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Purdue University Molecular Biophysics Training Program

普渡大学分子生物物理学培训项目

基本信息

批准号：
10660976
负责人：
Yulia N Pushkar
金额：
$ 29.45万
依托单位：
PURDUE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-01 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10660976
关键词：
Biophysics Molecular Training Programs Universities

项目摘要

Purdue University Molecular Biophysics Training Program PROJECT SUMMARY In 2015, the Zika virus outbreak emerged as an international public health crisis. In less than a year, scientists at Purdue University published the structure of the mature Zika virus capsid, providing immunologists and drug discovery experts with a sophisticated molecular understanding of how to rationally develop selective anti-viral agents. This remarkably fast transition from the discovery of a novel disease to an atomic model was made possible by a cutting-edge electron microscopy facility, a deep understanding of the theory and application of biophysics, and a diverse team of researchers spearheaded by a well-trained predoctoral student. Successful molecular biophysics training programs will instill upon its trainees many of the same qualities that made this example so effective. To this end, the mission of the Purdue University Molecular Biophysics Training program is to bring together 27 preceptors from six different departments to train an outstanding cohort of graduate students in the underlying theory and practice of cutting-edge biophysical techniques. The program's chief objectives are: (i) to provide enhanced training in the application of molecular biophysics in a rigorous and reproducible way to modern problems in human health and disease, (ii) to foster effective and inclusive teamwork, and (iii) to provide career development opportunities tailored to the goals of individual trainees. To achieve these objectives, selected trainees (6 in each year of the award, typically beginning in their 2nd year of study and supported for up to 2 years) will take a new two-semester gateway class that merges theory with team- based project design and implementation, participate in and help implement an interdepartmental biophysics seminar series that will showcase student-invited external speakers and trainee research on campus, and plan, develop, and implement Purdue's annual biophysics symposium called the Hitchhiker's Guide to the Biomolecular Galaxy. Examples of key activities that support the professional development of these trainees are exercises in teamwork built into program coursework and symposium planning, active development and implementation of detailed individual development plans reviewed and revised annually in collaboration with the mentor, personalized teaching and/or internship opportunities, a grant-writing class tailored to biophysical topics, training in the responsible conduct of research, and participation in the recruitment and retention of underrepresented and/or disabled students. By leveraging Purdue's expertise in Biology Education and self- assessment, the training program and its individual activities will be evaluated annually and refined to ensure that the program is meeting its objectives and the needs of the scientific community.

普渡大学分子生物物理学培训计划项目摘要 2015年，寨卡病毒爆发成为国际公共卫生危机。不到一年，科学家发表了成熟寨卡病毒衣壳的结构，为免疫学家和药物发现专家对如何合理开发选择性抗病毒药物有着复杂的分子理解，剂.从发现一种新的疾病到建立一个原子模型，通过尖端的电子显微镜设备，对电子显微镜的理论和应用的深刻理解，生物物理学，和一个由训练有素的博士前学生带头的多元化的研究团队。成功分子生物物理学培训计划将向受训者灌输许多使这一目标得以实现的相同品质。这样的例子很有效。为此，普渡大学分子生物物理学培训计划的使命是集合来自六个不同系的二十七位导师，学生在基础理论和尖端生物物理技术的实践。节目的主持人目标是：㈠以严格的、（二）以可复制的方式解决人类健康和疾病的现代问题，团队合作，以及（iii）提供适合学员个人目标的职业发展机会。到实现这些目标，选定的学员（每年6名，通常从第二年开始，研究和支持长达2年）将采取一个新的两个学期的网关类，合并理论与团队- 基于项目设计和实施，参与并帮助实施跨部门生物物理学研讨会系列，将展示学生邀请的外部演讲者和实习生在校园里的研究，并计划，开发，并实施普渡大学的年度生物物理学研讨会称为搭便车指南，生物分子星系。支持这些受训人员专业发展的主要活动包括在团队合作的练习内置到程序课程和研讨会规划，积极发展， * 执行每年与联合国开发计划署合作审查和修订的详细的个人发展计划导师、个性化教学和/或实习机会、针对生物物理主题量身定制的资助写作课程，培训负责任地开展研究，并参与招聘和保留代表性不足和/或残疾学生。通过利用普渡大学在生物学教育和自我- 评估，培训计划及其个别活动将每年进行评估和完善，以确保该计划正在满足其目标和科学界的需求。

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Pentanuclear iron complex for water oxidation: spectroscopic analysis of reactive intermediates in solution and catalyst immobilization into the MOF-based photoanode.

DOI：
10.1016/j.jcat.2023.115230
发表时间：
2023-11
期刊：
Journal of catalysis
影响因子：
7.3
作者：
Roman Ezhov;G. Bury;Olga Maximova;Elliot Daniel Grant;Mio Kondo;Shigeyuki Masaoka;Yulia Pushkar
通讯作者：
Roman Ezhov;G. Bury;Olga Maximova;Elliot Daniel Grant;Mio Kondo;Shigeyuki Masaoka;Yulia Pushkar

Development of CryoVR, a virtual reality training system for hands-on cryoEM operations.