MOMI Administrative Core

管理核心：摘要 怀孕代表着一种独特的免疫状态，在过去的几十年里，这种状态在很大程度上被忽视了 免疫学领域。这项重债穷国计划旨在支持深入的免疫学特征和 孕期免疫调查启发下一代疫苗开发保护这一独特的 全球人口中更容易受到感染的一部分。管理核心(AC)将发挥作用 在塑造整个计划的成功方面发挥关键的核心作用，提供管理、结构和临床 支持该方案，开展所有努力，并与合作者进行必要的接触， 资助者和公共/私人合作伙伴。交流中心将创建数字和现场平台，供自由交流 将有助于获取样本和数据的科学信息将支持样本的获取 对于该计划，将支持样本和数据共享的法律协议，将支持培训/指导，以及 将在财务和方案管理方面发挥作用，以确保整个方案的成功。此外, 咨询委员会将协调参与计划评估活动，包括进度报告、现场访问和 根据需要向美国国立卫生研究院提供额外的沟通和材料。最后，空调还将发挥作用 保持整个团队以及整个重债穷国之间保持凝聚力的互动实践，确保 所有调查人员都致力于该项目的全面成功，并最终将调查结果转化为 开发真正创新的产品，以重塑怀孕和其他方面的疫苗开发 免疫抑制人群。

Administrative Core: Summary Pregnancy represents a unique immunological state that has been largely overlooked for decades in the field of immunology. This HIPC program aims to support the deep immunological characterization and investigation of immunity during pregnancy to inspire next generation vaccine development to protect this unique segment of the global population that are more vulnerable to infection. The Administrative Core (AC) will play a critical central role in shaping the success of the overall program offering administrative, structural, and clinical support to the program, nucleating all efforts as well as performing the necessary outreach to collaborators, funders, and public/private partners. The AC will create digital and live platforms for the free exchange of scientific information, will serve to facilitate access to samples and data, will support the acquisition of samples for the program, will support legal agreements for sample and data sharing, will support training/mentorship, and will function in financial and programmatic management to ensure the success of the overall program. In addition, the AC will coordinate participation in program evaluation activities, including progress reports, site visits, and provide additional communication and materials to the NIH as needed. Finally, the AC will also function to maintain interactive practices that maintain cohesion across the team as well as the entire HIPC, ensuring that all investigators are engaged in the overall success of the program and ultimately into translating findings for the development of truly innovative products to reshape vaccine development for pregnancy and other immunosuppressed populations.