Mentoring in patient-oriented research on HIV and global health

指导以患者为中心的艾滋病毒和全球健康研究

• 批准号: 9790038
• 负责人: Ingrid Valerie Bassett
• 金额: $ 13.59万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-08 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9790038
• 关键词: 20 year old; AIDS prevention; Accounting; Acquired Immunodeficiency Syndrome; Address; Adherence; Adopted; Adoption; Africa South of the Sahara; African; Age; Area; Award; Birth; Caring; Chronic; Chronic Care; Church; Client; Clinic; Clinical; Clinical Research; Collaborations; Communicable Diseases; Communities; Congestive; Continuity of Patient Care; Contraceptive methods; Contracts; Country; Data; Data Collection; Development; Diabetes Mellitus; Diagnosis; Educational workshop; Epidemic; Face; Family Planning; Funding; Gender; Goals; Grant; Grant Review; HIV; HIV Infections; HIV diagnosis; HIV/TB; Hair; Health; Health care facility; Health system; Human immunodeficiency virus test; Improve Access; Incidence; Income; Inequality; Infection; Intervention; K-Series Research Career Programs; Longevity; Medicine; Mentors; Mentorship; Methods; Morbidity - disease rate; Nurses; Outcome; Patients; Pharmaceutical Preparations; Pharmacy facility; Physicians; Play; Poverty; Privatization; Provider; Public Health; Public Sector; Recommendation; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Screening procedure; Service delivery model; South Africa; South African; Testing; Time; Training; Travel; United States National Institutes of Health; Ursidae Family; Wait Time; Woman; Work; Writing; age group; aged; antiretroviral therapy; base; career; career development; community based participatory research; community based service; community based treatment; cost; design; diabetes management; experience; global health; health care availability; health care service; high risk; implementation science; improved; innovation; interest; international partnership; medical schools; multidisciplinary; next generation; novel; patient oriented; patient oriented research; pre-exposure prophylaxis; predictive modeling; programs; scale up; screening; transmission process; unintended pregnancy; uptake; virology; young woman

PROJECT SUMMARY The purpose of this K24 mid-career investigator award is to support Dr. Bassett’s mentoring activities and patient-oriented research to improve engagement in HIV care and related conditions globally. Dr. Bassett is a practicing Infectious Disease physician with over 14 years of experience leading clinical research in South Africa related to HIV and TB screening and treatment, for which she received the HIV Medicine Association Research Award in 2015. She has served as a mentor to 15 young investigators, four of whom are currently supported by K awards. Dr. Bassett is deeply committed to continuing and further expanding her mentorship to include trainees from outside of Infectious Disease and those based in sub-Saharan Africa. She has assembled a multi-disciplinary team of advisors who can support her and her trainees’ career development. Dr. Bassett is the Director of the Harvard Center for AIDS Research Developmental Core and its Mentoring Programs, and directs a mock K grant review session three times yearly as well as a grant-writing workshop for the Harvard community. She won the Harvard Medical School Young Mentor Award in 2013 in recognition of her mentoring activities. She proposes an inter-related set of training, mentoring and research objectives that expand the scope of her research into new areas (e.g. HIV prevention, community-based treatment for HIV- associated non-communicable diseases). This K24 would provide Dr. Bassett with: 1) protected time for mentoring early career investigators dedicated to patient-oriented HIV research, including those based in sub- Saharan Africa, 2) a platform for mid-career professional development in mixed methods, implementation science approaches, and expanded mentorship and international partnerships, and 3) an opportunity for new data collection to inform her mentees’ and her own future research programs. Dr. Bassett will leverage her collaborations and partnerships in Umlazi Township, Durban, South Africa, a community with a high HIV burden and one of the highest HIV incidences among young women in the world. The overall goal of the proposed research is to develop innovative, community-based research that addresses fundamental questions about how to improve uptake of HIV prevention and long-term ART provision, as well as how to integrate other critical health needs such as diabetes management and contraception into HIV programs. The proposed high- impact research has direct and immediate application in a high-risk South African township and will support the protected time and resources required for Dr. Bassett to mentor young investigators from both the US and sub- Saharan Africa in patient-oriented research.

项目总结 这一K24职业生涯中期研究员奖的目的是支持巴西特博士的指导活动和 以患者为导向的研究，以改善全球对艾滋病毒护理和相关疾病的参与。巴西特博士是一位 具有14年以上领导南方临床研究经验的传染病执业医师 与艾滋病毒和结核病筛查和治疗有关的非洲，为此她获得了艾滋病毒药物协会 2015年荣获研究奖。她曾担任15名年轻调查人员的导师，其中4人目前 由K奖项支持。巴西特博士坚定地致力于继续并进一步扩大她的导师关系，以 包括来自传染病部门以外的受训人员和撒哈拉以南非洲地区的受训人员。她有 组建了一个多学科的顾问团队，他们可以支持她和她的实习生的职业发展。Dr。 巴西特是哈佛大学艾滋病研究发展核心及其指导中心主任 计划，并指导模拟K赠款审查会议，每年三次，以及为 哈佛社区。她在2013年获得哈佛医学院青年导师奖，以表彰 她的辅导活动。她提出了一套相互关联的培训、指导和研究目标， 将她的研究范围扩大到新的领域(例如艾滋病毒预防、以社区为基础的艾滋病毒治疗-- 相关的非传染性疾病)。这款K24将为巴西特博士提供：1)保护时间 指导致力于以患者为中心的艾滋病毒研究的早期职业调查人员，包括那些以亚 撒哈拉非洲，2)混合方法职业中期专业发展平台，实施 科学方法，扩大导师和国际伙伴关系，以及3)新的机会 收集数据以告知她的被辅导者和她自己未来的研究计划。巴西特医生会利用她 在南非德班Umlazi镇的合作和伙伴关系，这是一个艾滋病毒高感染的社区 这是一种沉重的负担，是世界上年轻女性中艾滋病毒发病率最高的国家之一。该计划的总体目标 建议的研究是开发创新的、以社区为基础的研究，以解决基本问题 关于如何提高艾滋病毒预防和长期抗逆转录病毒药物提供的接受度，以及如何整合其他 将糖尿病管理和避孕等关键健康需求纳入艾滋病毒方案。建议的高- 影响研究直接和立即应用于南非的一个高风险城镇，并将支持 巴西特博士指导来自美国和亚洲的年轻调查人员所需的受保护的时间和资源 撒哈拉非洲以病人为中心的研究。