Neurocognitive Aging & Analytics Research Education (NAARE)

神经认知老化

• 批准号: 10088963
• 负责人: Meredith Nicole Braskie
• 金额: $ 37.46万
• 依托单位: CALIFORNIA STATE UNIVERSITY FULLERTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10088963
• 关键词: Address; African American; Aging; Alaska Native; Alzheimer' s disease related dementia; American; Area; Basic Science; Biomedical Research; Brain; Cell physiology; Censuses; Clinical Research; Clinical Trials; Communities; Competence; Computer Analysis; Data; Data Science; Degenerative Disorder; Disease; Economics; Education; Educational Curriculum; Educational workshop; Effectiveness; Enrollment; Ensure; Environmental Risk Factor; Ethnic group; Evaluation; Face; Faculty; Family; Female; Foundations; Funding; Future; GRE Preparation; Generations; Genetic Processes; Genetic Risk; Goals; Health; Health Professional; Impaired cognition; Individual; Investigation; Knowledge; Latino; Letters; Mentors; Mentorship; Minority; Molecular; Multimedia; Nerve Degeneration; Neurobiology; Neurocognitive; Neurosciences; Oral; Participant; Physical Function; Population; Population Heterogeneity; Population Research; Process; Program Reviews; Readiness; Research; Research Methodology; Research Personnel; Research Training; Risk Factors; Schools; Science; Scientist; Site Visit; Societies; Statistical Data Interpretation; Students; Talents; Training; Underrepresented Minority; Underrepresented Populations; Underrepresented Students; United States; Universities; Vulnerable Populations; age related; aged; aging brain; aging population; brain health; career; career preparation; cohort; comparative; curriculum development; demographics; disadvantaged student; education research; epidemiology study; ethnic diversity; ethnic health disparity; ethnic minority population; evidence base; exhaustion; experience; faculty mentor; graduate school preparation; hands on research; health disparity; health equity; health training; improved; innovation; insight; interest; male; meetings; mental function; minority undergraduate; modifiable risk; neuroimaging; next generation; programs; racial diversity; racial minority; role model; skills; social; success; undergraduate student

PROJECT SUMMARY/ABSTRACT To prepare ourselves for the aging of our increasingly diverse population, we must increase minority representation in the sciences, and train young researchers to understand neurocognitive aging and Alzheimer's disease and related dementias (ADRD), and associated health disparities. CSUF and USC propose an innovative and transformative program entitled, “Neurocognitive Aging & Analytics Research Education (NAARE)” that builds upon our current biomedical research education program on data science and brain health. In the coming decades, the United States and the world will face a rapidly growing aging population, with an insufficient number of experts trained in ADRD research to accommodate this increase. Even though ethnic and racial minorities, including African Americans, Latinos and Native Americans/Alaskans comprise over a third of the U.S. population, they are under-represented in aging studies, leaving us with insufficient knowledge of the genetic and environmental risk factors that contribute to cognitive decline in these populations. The representation of minorities in science and biomedical fields also remains comparatively low. Increasing the number of trained researchers from these underrepresented groups may provide insights into social contextual issues and other factors related to underrepresentation, which may subsequently promote access to these important populations in order to subsequently improve health disparities related to neurocognitive aging in these vulnerable populations. Therefore increasing the number of underrepresented aging researchers continues to be a high national priority. The NAARE program addresses this gap as follows: Aim 1: Provide NAARE scholars hands-on research experiences: Engage three consecutive cohorts (n = 10 per year) of predominantly underrepresented minority undergraduates (50% female) in a 1.5 - year faculty mentored, student-driven research focusing on neurocognitive aging, ADRD, and related health disparities and modifiable risk factors. Aim 2: Develop educational curricula: Traditional and multimedia curricula will be developed for NAARE scholars and also targeted towards a larger diverse student audience (n = 4,500) on the following: basic science behind normal brain aging and ADRD; health disparities, modifiable risk factors and neurocognitive aging; neuroimaging and analytics; and research methods in neurocognitive aging. Aim 3: NAARE Scholar Graduate/Career Preparation: To ensure sustainability and student success, NAARE students will engage in ongoing faculty advising, receive exhaustive graduate school application support via hands-on guidance, and explore first-hand, research intensive universities. In-depth mentored, yet student- owned research experiences that integrate intensive neurocognitive aging and ADRD training, and belonging in the broader scientific community will result in successful future scientists. This program will lead to a greater number of students from underrepresented backgrounds choosing careers in neurocognitive aging and succeeding at them. Our students will become diverse role models for future students for generations to come.

项目总结/摘要 为了应对日益多样化的人口老龄化，我们必须增加少数民族人口， 在科学中的代表性，并培养年轻的研究人员了解神经认知老化， 阿尔茨海默病和相关痴呆症（ADRD），以及相关的健康差异。CSUF和USC 我提出了一个创新和变革的计划，题为“神经认知老化与分析研究 教育（NAARE）“，建立在我们目前的生物医学研究教育计划的数据科学和 大脑健康未来几十年，美国和世界都将面临迅速加剧的老龄化 然而，人口的增长速度仍然缓慢，在ADRD研究方面受过培训的专家人数不足，无法适应这一增长。 即使少数民族和种族，包括非洲裔美国人，拉丁美洲人和美洲原住民/阿拉斯加人， 占美国人口的三分之一以上，他们在老龄化研究中的代表性不足，给我们留下了 对导致这些人认知能力下降的遗传和环境风险因素的认识不足， 人口。少数群体在科学和生物医学领域的代表性也相对较低。 增加来自这些代表性不足群体的训练有素的研究人员的数量， 社会背景问题和与任职人数不足有关的其他因素，这些问题可能会 为这些重要人口提供服务，以便随后改善与以下方面有关的健康差距： 神经认知老化。因此，任职人数偏低的人数增加， 老龄化研究人员仍然是国家的一个高度优先事项。NAARE方案以如下方式解决这一差距： 目标1：为NAARE学者提供实践研究经验：参与三个连续的队列（n = 在一年半的教师中，占主导地位的少数民族本科生（50%为女性） 指导，学生驱动的研究，重点是神经认知老化，ADRD和相关的健康差异 和可改变的风险因素。目标2：制定教育课程：传统和多媒体课程将 为NAARE学者开发，也针对更大的多样化学生受众（n = 4，500）， 以下内容：正常大脑老化和ADRD背后的基础科学;健康差异，可改变的风险因素 和神经认知老化;神经影像学和分析学;以及神经认知老化的研究方法。目标三： NAARE奖学金毕业生/职业准备：为了确保可持续发展和学生的成功，NAARE 学生将参与持续的教师咨询，通过以下方式获得详尽的研究生院申请支持： 亲自指导，并探索第一手的研究密集型大学。深入指导，但学生- 拥有整合强化神经认知老化和ADRD培训的研究经验， 在更广泛的科学界将导致成功的未来科学家。该计划将导致更大的 来自代表性不足背景的学生选择神经认知老化的职业的人数， 成功在他们。我们的学生将成为未来几代学生的多元化榜样。