Companion Animal and Animal Food Diagnostic Sample Analysis in Support of FDA Vet-LIRN Activities and Investigation

项目总结/摘要 马修·J·瑞安兽医医院的微生物学实验室位于密歇根大学， 费城的宾夕法尼亚兽医学院目前提供全面的微生物学 以及伴侣动物和外来物种的分子生物学兽医诊断服务。的 瑞安的微生物学实验室隶属于新博尔顿中心校区的PADLS，这是第一个- 兽医实验室调查和反应网络（Vet-LIRN）的一级实验室成员。 瑞安的微生物学实验室为来自英联邦的伴侣动物兽医提供服务。 宾夕法尼亚州和整个美国东部，使其成为一个非常适合目前的兽医- LIRN项目提案。 Ryan的微生物实验室在分析各种样品和基质类型方面经验丰富， 包括但不限于动物样品、环境样品、水和动物食品。 除了解决目前在发生大规模化学品泄漏时增加实验室能力的需要外， 涉及伴侣动物或动物食品的爆发或威胁事件 可以通过分子诊断活动进一步加强Vet-LIRN， 检测新出现的病原体，并促进快速反应，以尽量减少伤害， 最好的保护人类和动物的健康。一些分析被要求作为常规临床护理的一部分 对于生病的动物，而另一些则与常规尸检，意外或其他有关 无法解释的动物损失或疾病。瑞安的微生物学实验室是由美国认可的 动物医院协会（AAHA）AAHA认证是一个严格的评估过程，以确保 兽医医院符合AAHA认证标准，其中包括：病人护理， 诊断成像、实验室、疼痛管理、药房、安全性、手术、客户服务、麻醉， 传染病，继续教育，牙科，检查设施，医疗记录，领导力 紧急/紧急护理。为了保持认证地位，医院进行全面的现场检查， 每三年进行一次评估，以确保医院遵守协会的 强制性标准。正在筹备获得兽医实验室协会 新开发的“瑞安兽医医院实验室”的诊断师（AAVLD）认证， 一个PennVet项目，以巩固所有伴侣动物诊断服务在瑞安。由于各种 Ryan微生物实验室收到的样品基质的性质，分析方法，特别是 在分子诊断学领域，正在不断地发展。我们对自己的能力充满信心 由于我们目前的资格和经验，我们将在该项目中支持Vet-LIRN。

PROJECT SUMMARY/ABSTRACT The Microbiology lab at the Matthew J Ryan Veterinary Hospital, located at the University of Pennsylvania School of Veterinary Medicine in Philadelphia currently offers comprehensive microbiology and molecular biology veterinary diagnostic services for companion animal and exotic species. The Microbiology lab at Ryan is affiliated with the PADLS on the New Bolton Center campus, which is a first- tier laboratory member of the Veterinary Laboratory Investigation and Response Network (Vet-LIRN). The Microbiology lab at Ryan serves companion animal veterinarians from the Commonwealth of Pennsylvania and throughout the Eastern United States making it an excellent fit for the current Vet- LIRN project proposal. The Microbiology lab at Ryan is experienced in the analysis of a variety of sample and matrix types, including but not limited to animal samples, environmental samples, water, and animal food products. In addition to addressing the current need for added laboratory capacity in the event of a large-scale outbreak or threat incident involving companion animals or animal food The Microbiology lab at Ryan can further strengthen the Vet-LIRN through molecular diagnostic activities that better enable early detection of emerging pathogenic agents and facilitate the rapid responses that can minimize harm and best protect both human and animal health. Some analyses are requested as part of routine clinical care for sick animals, while others are associated with routine autopsies, unexpected, or otherwise unexplainable animal losses or illness. The Microbiology lab at Ryan is accredited by the American Animal Hospital Association (AAHA). AAHA accreditation is a rigorous evaluation process to ensure that veterinary hospitals meet the AAHA Standards of Accreditation, which include the areas of: Patient care, diagnostic imaging, laboratory, pain management, pharmacy, safety, surgery, client service, anesthesia, contagious disease, continuing education, dentistry, examination facilities, medical records, leadership and emergency/urgent care. To maintain accredited status, hospitals undergo comprehensive on-site evaluations every three years, which ensures that hospitals are compliant with the Association's mandatory standards. Preparations are in progress to obtain Association of Veterinary Laboratory Diagnosticians (AAVLD) accreditation for the newly developed “Lab at Ryan Veterinary Hospital” which is a PennVet project to consolidate all companion animal diagnostic services at Ryan. Due to the varied nature of the sample matrices received by The Microbiology lab at Ryan, analytical methods, particularly in the area of molecular diagnostics, are constantly under development. We are confident in our ability to support the Vet-LIRN in this project due to our present qualifications and experience.