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中文摘要
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行政核心:摘要 怀孕代表了一种独特的免疫状态,几十年来在很大程度上被忽视了。 免疫学领域。该重债穷国计划旨在支持深入的免疫学表征, 研究怀孕期间的免疫力,以激发下一代疫苗的开发,以保护这种独特的 全球人口中更容易受到感染的部分。行政核心(AC)将发挥 在塑造整体计划的成功方面发挥关键的核心作用,提供行政,结构和临床 支持该计划,使所有努力成为核心,并对合作者进行必要的宣传, 资助者和公私合作伙伴。AC将创建数字和直播平台, 科学信息,将有助于获取样本和数据,将支持获取样本 对于该计划,将支持样本和数据共享的法律的协议,将支持培训/指导,以及 将在财务和项目管理方面发挥作用,以确保整个项目的成功。此外,本发明还提供了一种方法, 协调委员会将协调参与项目评估活动,包括进度报告、现场考察, 根据需要向NIH提供额外的沟通和材料。最后,AC还将用于 保持互动的做法,保持整个团队以及整个重债穷国的凝聚力,确保 所有调查人员都参与了该计划的整体成功,并最终将调查结果转化为 开发真正创新的产品,以重塑怀孕和其他疫苗的开发 免疫抑制人群。
英文摘要
Administrative Core: Summary Pregnancy represents a unique immunological state that has been largely overlooked for decades in the field of immunology. This HIPC program aims to support the deep immunological characterization and investigation of immunity during pregnancy to inspire next generation vaccine development to protect this unique segment of the global population that are more vulnerable to infection. The Administrative Core (AC) will play a critical central role in shaping the success of the overall program offering administrative, structural, and clinical support to the program, nucleating all efforts as well as performing the necessary outreach to collaborators, funders, and public/private partners. The AC will create digital and live platforms for the free exchange of scientific information, will serve to facilitate access to samples and data, will support the acquisition of samples for the program, will support legal agreements for sample and data sharing, will support training/mentorship, and will function in financial and programmatic management to ensure the success of the overall program. In addition, the AC will coordinate participation in program evaluation activities, including progress reports, site visits, and provide additional communication and materials to the NIH as needed. Finally, the AC will also function to maintain interactive practices that maintain cohesion across the team as well as the entire HIPC, ensuring that all investigators are engaged in the overall success of the program and ultimately into translating findings for the development of truly innovative products to reshape vaccine development for pregnancy and other immunosuppressed populations.
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MOMI Data Management
MOMI Data Management
MOMI Administrative Core
Computational Analysis and Modeling Core
  • 批准号:
    10158450
  • 项目类别:
  • 资助金额:
    $17.27万
  • 财政年份:
    2019
  • 负责人:
    DOUGLAS A LAUFFENBURGER
  • 依托单位:
海外基金