Neurocognitive Aging & Analytics Research Education (NAARE)

神经认知老化

• 批准号: 10413811
• 负责人: Meredith Nicole Braskie
• 金额: $ 36.31万
• 依托单位: CALIFORNIA STATE UNIVERSITY FULLERTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10413811
• 关键词: Address; African American population; Aging; Alaska Native; Alzheimer' s disease related dementia; American; Area; Basic Science; Biomedical Research; Brain; Cell physiology; Censuses; Clinical Research; Clinical Trials; Communities; Competence; Computer Analysis; Data; Data Science; Degenerative Disorder; Disease; Economics; Education; Educational Curriculum; Educational workshop; Effectiveness; Enrollment; Ensure; Environmental Risk Factor; Ethnic group; Evaluation; Face; Faculty; Family; Female; Foundations; Funding; Future; GRE Preparation; Generations; Genetic Processes; Genetic Risk; Goals; Health; Health Professional; Impaired cognition; Individual; Investigation; Knowledge; Latino Population; Letters; Mentors; Mentorship; Minority; Molecular; Multimedia; Nerve Degeneration; Neurobiology; Neurocognitive; Neurosciences; Oral; Participant; Physical Function; Population; Population Heterogeneity; Population Research; Process; Program Reviews; Readiness; Research; Research Methodology; Research Personnel; Research Training; Risk Factors; Schools; Science; Scientist; Site Visit; Societies; Statistical Data Interpretation; Students; Talents; Training; Underrepresented Minority; Underrepresented Populations; Underrepresented Students; United States; Universities; Vulnerable Populations; age related; aged; aging brain; aging population; brain health; career; career preparation; cohort; comparative; curriculum development; demographics; disadvantaged student; education research; epidemiology study; ethnic diversity; ethnic health disparity; ethnic minority; evidence base; exhaustion; experience; faculty mentor; graduate school preparation; hands on research; health disparity; health equity; health training; improved; innovation; insight; interest; male; meetings; mental function; minority undergraduate; modifiable risk; neuroimaging; next generation; programs; racial diversity; racial minority; role model; skills; social; success; undergraduate student

PROJECT SUMMARY/ABSTRACT To prepare ourselves for the aging of our increasingly diverse population, we must increase minority representation in the sciences, and train young researchers to understand neurocognitive aging and Alzheimer's disease and related dementias (ADRD), and associated health disparities. CSUF and USC propose an innovative and transformative program entitled, “Neurocognitive Aging & Analytics Research Education (NAARE)” that builds upon our current biomedical research education program on data science and brain health. In the coming decades, the United States and the world will face a rapidly growing aging population, with an insufficient number of experts trained in ADRD research to accommodate this increase. Even though ethnic and racial minorities, including African Americans, Latinos and Native Americans/Alaskans comprise over a third of the U.S. population, they are under-represented in aging studies, leaving us with insufficient knowledge of the genetic and environmental risk factors that contribute to cognitive decline in these populations. The representation of minorities in science and biomedical fields also remains comparatively low. Increasing the number of trained researchers from these underrepresented groups may provide insights into social contextual issues and other factors related to underrepresentation, which may subsequently promote access to these important populations in order to subsequently improve health disparities related to neurocognitive aging in these vulnerable populations. Therefore increasing the number of underrepresented aging researchers continues to be a high national priority. The NAARE program addresses this gap as follows: Aim 1: Provide NAARE scholars hands-on research experiences: Engage three consecutive cohorts (n = 10 per year) of predominantly underrepresented minority undergraduates (50% female) in a 1.5 - year faculty mentored, student-driven research focusing on neurocognitive aging, ADRD, and related health disparities and modifiable risk factors. Aim 2: Develop educational curricula: Traditional and multimedia curricula will be developed for NAARE scholars and also targeted towards a larger diverse student audience (n = 4,500) on the following: basic science behind normal brain aging and ADRD; health disparities, modifiable risk factors and neurocognitive aging; neuroimaging and analytics; and research methods in neurocognitive aging. Aim 3: NAARE Scholar Graduate/Career Preparation: To ensure sustainability and student success, NAARE students will engage in ongoing faculty advising, receive exhaustive graduate school application support via hands-on guidance, and explore first-hand, research intensive universities. In-depth mentored, yet student- owned research experiences that integrate intensive neurocognitive aging and ADRD training, and belonging in the broader scientific community will result in successful future scientists. This program will lead to a greater number of students from underrepresented backgrounds choosing careers in neurocognitive aging and succeeding at them. Our students will become diverse role models for future students for generations to come.

项目摘要/摘要 为了应对日益多样化的人口老龄化，我们必须增加少数族裔 科学上的代表性，并培训年轻的研究人员了解神经认知老化和 阿尔茨海默病和相关痴呆症(ADRD)以及相关的健康差距。CSUF和USC 提出一项创新和变革性的项目，名为《神经认知老化与分析研究》 教育(NAARE)“，它建立在我们当前的数据科学和生物医学研究教育计划的基础上 大脑健康。在接下来的几十年里，美国和世界将面临迅速增长的老龄化 人口数量增加，受过ADRD研究培训的专家数量不足，无法适应这一增长。 即使少数族裔和少数族裔，包括非裔美国人、拉丁美洲人和美洲原住民/阿拉斯加人 他们占美国人口的三分之一以上，在老龄化研究中的代表性不足，这给我们留下了 对导致这些人认知能力下降的遗传和环境风险因素认识不足 人口。少数群体在科学和生物医学领域的代表性也相对较低。 增加来自这些代表性不足群体的训练有素的研究人员的数量可能会提供对 与任职人数不足有关的社会背景问题和其他因素，这可能随后促进 获得这些重要人群，以便随后改善与以下方面有关的健康差距 这些脆弱人群中的神经认知老化。因此，增加任职人数不足的人数 老龄化的研究人员仍然是国家的高度优先事项。NAARE计划解决了这一差距，具体如下： 目标1：为NAARE学者提供实践研究经验：参与三个连续队列(n= 每年10名)占多数的少数民族本科生(50%为女性)在一年半的教职中 有指导的、由学生主导的研究，重点是神经认知老化、ADRD和相关的健康差异 和可改变的风险因素。目标2：开发教育课程：传统和多媒体课程将 是为NAARE学者开发的，也针对更多不同的学生受众(n=4,500)， 以下内容：正常脑老化和ADRD背后的基础科学；健康差异，可改变的风险因素 和神经认知老化；神经成像和分析；以及神经认知老化的研究方法。目标3： 毕业生/职业准备：为了确保可持续性和学生的成功， 学生将参与持续的教师建议，通过以下途径获得详尽的研究生院申请支持 实践指导，探索第一手的研究密集型大学。深入指导，但仍是学生- 拥有将密集的神经认知老化和ADRD训练相结合的研究经验，以及归属感 在更广泛的科学界，将造就成功的未来科学家。这一计划将带来更大的 来自代表性不足背景的学生选择神经认知老化和职业的人数 在他们身上取得成功。我们的学生将成为未来几代学生的不同榜样。