UCSF-Kaiser Department of Research Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) Program

摘要 这一竞争性的续期申请是为了支持加州大学旧金山分校弗朗西斯科（UCSF）和凯泽 永久北方加州（KPNC）研究建筑跨学科研究部门 妇女健康职业方案。该方案的目标是： 1.招募一批优秀的、多样化的早期职业妇女健康研究人员; 2.就性和性别对健康和疾病的影响提供有针对性的培训和辅导; 3.以我们现有的计划为基础，针对具有公共卫生重要性的妇女健康主题; 4.加强和整合跨学科研究模式，培养促进联系的研究人员 跨学科和机构，并擅长建立团队科学; 5.促进妇女健康的突出地位，并保留在临床研究中代表性不足的研究人员， 通过指导BIRCWH学者和校友在学术进步和领导力的研究。 我们计划的基本原理是，学者们在女性健康方面的成功职业生涯将改变生物医学 通过持续关注性研究， 性别对健康和疾病的影响。该计划汇集了来自16个国家的导师和顾问， UCSF的部门和中心以及KPNC。该计划的设计强调跨学科的方法， 一系列的女性健康问题。我们将继续该计划在开创性研究方面的举措， 妇女癌症;环境卫生;心理健康、成瘾和认知;传染病; 新陈代谢和骨骼健康;以及整个生命周期的生殖健康。多学科的UCSF/KPNC 咨询委员会与领导层合作监督该计划，包括选择新学者。 我们的计划培养跨学科和研究方法的指导团队。不同的学者和 教师的兴趣，背景，培训，种族/民族和性别方面的领域是一个优先事项。我们 该计划支持三名BIRCWH学者在助理教授水平至少两年，他们 接受量身定制的指导，并参加培训课程、计划研讨会、进度评估， 领导力发展活动，包括校友。一系列职业发展和培训 在UCSF临床和转化科学研究所（CTSI）的机会支持我们的BIRCWH计划。 每个学者的职业发展道路都是根据具体的经验和指导而量身定制的， 最有效地支持向独立过渡。我们的项目评估遵循以下概念框架： 学者职业发展的重要领域，评估学者成果的调查措施， 职业轨迹，科学生产力和BIRCWH计划的有效性长达10年之后。 该计划将继续成为一个独特的资源，使妇女的健康的最前沿， 旧金山弗朗西斯科湾地区和其他地区的进步正在改变我们国家的健康科学。

ABSTRACT This competing renewal application is to support the University of California, San Francisco (UCSF) and Kaiser Permanente Northern California (KPNC) Department of Research Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Program. The program objectives are to: 1. Recruit a superb and diverse group of early-career women's health researchers; 2. Provide tailored training and mentoring on sex and gender influences in health and disease; 3. Build upon our existing program by targeting topics in women's health of public health importance; 4. Strengthen and integrate models of interdisciplinary research to develop researchers who foster linkages across disciplines and institutions and excel in building team science; 5. Promote the prominence of women's health and the retention of investigators underrepresented in clinical research by mentoring BIRCWH scholars and alumni in academic advancement and leadership. The rationale of our program is that scholars' successful careers in women's health will transform biomedical research and ultimately advance women's health in the US through sustained focus on the study of sex and gender influences in health and disease. The program brings together mentors and advisors from 16 of UCSF's departments and centers and KPNC. The program design emphasizes interdisciplinary approaches to a wide range of women's health issues. We will continue the program's initiatives in path-breaking research in women's cancers; environmental health; mental health, addiction, and cognition; infectious diseases; metabolism and bone health; and reproductive health across the lifespan. A multidisciplinary UCSF/KPNC Advisory Committee oversees the program in partnership with leadership, including selection of new scholars. Our program fosters mentoring teams that cross disciplines and research methodologies. Diverse scholars and faculty—in terms of fields of interest, background, training, race/ethnicity, and gender—are a priority. Our program supports three BIRCWH scholars at the Assistant Professor level for at least two years and they receive tailored mentoring and participate in training courses, program seminars, progress assessments, and leadership development activities, including for alumni. An array of career development and training opportunities at the UCSF Clinical and Translational Science Institute (CTSI) support our BIRCWH program. The career development path for each scholar is tailored to the specific experience and mentoring that will most effectively support transition to independence. Our program evaluation follows a conceptual framework of important domains to scholar career development, with survey measures that assess scholar outcomes such as career trajectory, scientific productivity, and BIRCWH program effectiveness for up to 10 years afterwards. The program will continue to be a unique resource to bring women's health to the forefront of promising advances in the San Francisco Bay Area and beyond that are transforming the health sciences for our nation.