Companion Animal and Animal Food Diagnostic Sample Analysis in Support of FDA Vet-LIRN Activities and Investigation

项目摘要/摘要 位于加州大学马修·J·瑞安兽医医院的微生物学实验室 费城宾夕法尼亚兽医学院目前提供综合微生物学 以及为伴生动物和外来物种提供分子生物学兽医诊断服务。这个 瑞安的微生物学实验室隶属于新博尔顿中心园区的PADLS，这是第一个- 兽医实验室调查和反应网络(VET-LIRN)一级实验室成员。 瑞安的微生物学实验室为来自英联邦的同伴动物兽医提供服务 宾夕法尼亚州和整个美国东部都非常适合现在的兽医- LIRN项目建议书。 瑞安的微生物实验室在分析各种样品和基质类型方面经验丰富， 包括但不限于动物样本、环境样本、水和动物性食品产品。 除了满足当前在大规模爆炸事件中增加实验室能力的需求外 瑞安微生物学实验室涉及同伴动物或动物性食品的疫情或威胁事件 可以通过分子诊断活动进一步加强Vet-LIRN，从而更好地使早期 检测新出现的病原体，促进快速反应，将危害降至最低 最好地保护人类和动物的健康。一些分析被要求作为常规临床护理的一部分 对于生病的动物，而其他的则与常规的尸检有关，无论是意外的还是其他的 无法解释的动物损失或疾病。瑞安的微生物学实验室获得了美国 动物医院协会(AAHA)。AAHA认证是一个严格的评估过程，以确保 兽医医院符合AAHA认证标准，其中包括：病人护理， 诊断成像、实验室、疼痛管理、药学、安全、外科、客户服务、麻醉、 传染病、继续教育、牙科、检查设施、医疗记录、领导力 以及急诊/紧急护理。为了保持认证地位，医院在现场进行全面的 每三年进行一次评估，确保医院符合协会的 强制性标准。获得兽医实验室协会资格的准备工作正在进行中 新开发的瑞安兽医医院实验室的诊断专家(AAVLD)认证 PennVet项目，整合瑞安的所有同伴动物诊断服务。由于不同的 瑞安微生物实验室收到的样品矩阵的性质，特别是分析方法 在分子诊断学领域，正在不断地发展。我们对自己的能力很有信心 由于我们目前的资格和经验，在这个项目中支持兽医-LIRN。

PROJECT SUMMARY/ABSTRACT The Microbiology lab at the Matthew J Ryan Veterinary Hospital, located at the University of Pennsylvania School of Veterinary Medicine in Philadelphia currently offers comprehensive microbiology and molecular biology veterinary diagnostic services for companion animal and exotic species. The Microbiology lab at Ryan is affiliated with the PADLS on the New Bolton Center campus, which is a first- tier laboratory member of the Veterinary Laboratory Investigation and Response Network (Vet-LIRN). The Microbiology lab at Ryan serves companion animal veterinarians from the Commonwealth of Pennsylvania and throughout the Eastern United States making it an excellent fit for the current Vet- LIRN project proposal. The Microbiology lab at Ryan is experienced in the analysis of a variety of sample and matrix types, including but not limited to animal samples, environmental samples, water, and animal food products. In addition to addressing the current need for added laboratory capacity in the event of a large-scale outbreak or threat incident involving companion animals or animal food The Microbiology lab at Ryan can further strengthen the Vet-LIRN through molecular diagnostic activities that better enable early detection of emerging pathogenic agents and facilitate the rapid responses that can minimize harm and best protect both human and animal health. Some analyses are requested as part of routine clinical care for sick animals, while others are associated with routine autopsies, unexpected, or otherwise unexplainable animal losses or illness. The Microbiology lab at Ryan is accredited by the American Animal Hospital Association (AAHA). AAHA accreditation is a rigorous evaluation process to ensure that veterinary hospitals meet the AAHA Standards of Accreditation, which include the areas of: Patient care, diagnostic imaging, laboratory, pain management, pharmacy, safety, surgery, client service, anesthesia, contagious disease, continuing education, dentistry, examination facilities, medical records, leadership and emergency/urgent care. To maintain accredited status, hospitals undergo comprehensive on-site evaluations every three years, which ensures that hospitals are compliant with the Association's mandatory standards. Preparations are in progress to obtain Association of Veterinary Laboratory Diagnosticians (AAVLD) accreditation for the newly developed “Lab at Ryan Veterinary Hospital” which is a PennVet project to consolidate all companion animal diagnostic services at Ryan. Due to the varied nature of the sample matrices received by The Microbiology lab at Ryan, analytical methods, particularly in the area of molecular diagnostics, are constantly under development. We are confident in our ability to support the Vet-LIRN in this project due to our present qualifications and experience.