South Africa's new Central Chronic Medicine Dispensing and Distribution program: assessing the clinic, patient, and community impact

南非新的中央慢性药物配发和分配计划:评估诊所、患者和社区的影响

基本信息

  • 批准号:
    10413904
  • 负责人:
  • 金额:
    $ 64.35万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2018
  • 资助国家:
    美国
  • 起止时间:
    2018-07-26 至 2024-05-31
  • 项目状态:
    已结题

项目摘要

Project Summary Achieving the UNAIDS 90-90-90 target by 2020 in sub-Saharan Africa will require innovative solutions to meet the increasing demands placed on public health care facilities. With ART coverage in sub-Saharan Africa hovering around 50%, health systems face the dual challenge of increasing HIV testing and ART enrollment for those not yet in care and continuing to provide treatment to the millions of people already on ART. Community- based ART delivery is a potential strategy for maintaining long-term virologic suppression and retention in HIV care. South Africa’s new Central Chronic Medicine Dispensing and Distribution (CCMDD) program allows clinically stable patients to choose from a list of community pick-up points (e.g., private pharmacies, schools, churches) to access ART and therefore has the potential to offer more convenient services to patients and to decompress health facilities. The current proposal leverages this national policy change to assess the impact of this large scale service delivery intervention at the patient-, clinic-, and community-level over time in the high-density settlement of Umlazi in Durban, South Africa. Using a mixed-methods approach that incorporates the Practical, Robust Implementation and Sustainability Model (PRISM), we will comprehensively evaluate the impact of CCMDD at all 10 public sector clinics in Umlazi through the following specific aims: 1) To prospectively assess patient uptake of CCMDD and patient factors associated with favorable early clinical outcomes for CCMDD enrollees and to compare outcomes with non-enrollees; 2) To evaluate facilitators of and barriers to adoption of CCMDD by patients, clinic staff, and administrators using qualitative methods, and 3) To evaluate virologic suppression over time across all 10 public sector clinics in Umlazi using programmatic electronic health record data. This proposal is motivated by PA-17-182 to better understand system-level interventions using implementation science, which may increase the number of people consistently engaged in HIV care. We have played a major role for over a decade implementing and evaluating interventions along the HIV care continuum in South Africa and are well-positioned to evaluate the impact of this important policy change. Our results will inform clinical leaders and policymakers in high HIV prevalence settings developing community ART delivery systems that will enable life-long therapy for millions of people living with HIV. This research has the potential to change clinical practice throughout sub-Saharan Africa, where innovative and efficient approaches to long-term community-based HIV treatment delivery are urgently needed.
项目总结

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Uptake of community- versus clinic-based antiretroviral therapy dispensing in the Central Chronic Medication Dispensing and Distribution program in South Africa.
  • DOI:
    10.1002/jia2.25877
  • 发表时间:
    2022-01
  • 期刊:
  • 影响因子:
    6
  • 作者:
    Bassett IV;Yan J;Govere S;Khumalo A;Ngobese N;Shazi Z;Nzuza M;Bunda BA;Wara NJ;Stuckwisch A;Zionts D;Dube N;Tshabalala S;Bogart LM;Parker RA
  • 通讯作者:
    Parker RA
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Ingrid Valerie Bassett其他文献

Ingrid Valerie Bassett的其他文献

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{{ truncateString('Ingrid Valerie Bassett', 18)}}的其他基金

Mentoring in patient-oriented research on HIV and global health
指导以患者为中心的艾滋病毒和全球健康研究
  • 批准号:
    9889026
  • 财政年份:
    2019
  • 资助金额:
    $ 64.35万
  • 项目类别:
Mentoring in patient-oriented research on HIV and global health
指导以患者为中心的艾滋病毒和全球健康研究
  • 批准号:
    9790038
  • 财政年份:
    2019
  • 资助金额:
    $ 64.35万
  • 项目类别:
Mentoring in patient-oriented research on HIV and global health
指导以患者为中心的艾滋病毒和全球健康研究
  • 批准号:
    10338169
  • 财政年份:
    2019
  • 资助金额:
    $ 64.35万
  • 项目类别:
Mentoring in patient-oriented research on HIV and global health
指导以患者为中心的艾滋病毒和全球健康研究
  • 批准号:
    10570265
  • 财政年份:
    2019
  • 资助金额:
    $ 64.35万
  • 项目类别:
South Africa's new Central Chronic Medicine Dispensing and Distribution program: assessing the clinic, patient, and community impact
南非新的中央慢性药物配发和分配计划:评估诊所、患者和社区的影响
  • 批准号:
    10194606
  • 财政年份:
    2018
  • 资助金额:
    $ 64.35万
  • 项目类别:
South Africa's new Central Chronic Medicine Dispensing and Distribution program: assessing the clinic, patient, and community impact
南非新的中央慢性药物配发和分配计划:评估诊所、患者和社区的影响
  • 批准号:
    9751392
  • 财政年份:
    2018
  • 资助金额:
    $ 64.35万
  • 项目类别:
What happens after diagnosis: Characterizing long-term HIV care trajectories and mortality in South Africa
诊断后会发生什么:描述南非长期艾滋病毒护理轨迹和死亡率
  • 批准号:
    9140315
  • 财政年份:
    2016
  • 资助金额:
    $ 64.35万
  • 项目类别:
Test and Treat TB: A Proof of Concept Trial in South Africa
测试和治疗结核病:南非的概念验证试验
  • 批准号:
    8739080
  • 财政年份:
    2014
  • 资助金额:
    $ 64.35万
  • 项目类别:
Test and Treat TB: A Proof of Concept Trial in South Africa
测试和治疗结核病:南非的概念验证试验
  • 批准号:
    8887097
  • 财政年份:
    2014
  • 资助金额:
    $ 64.35万
  • 项目类别:
Linkage & Retention: A Randomized Trial to Optimize HIV/TB Care in South Africa
连锁
  • 批准号:
    8462802
  • 财政年份:
    2010
  • 资助金额:
    $ 64.35万
  • 项目类别:

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