Training Program in Biostatistics for Cancer Research

描述(由申请人提供)：这是一份修订后的申请，要求支持以癌症研究为重点的生物统计学培训计划。生物统计学的实践正在发生变化，特别是在癌症研究领域。在过去的二十年里，对细胞生长和发育的分子、生化和遗传成分的发现改变了我们对是什么使正常细胞变成癌细胞的理解。多学科研究团队是抗击癌症的现代方法的核心，生物统计学家越来越多地成为此类团队的一部分。有效的生物统计合作需要在统计学、概率、计算方法以及癌症生物学和医学伦理方面进行广泛的培训。这种团队合作要求统计学家熟悉分子生物学家、病理学家，当然还有临床肿瘤学家，如果合作调查组要成功的话。莱斯大学统计系和德州大学安德森癌症中心生物统计系最近联手开发了一个独特的项目，将各自的优势结合起来，培训癌症研究方面的生物统计学家。生物统计学培训计划的目标是培养新一代生物统计学家，他们将有望在现代癌症研究中与生物医学研究人员并肩工作。我们计划的目标是为学员提供： -统计和概率方面的严格培训 -在M.D.安德森癌症中心从事基础和临床癌症研究的实践经验 -癌症生物学方面的培训和医学研究道德 凭借在贝叶斯方法、决策理论、癌症临床试验、生存分析、统计遗传学、基因组学、生物信息学和统计计算方面的教师专业知识，学员将获得现代癌症研究所需的生物统计学的广泛背景。将莱斯大学和M.D.安德森癌症中心现有的教育资源与实践经验相结合，将使学员在完成培训后能够与生物医学研究人员一起为癌症研究做出基础性贡献。

DESCRIPTION (provided by applicant): This is a revised application for support of a training program in biostatistics with a focus on cancer research. The practice of biostatistics is changing, especially in the area of cancer research. Discoveries over the past two decades into the molecular, biochemical, and genetic components of cell growth and development have changed our understanding of what makes a normal cell become cancerous. Multidisciplinary research teams are at the heart of modern approaches to fighting cancer, and biostatisticians more and more are a part of such teams. Effective biostatistical collaboration requires broad training in statistics, probability, computational methods, as well as cancer biology and medical ethics. Such teamwork requires that the statistician be conversant with molecular biologists, pathologists, and, of course, clinical oncologists if the group of co-investigators is to succeed. The Department of Statistics at Rice University and the Department of Biostatistics at the U.T.M.D. Anderson Cancer Center have recently joined forces to develop a unique program that combines their respective strengths to train biostatisticians in cancer research. The goal of this Training Program in Biostatistics is to prepare a new generation of biostatisticians who will be expected to work side-by-side with biomedical investigators in modern cancer research. The aims of our program are to provide trainees with: -Rigorous training in statistics and probability -Practical experience in basic and clinical cancer research at M.D. Anderson Cancer Center -Training in biological aspects of cancer and medical research ethics With faculty expertise in Bayesian methods, decision theory, cancer clinical trials, survival analysis, statistical genetics, genomics, bioinformatics, and statistical computing, trainees will receive a broad background in biostatistics necessary for modern cancer research. Combining the educational resources available at Rice University and M.D. Anderson Cancer Center with practical experience will enable trainees upon completion to make fundamental contributions to cancer research working alongside biomedical investigators.