University of Hawaii Cancer Center CCSG

摘要 夏威夷大学癌症中心的使命是通过以下方式减轻癌症负担 研究、教育、病人护理和社区推广，强调独特的种族、文化和 夏威夷和太平洋的环境特征。为了完成这一使命，UCC被组织成 两个癌症研究项目：太平洋人口科学(PSP)和癌症生物学(CB)。 每个项目都由两个部分组成，跨越基本机制和病因的研究。 癌症到解决目标和干预措施，以便将发现转化为它所服务的人群。在 其项目，UCC拥有坚实的癌症研究基础，拥有超过1500万美元的同行评议资金， 其中72.5%来自NCI。PSP有28个正式会员，CB有20个正式会员，他们都是 方案内和方案间以及机构间研究的高比例证明了这一点 合作和出版。为了促进研究目标的成功实现，UCC支持五个 共享资源：生物统计学、基因组学和生物信息学、分析生物化学、营养学 支持和新陈代谢学。UCC服务于夏威夷独特的种族多元化集水区 太平洋独特的环境和丰富的自然资源。这推动了UCC对种族多样性和 癌症、研究和社区参与，旨在解决重大的癌症健康问题 在特定人群中，包括夏威夷土著居民之间的差异。研究项目、社区教育、 公共卫生和临床试验干预措施针对集水区的重要癌症和 基本调查包括对药物发现研究环境中的化合物进行评估。一个 建立了独特的、基于社区网络的临床研究企业，通过这些企业 为超过70%的夏威夷人口提供癌症临床试验；这在一定程度上得到了 UCC牵头的三个相互竞争的卫生系统的联合，作为一个支持UCC的合作企业。癌 与关岛大学和其他机构合作，太平洋各地的预防活动取得了重大进展 对癌症控制的影响，并导致形成了UCC领导的跨太平洋癌症伙伴关系 预防。UCC在该地区的重要性体现在其对癌症控制的重大影响上 立法和国家癌症政策。夏威夷大学(UH)已经对UCC进行了大量投资。 随着招聘新主任，UH重申了主任对教员任命的直接权力，并 187,000平方米的事务、中心预算和业务以及空间分配。英国《金融时报》癌症中心大楼。这个 大学、州长和州政府为运营提供了更多的财政支持，并授权 大量招聘教师，以加强现有计划并启动新的计划，通过 UCC的战略规划进程支持其减轻癌症负担的使命。

ABSTRACT The mission of the University of Hawai‘i Cancer Center (UHCC) is to reduce the burden of cancer through research, education, patient care and community outreach with an emphasis on the unique ethnic, cultural and environmental characteristics of Hawai‘i and the Pacific. To accomplish this mission, UHCC is organized into two cancer research programs: Population Sciences in the Pacific (PSP) and Cancer Biology (CB). Programs are each organized with two components spanning the study of basic mechanism and etiologies of cancer to addressing targets and interventions in order to translate discovery to the population it serves. Within its programs, UHCC has a strong foundation of cancer research with over $15 million in peer-reviewed funding, 72.5% of which is from the NCI. PSP has 28 full members and CB has 20 full members who are highly collaborative as evidenced by a high percentage of intra- and inter-programmatic, and inter-institutional, research collaborations and publications. To facilitate successful attainment of research goals, UHCC supports five shared resources: Biostatistics, Genomics and Bioinformatics, Analytical Biochemistry, Nutrition Support, and Metabolomics. UHCC serves a unique ethnically diverse catchment area in Hawai‘i and the Pacific and a unique environment rich in natural resources. This drives UHCC’s focus on ethnic diversity and cancer and research and community engagement directed toward addressing significant cancer health disparities among specific populations, including Native Hawaiians. Research programs, community education, public health and clinical trial interventions are targeted toward cancers of importance in the catchment area and basic investigations include evaluation of compounds from the environment for drug discovery research. A unique, community-network based clinical research enterprise has been established through which UHCC provides access to cancer clinical trials for over 70% of the Hawai‘i population; this is supported in part by a UHCC-led affiliation of three competing health systems as a cooperative venture supporting UHCC. Cancer prevention activities across the Pacific, in collaboration with the University of Guam and others, have had major impact on cancer control and have led to the formation of the UHCC-led Trans-Pacific Partnership for Cancer Prevention. The importance of UHCC in the region is exemplified by its significant impact on cancer control legislation and State cancer policy. The University of Hawai‘i (UH) has made significant investments in UHCC. With the recruitment new Director, UH reaffirmed the Director’s direct authority over faculty appointments and affairs, Center budget and operations, and space allocation in the 187,000 sq. ft. Cancer Center building. The University, Governor and State have provided increased financial support for operations and authorized numerous faculty recruitments to strengthen existing programs and embark on new initiatives informed through the UHCC strategic planning process in support of its mission to reduce the burden of cancer.