Training in Investigative Dermatology

项目摘要 这T32竞争性更新申请从皮肤病的耶鲁大学提出继续其 在皮肤科学术领域培养未来领导者的良好记录。在32名受训人员中， 在过去15年的资助中得到了T32计划的支持，并且已经完成了他们的 在专业和/或研究培训方面，22人（>60%）目前担任全职学术职务，13人 积极参与实质性基础和/或临床研究，其他9人为全职临床医生- 耶鲁、哈佛、斯坦福大学、西北大学和OSHU的教育工作者。重点将保持在这个方案上 发展医学博士和医学博士/博士皮肤科医生的研究和批判性思维能力，虽然博士 候选人具有重大潜力，使翻译和分子的实质性贡献 皮肤生物学也将被寻求以供考虑。我们还建议在下一个时期利用 根据我们的教师在培养有才华的MD/PhD和PhD博士预科学生的经验， 在全国范围内普及T32培训计划，包括我们自己的。目前确定的培训学院 此次更新由32名在皮肤生物学方面具有广泛专业知识的人员组成， 以前的指导经验。27人是R 01资助的“初级导师/指导员”（8人有教师 19名获委任为皮肤科医生，19名获委任为其他9个科系的医生）。都是成立的 导师和进行尖端的研究，共同涵盖了相当一部分的蜂窝和 分子生物学然而，学员并不局限于这些目前确定的导师作为研究 项目导师;他们强烈鼓励广泛寻找整个大学的导师， 实验室将为他们提供进一步发展和完善研究的最佳机会， 批判性思维能力。作为一个主要的导师资格包括目前的R 01水平的资助， 作为一个成功的指导者，记录了以前的跟踪记录，并得到了该计划执行人员的批准 以马克思因为我们认为这最有利于学员发展智力独立 以及将新的科学技术引入皮肤病学，大量接触杰出的 我们会继续重视本署以外的调查人员。与以往的供资期一样， 学员将有两名导师，一名在皮肤科内部，一名在皮肤科外部。通常，主要导师/PI是 的基础是部门外，皮肤科教师二级顾问作为一个额外的 监督受训者的进展，以帮助确保其职业轨迹保持在正确的轨道上。17皮肤科 教师已被指定为潜在的“二级导师/顾问”，包括医生- 科学家以及那些主要面向临床或尚未完全建立自己的独立 研究项目。4人已被确定为初级教师与证明能力，以获得 经同行审查的供资和在下一个供资周期内成为主要导师的突出潜力。

PROJECT SUMMARY This T32 competitive renewal application from the Yale Department of Dermatology proposes to continue its strong track record of training future leaders in academic dermatology. Of the 32 trainees who were supported by this T32 program during the past 15 years of funding and who have completed their subspecialty and/or research training, 22 (>60%) are currently in full-time academic positions, and 13 are actively engaged in substantive basic and/or clinical investigation, while 9 others are full-time clinician- educators at Yale, Harvard, Stanford, Northwestern, and OSHU. Emphasis will be maintained on this program developing the research and critical thinking skills of MD and MD/PhD dermatologists, although PhD candidates with significant potential to make substantive contributions to translational and molecular cutaneous biology will also be sought out for consideration. We also propose in the next period to capitalize upon the experience of our faculty in training talented MD/PhD and PhD pre-doctoral students who now populate T32 training programs across the country, including our own. The currently identified training faculty for this renewal consists of thirty-two individuals with broad-ranging expertise in cutaneous biology and substantive previous mentoring experience. 27 are R01-funded “Primary Mentors/Preceptors” (8 with faculty appointments in Dermatology and 19 with appointments in nine other departments). All are established mentors and conducting cutting-edge research collectively encompassing a substantial portion of cellular and molecular biology. However, trainees are not restricted to these currently identified mentors as research project preceptors; they are strongly encouraged to look broadly throughout the university for mentors whose laboratories would provide them with the best opportunities to further develop and refine their research and critical thinking skills. Qualifications for being a primary mentor include current R01 level sfunding, a documented previous track record as a successful mentor, and approval by this program's Executive Committee. Because we consider it most conducive to the trainees' development of intellectual independence and to the introduction of new scientific skills into dermatology, substantial exposure to outstanding investigators outside our own department will continue to be emphasized. As in past funding periods, each trainee will have two mentors, one inside and one outside of Dermatology. Typically, the Primary Mentor/PI is based is outside the department, and the Dermatology faculty secondary advisor serves as an additional monitor of the trainee's progress to help ensure that her/his career trajectory stays on course. 17 Dermatology faculty members have been designated as potenital “Secondary Mentors/Advisors” including physician- scientists as well as those that are principally clinically oriented or have yet to fully establish their indendent research programs. 4 individuals have been identified as junior faculty with demonstrated abilities to obtain peer-reviewed funding and outstanding potential to become primary mentors within the next funding cycle.