of CTSI activities. We will also support investigators’ greater engagement with a broad range of patients, community groups, clinicians, health care systems, industry, venture capitalists, payers, policy makers, and others. Third, we will catalyze further science integration at Duke. An invigorated professional workforce will facilitate major transdisciplinary science initiatives. A new University-wide coordination infrastructure will further amplify collaboration and bridge science siloes. We will also support teams by improving their skills in team science, studying team processes, and by promoting the recognition of team contributions at our institution. Collectively, these activities will amplify the innovation and impact of our research nationally, regionally, and locally. We will measure outcomes that reflect improvement in the translation of discoveries, use of national best practices, institutional and investigator teamwork, research transparency, and community trust. We will share all best practices with the CTSA network. We believe our achievements will meaningfully enhance the impact of clinical and translational science on health across the United States.

杜克临床和翻译科学研究所的使命是催化科学知识的翻译 通过合作研究发现人口健康益处。与以前的临床和 翻译科学奖(CTSA)资助，我们已经成功地开发了基础设施并提供了 支持临床、转化科学和劳动力领域的研究人员的资源。我们的 成就促进了高影响力的发现，提高了研究效率，并培育了更多 有能力和多样化的劳动力。我们也开启了杜克大学协作科学的新纪元。几个新的 跨学科项目已经启动，将我们医学院的实习生和教职员工联系起来， 护理、工程、商业和文理，以加强翻译。在下一阶段，杜克 建议通过三大举措利用新的机遇。首先，我们将优化临床和医疗服务 翻译科学国家网络的方法和过程。以杜克大学的领先经验为基础 协调多中心临床试验，包括其国家杜克-范德比尔特NCATS试验创新中心， 我们将开发方法来优化本地中心、中心到网络和网络到网络的流程 NCATS试验创新网络。我们还将帮助调查人员利用一些额外的NIH网络 提供各种资源，并提供各种方法，以便在CTSA网络中传播最佳做法。第二，我们将 深化、培育和扩展利益相关者协作。我们将加强现有的伙伴关系，促进 与机构和调查员两个层面的利益攸关方建立新的伙伴关系。合作伙伴关系和计划将 扩大CTSI活动的广度和透明度。我们也将支持调查人员更大的 与广泛的患者、社区团体、临床医生、医疗保健系统、行业、 风险资本家、付款人、政策制定者和其他人。第三，我们将推动进一步的科学整合 杜克。一支精力充沛的专业队伍将促进重大跨学科科学倡议。一种新的 大学范围内的协调基础设施将进一步扩大合作，架起科学竖井的桥梁。我们会 还通过提高团队科学技能，研究团队流程，并通过促进 对我们机构团队贡献的认可。总体而言，这些活动将扩大创新和 我们的研究对国家、地区和地方的影响。我们将衡量反映改进的结果 在成果转化、利用国家最佳做法、机构和调查员团队合作方面， 研究透明度和社区信任。我们将与CTSA网络分享所有最佳做法。我们 我相信我们的成就将有意义地加强临床和翻译科学对健康的影响 在美国各地。