Purdue University Molecular Biophysics Training Program

普渡大学分子生物物理学培训项目

• 批准号: 10427257
• 负责人: Yulia N Pushkar
• 金额: $ 31.22万
• 依托单位: PURDUE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10427257
• 关键词: Biophysics; Molecular; Training Programs; Universities

Purdue University Molecular Biophysics Training Program PROJECT SUMMARY In 2015, the Zika virus outbreak emerged as an international public health crisis. In less than a year, scientists at Purdue University published the structure of the mature Zika virus capsid, providing immunologists and drug discovery experts with a sophisticated molecular understanding of how to rationally develop selective anti-viral agents. This remarkably fast transition from the discovery of a novel disease to an atomic model was made possible by a cutting-edge electron microscopy facility, a deep understanding of the theory and application of biophysics, and a diverse team of researchers spearheaded by a well-trained predoctoral student. Successful molecular biophysics training programs will instill upon its trainees many of the same qualities that made this example so effective. To this end, the mission of the Purdue University Molecular Biophysics Training program is to bring together 27 preceptors from six different departments to train an outstanding cohort of graduate students in the underlying theory and practice of cutting-edge biophysical techniques. The program's chief objectives are: (i) to provide enhanced training in the application of molecular biophysics in a rigorous and reproducible way to modern problems in human health and disease, (ii) to foster effective and inclusive teamwork, and (iii) to provide career development opportunities tailored to the goals of individual trainees. To achieve these objectives, selected trainees (6 in each year of the award, typically beginning in their 2nd year of study and supported for up to 2 years) will take a new two-semester gateway class that merges theory with team- based project design and implementation, participate in and help implement an interdepartmental biophysics seminar series that will showcase student-invited external speakers and trainee research on campus, and plan, develop, and implement Purdue's annual biophysics symposium called the Hitchhiker's Guide to the Biomolecular Galaxy. Examples of key activities that support the professional development of these trainees are exercises in teamwork built into program coursework and symposium planning, active development and implementation of detailed individual development plans reviewed and revised annually in collaboration with the mentor, personalized teaching and/or internship opportunities, a grant-writing class tailored to biophysical topics, training in the responsible conduct of research, and participation in the recruitment and retention of underrepresented and/or disabled students. By leveraging Purdue's expertise in Biology Education and self- assessment, the training program and its individual activities will be evaluated annually and refined to ensure that the program is meeting its objectives and the needs of the scientific community.

普渡大学分子生物物理学培训项目 项目概要 2015年，寨卡病毒爆发成为一场国际公共卫生危机。科学家们在不到一年的时间里 普渡大学发表成熟寨卡病毒衣壳结构，为免疫学家和药物提供支持 发现专家对如何合理开发选择性抗病毒药物具有复杂的分子理解 代理。从发现一种新疾病到原子模型的转变非常快 通过尖端的电子显微镜设备、对理论和应用的深刻理解成为可能 生物物理学，以及由训练有素的博士生带头的多元化研究团队。成功的 分子生物物理学培训计划将向学员灌输许多与此相同的品质 例子如此有效。为此，普渡大学分子生物物理学培训计划的使命 汇聚来自6个不同院系的27位导师，培养一批优秀的毕业生 学生学习尖端生物物理技术的基础理论和实践。节目组长 目标是： (i) 以严格和严格的方式提供分子生物物理学应用方面的强化培训 解决现代人类健康和疾病问题的可复制方法，(ii) 促进有效和包容性 团队合作，(iii) 提供适合个人学员目标的职业发展机会。到 为了实现这些目标，选定的受训者（每年获奖 6 名，通常从他们的第二年开始） 学习和支持长达 2 年）将参加一个新的两学期入门课程，该课程将理论与团队相结合 - 基于项目设计和实施，参与并帮助实施跨部门生物物理学 研讨会系列，将展示学生邀请的外部演讲者和校园内的实习生研究，并计划， 制定并实施普渡大学年度生物物理学研讨会，称为“搭便车指南” 生物分子星系。支持这些学员专业发展的关键活动的例子包括 团队合作练习纳入项目课程和研讨会规划、积极发展和 每年与政府合作审查和修订详细的个人发展计划的实施情况 导师、个性化教学和/或实习机会、针对生物物理学主题量身定制的资助写作课程， 负责任地开展研究以及参与招募和保留研究人员的培训 代表性不足和/或残疾学生。通过利用普渡大学在生物教育和自我教育方面的专业知识 评估，培训计划及其各项活动将每年进行评估和完善，以确保 该计划正在实现其目标和科学界的需求。