Acquisition of a Verasonics Vantage 256 Research Ultrasound Platform

收购 Verasonics Vantage 256 研究超声平台

• 批准号: 10415588
• 负责人: Luis Cardoso
• 金额: $ 21.8万
• 依托单位: CITY COLLEGE OF NEW YORK
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2023-08-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10415588
• 关键词: 3-Dimensional; Acoustics; Algorithms; Applications Grants; Architecture; Arterial Fatty Streak; Biology; Biomechanics; Brain; Cities; Clinical; Computer software; Computers; Data; Detection; Faculty; Healthcare; Image; Institution; Memory; New York; Osteoporosis; Research; Research Infrastructure; Resolution; Rupture; Scheme; Signal Transduction; Spinal Cord; Spinal cord injury; System; Thermography; Time; Tissues; Translational Research; Travel; Ultrasonography; Universities; base; bone; cardiogenesis; contrast enhanced; data acquisition; data exchange; elastography; flexibility; fracture risk; imaging modality; imaging platform; imaging system; innovation; instrument; instrumentation; neuroregulation; portability; real-time images; soft tissue; system architecture; tomography; ultrasound; vector

PROJECT SUMMARY This Shared Instrumentation Grant (SIG) proposal is for the acquisition of a state-of-the-art Verasonics Vantage 256 Research Ultrasound Platform. The Verasonics Vantage system is a unique, flexible, open platform for ultrasound innovation across many applications. It provides direct access to raw ultrasound data and the ability to perform high quality real-time imaging. The architecture of the system allows software-based beamforming and sequence control, instead of hardware-based beamforming. Many new acquisition schemes using unconventional transmit beams and transmit/receive sequences can be readily examined using the Vantage system, whereas such approaches typically cannot be implemented using conventional data flow architectures that are based on hardware beamformers. The instrument uses Pixel-Oriented Processing, GPU highly parallelized beamforming, very high frame rate imaging for plane wave transmit beams, data acquisition into local memory limited by acoustic travel time, up to 100,000 frames/second, and an extremely rapid RF signal data transfer to host computer. This research ultrasound platform has been at the heart of the development of several imaging modalities and algorithms now available in clinical ultrasound imaging systems because of its flexibility and portability to hardware-based platforms. There is currently no research ultrasound platform at the City University of New York (CCNY). With the acquisition of the Verasonics Vantage 256, faculty from different departments at our institution (BME, ME, Biology) will gain access to a state-of-the- art imaging platform for translational research in different fields at CCNY. This system will provide us with ultrasound research infrastructure to perform (1) high-resolution real-time imaging with dynamic beamforming, (2) speckle tracking, (3) algorithms for correction of aberration for bone tomography, (4) shear wave elastography in soft tissues, (5) low-intensity stimulation and thermography of brain and spinal cord tissues (6) Detection of microcracks in bone, (7) real-time 3D volume imaging, (8) Contrast Enhanced Ultrasound Imaging, (9) Vector flow imaging, etc. We expect this system will catalyze current research on ultrasound neuromodulation, assessment of osteoporosis and fracture risk, biomechanics of atheroma rupture, spinal cord injury therapy, etc. thus, positively impacting health care in general.

项目概要 该共享仪器补助金 (SIG) 提案旨在收购最先进的 Verasonics Vantage 256 研究超声平台。 Verasonics Vantage 系统是 独特、灵活、开放的平台，可实现跨多种应用的超声创新。它提供 直接访问原始超声数据并能够执行高质量实时成像。这 该系统的架构允许基于软件的波束成形和序列控制，而不是 基于硬件的波束形成。许多使用非常规传输的新采集方案 使用 Vantage 系统可以轻松检查光束和发射/接收序列， 而这种方法通常无法使用传统的数据流来实现 基于硬件波束形成器的架构。该仪器采用面向像素的 处理、GPU 高度并行波束形成、平面波极高帧率成像 发射波束，将数据采集到本地存储器中，受声学传播时间限制，最多 100,000 帧/秒，以及极快的射频信号数据传输到主机。这项研究 超声平台一直是多种成像模式发展的核心 算法现在可用于临床超声成像系统，因为它具有灵活性和 到基于硬件的平台的可移植性。目前尚无研究超声平台 纽约城市大学（CCNY）。购买 Verasonics Vantage 256 后，教师 来自我们机构不同部门（BME、ME、生物学）的学生将获得最先进的- CCNY 不同领域转化研究的艺术成像平台。该系统将提供 我们拥有超声研究基础设施来执行 (1) 高分辨率实时成像 动态波束形成，(2) 散斑跟踪，(3) 骨像差校正算法 断层扫描，(4) 软组织剪切波弹性成像，(5) 低强度刺激和 脑和脊髓组织的热成像 (6) 检测骨骼中的微裂纹，(7) 实时 3D体积成像，（8）对比增强超声成像，（9）矢量流成像等。 预计该系统将促进当前超声神经调节的研究，评估 骨质疏松症和骨折风险、粥样斑块破裂的生物力学、脊髓损伤治疗等。 因此，总体上对医疗保健产生积极影响。