Biostatistics

项目摘要/摘要 生物统计共享资源(BiostatSR)支持Sidney Kimmel综合癌症 中心(SKCCC)确保研究设计、数据程序和研究数据分析使用最先进的技术 提供准确和可重复的研究结果摘要的方法，包括相关的 不确定性，并帮助SKCCC的研究人员获得同行评审的资金。BiostatSR，成立于 1986年，作为共享资源获得了CCSG的第一笔资金。BiostatSR继续关闭 与SKCCC成员合作，提供研究设计、数据分析、监管和中期研究方面的专业知识 报告(例如，数据安全和监测报告)、手稿写作和开发新的生物统计学 一个项目所需的或使多名SKCCC研究人员受益的方法和研究设计。BiostatSR 还支持创建信息系统，以支持个人或研究计划的努力。 除了被紧密整合到SKCCC的所有计划中外，BiostatSR生物统计学家还 与约翰·霍普金斯医学院其他单位的重要智力联系，如 彭博公共卫生学院。这种多样化的环境为SKCCC调查人员提供了强大的、 基础广泛的生物统计学专业知识。 BiostatSR在当前的赠款周期中雇佣了几名成员，并继续为 对SKCCC的支持。在过去的资金周期中，BiostatSR继续与教职员工一起运作 与SKCCC研究计划和疾病小组保持一致。BiostatSR成员出席定期会议 并可就实验室研究和临床咨询提供咨询 在这些项目中的学习。例如，BiostatSR支持孢子赠款和计划项目赠款 让教职员工参与许多领域的临床前和转化性研究。BiostatSR 成员们在编写案例报告方面提高了与研究协调员的合作水平 表格和特定于议定书的数据库，以确保后续分析将如实提供研究数据。 SKCCC托管共享资源 报告期：2020年1月1日至2020年12月31日

PROJECT SUMMARY/ABSTRACT The Biostatistics Shared Resource (BiostatSR) supports the Sidney Kimmel Comprehensive Cancer Center (SKCCC) to ensure that study designs, data procedures and analyses of study data use state-of-the-art methods that provide an accurate and reproducible summary of the study results, including associated uncertainties, and to help SKCCC researchers garner peer-reviewed funding. The BiostatSR, established in 1986, received its first CCSG funding as a Shared Resource that year. The BiostatSR continues close collaborations with SKCCC Members, providing expertise in study design, data analysis, regulatory and interim reporting (e.g., data safety and monitoring reports), manuscript writing, and development of new biostatistical methods and study designs required by a project or benefiting multiple SKCCC investigators. The BiostatSR also supports creation of information systems to support individual or Research Program efforts. In addition to being strongly integrated into all Programs in the SKCCC, BiostatSR biostatisticians have important intellectual ties to other units at Johns Hopkins Medicine, such as the Department of Biostatistics in the Bloomberg School of Public Health. This diverse environment provides SKCCC investigators with strong, broad-based biostatistical expertise. The BiostatSR hired several members during the current grant cycle and continues to provide outstanding support to the SKCCC. During this past funding cycle, the BiostatSR continued to function with faculty and staff aligned with SKCCC Research Programs and disease groups. BiostatSR members attend regular meetings with their programmatic colleagues and are available for consultation on laboratory investigations and clinical studies in those programs. For example, the BiostatSR supports SPORE grants and Program project grants involving faculty and staff in both preclinical and translational investigations in many areas. BiostatSR members have increased the level of collaboration with study coordinators in the development of case report forms and protocol-specific databases to ensure that subsequent analyses will faithfully present study data. SKCCC Managed Shared Resource Reporting Period: January 1, 2020 to December 31, 2020