权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Automated Nucleic Acid Extraction and Purification System to Build Vet-LIRN Testing Capacity

自动化核酸提取和纯化系统，构建 Vet-LIRN 检测能力

基本信息

批准号：
10820696
负责人：
Stephen Douglas Cole
金额：
$ 2.43万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10820696
关键词：
Automated Nucleic Acid Extraction Purification

项目摘要

There is a public health need for veterinary laboratories to have significant capacity to test animal diagnostic specimens and food/feed samples rapidly and accurately for the presence of important pathogens such as Salmonella, Campylobacter, Listeria and SARS-CoV-2. The FDA Veterinary Laboratory Investigation and Response Network (Vet-LIRN) is a group of veterinary laboratories tasked with protecting the health of humans by being able to rapidly and robustly respond to outbreaks associated with animals and animal products. This equipment-only grant requests support for the purchase of a KingFisher Duo Prime semi-automated nucleic acid extraction system. This equipment will expand the capacity of a Vet-LIRN member laboratory (Ryan Small Animal Hospiital Clinical Microbiology Laboratory at the University of Pennsylvania’s) to perform additional molecular assays for case investigations and enhance their capability to handle additional specimens when surge capacity is potentially needed. It will also the laboratory to more fully engage with proficiency testing and interlaboratory comparison exercises developed by Vet-LIRN. Assays to be developed or implemented using thie equipment by the laboratory will include detection of Salmonella, Campylobacter, Listeria and imipenemase genes from carbapenem-resistant Enterobacterales.

公共卫生需要兽医实验室具有强大的检测能力快速、准确地检测动物诊断样本和食品/饲料样本重要病原体，如沙门氏菌、弯曲杆菌、李斯特氏菌和SARS-CoV-2。美国食品和药物管理局兽医实验室调查与应对网络(VET-LIRN)是一组兽医负责保护人类健康的实验室能够快速而有力地应对与动物和动物产品有关的疫情。这项仅限设备的拨款请求支持购买翠鸟二人组Prime半自动核酸提取系统。该设备将扩大VET-LIRN成员实验室的能力瑞安小动物医院临床微生物学实验室宾夕法尼亚州)为案件调查执行额外的分子分析并增强当可能需要浪涌能力时，他们有能力处理更多的样本。会的同时实验室也要更充分地参与能力测试和实验室间由Vet-LIRN开发的比较练习。将使用以下工具开发或实施的分析实验室的这些设备将包括沙门氏菌、弯曲杆菌、李斯特氏菌的检测以及耐碳青霉烯类肠杆菌亚胺培南基因。