South American Program in HIV Prevention Research (SAPHIR)

项目总结/摘要 有效的艾滋病预防干预措施需要对行为、生物和社会因素进行综合分析 特定文化背景下的传播模式。南美洲艾滋病预防方案 研究（SAPHIR）计划提供来自美国的开发研究人员一个密集的，结构化的计划， 在国际环境中开展关于艾滋病毒综合预防的教育和实际研究培训。 具体目标1。为来自美国的研究人员提供结构化的教育计划， 基于拉丁美洲艾滋病毒预防领域重点研究课题的培训。Saphir 项目学员与来自美国和拉丁美洲的研究导师配对， 一项研究计划，包括现有数据的二次分析和原始研究的设计 研究方案。潜在的研究课题包括行为学、流行病学、临床和实验室问题 在拉丁美洲的具体情况下与艾滋病毒预防有关。 具体目标2。提供一个教学指导和互动研讨会的计划， 在国际环境中采取综合办法预防艾滋病毒。培训计划包括一个 每周举办一系列关于全球艾滋病毒预防关键领域的讲座和研讨会，包括讲座、期刊俱乐部、 研究报告和伦理案例会议。教育计划的概念框架 是基于科学学科的交叉，通过全面预防艾滋病毒的透镜。 具体目标3。建设国际调查员协作网络的能力， 拥有各个科学专业知识领域的研究中心，以制定艾滋病毒的综合方法 拉丁美洲的预防研究。除了对年轻调查员进行实际培训外， 该计划的目的是促进参与研究的机构间合作和能力建设 中心.该计划的毕业生完成以下目标：1）获得知识的基础， 艾滋病毒综合预防的四个核心领域（流行病学、诊断、治疗和预防）; 2） 完成二次数据分析，并准备相应的摘要提交给国际 科学会议; 3）设计一项独立的研究子研究; 4）准备一份研究方案， 对人类受试者进行研究的道德行为的要求，由UCLA办公室定义， 人类研究参与者保护; 5）提交一份供同行评审的资助提案，并收到一份书面申请。 总结陈述;以及6）在当地社区场地和年度研讨会上展示其研究成果 项目学员和导师会议。所有SAPHIR毕业生获得曝光，技能和实践 必要的经验，以获得进入竞争激烈的博士后培训计划，并建立一个 国际艾滋病预防研究学术生涯。

Project Summary/Abstract Effective HIV prevention interventions require the integrated analysis of behavioral, biological, and social transmission patterns within specific cultural contexts. The South American Program in HIV Prevention Research (SAPHIR) program offers developing investigators from the U.S. an intensive, structured program of education and practical research training on comprehensive HIV prevention in an international environment. Specific Aim 1. To provide researchers from the U.S. with a structured program of education and training based on a focused research topic within the field of HIV prevention in Latin America. SAPHIR program trainees are paired with research mentors from the U.S. and Latin America to develop an independent research program incorporating both secondary analysis of existing data and design of an original research study protocol. Potential research topics include behavioral, epidemiological, clinical and laboratory issues related to HIV prevention within specific Latin American contexts. Specific Aim 2. To provide a program of didactic instruction and interactive seminars addressing integrated approaches to HIV prevention in international settings. The training program includes a weekly series of lectures and seminars on key areas of global HIV prevention, including lectures, journal clubs, research presentations, and ethics case conferences. The conceptual framework for the educational program is based on the intersection of scientific disciplines through the lens of comprehensive HIV prevention. Specific Aim 3. To build the capacity of a collaborative network of international investigators and research centers with individual areas of scientific expertise to produce integrated approaches to HIV prevention research in Latin America. In addition to practical training for young investigators, a secondary aim of the program is to promote inter-institutional collaboration and capacity-building for participating research centers. Graduates of the program accomplish the following goals: 1) Acquire a foundation of knowledge in the four core areas of comprehensive HIV prevention (epidemiology, diagnosis, treatment, and prevention); 2) Complete a secondary data analysis and prepare a corresponding abstract for submission to an international scientific conference; 3) Design an independent research sub-study; 4) Prepare a study protocol that meets requirements for the ethical conduct of research with human subjects as defined by the UCLA Office for Human Research Participant Protection; 5) Submit a funding proposal for peer review and receive a written summary statement; and 6) Present results of their research in a local community venue and at an annual conference of program trainees and mentors. All SAPHIR graduates acquire the exposure, skills, and practical experience necessary to gain admission to competitive post-doctoral training programs and to build an academic career in international HIV prevention research.