Prototyping and Validating Novel Scalable Biomimetic Bioreactors for Low Carbon Cultivated Meat Production

全球粮食系统需要多生产50%的粮食，以维持未来40年不断增长的人口，同时大幅减少与粮食生产和消费相关的温室气体（GHG）排放（社会市场基金会，2020年）。根据气候变化独立委员会的数据，14%的温室气体排放来自世界肉类供应，如果整个价值链不发生变化，到2050年，食品系统的排放量可能会增加30-40% （IPCC,2020）。研究表明，在十年内，养殖肉类将减少17%的温室气体，用于生产鸡肉，减少52%用于生产猪肉，减少92%用于生产牛肉。它还将减少63%的鸡肉、72%的猪肉和95%的牛肉的土地使用（Good Food Institute,2021）。虽然目前的生产成本比同类动物肉类产品高出100-10,000倍，但如果技术和价格适当扩大，可能在2030年之前达到具有竞争力的水平。该行业的进展一直缓慢，但在过去十年中，人造肉已经从2013年第一个价值25万美元的实验室培育汉堡，发展到2023年在美国获得批准并在新加坡餐馆/市场销售的人造鸡。动物替代技术公司是一家位于剑桥大学的B2B工程公司。我们正在为人造肉生产创建一个可扩展的端到端生态系统，包括专业流程、使能技术、软件、硬件和原材料。我们的使命是使可持续粮食的获取民主化，并解决世界上一些最大的可持续性和粮食安全挑战。在这个研发项目中，我们与曼彻斯特大学和剑桥大学的合作旨在开发一种新的生物反应器技术，使肉类生产商能够为市场大规模生产量身定制的养殖肉制品。我们将通过开发我们的新型支架和生物反应器系统来实现这一目标，该系统使养殖肉类生产商能够生产出大量价格合理的肉类产品（从羊肉和猪肉开始），这些产品可扩展，营养丰富，美味可口，适合大众消费，对环境的影响更小，肉类质量更高，当地供应链更强，来源更道德。到目前为止，我们已经从风投和战略投资者那里筹集了300多万英镑，并开发了多项专利/开创性技术，包括水凝胶、细胞系和生物电子传感器。我们的工作获得了多个奖项，AAT参与了4个加速器。我们已经收到来自TechCrunch， Food Navigator， The Spoon等的报道，并致力于解决食品安全和可持续发展的挑战。

Global food systems need to produce 50% more food to sustain growing populations over the next 40years, whilst substantially reducing greenhouse gas (GHG) emissions associated with food production and consumption (Social Market Foundation, 2020). According to the Independent Panel on Climate Change, 14% of total GHG emissions are attributable to the world's meat supply, without changes throughout the value chain, food systems emissions are likely to increase by 30-40% by 2050 (IPCC,2020).Research shows that within a decade Cultivated Meat will reduce 17% GHG for the creation of chicken, reduce by 52% to make pork and reduce by 92% to make beef. It will also reduce land use by 63% for chicken, 72% for pork and 95% for beef (Good Food Institute,2021). While production costs are currently between 100-10,000 times higher than for comparable animal meat products, with the right scale up technologies and prices could reach a competitive point earlier than 2030\. Progress in the industry has been slow but in the last decade cultivated meat has gone form the first lab grown burger costing \>$250,000 in 2013 to cultivated chicken being approved in the USA and sold in Singapore restaurants/markets in 2023\.Animal Alternative Technologies is an engineering B2B company based in the University of Cambridge. We are creating a scalable, end-to-end ecosystem for Cultivated Meat production, including specialist processes, enabling technologies, software, hardware and raw materials. Our mission is to democratise access to sustainable food and tackle some of the world's biggest sustainability and food security challenges. Our collaboration with the University of Manchester and University of Cambridge during this R&D project aims to develop a novel bioreactor technology that enables meat producers to create their own tailored, cultivated meat products for market at scale. We will do this by developing our novel scaffold and bioreactor system which enables cultivated meat producers to produce a plethora of affordable meat products (starting with lamb and pork), that are scalable, nutritious, delicious, for general consumption, with a lower environmental impact, higher quality meat, stronger local supply chains, and ethically sources.To date, we have raised over £3million from VCs and strategic investors, and have developed several patents/pioneering technologies, including hydrogels, cell lines, and bioelectronic sensors. Our work has received multiple awards, and AAT has participated in 4 accelerators. We have received coverage from TechCrunch, Food Navigator, The Spoon, etc., and are driven to tackle food security and sustainability challenges.