UCSF-Kaiser Department of Research Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) Program

摘要 此竞争性续签申请旨在支持加州大学旧金山分校 (UCSF) 和 Kaiser 北加州永久医疗机构 (KPNC) 研究部建设跨学科研究 女性健康职业 (BIRCWH) 计划。该计划的目标是： 1. 招募一批优秀且多元化的早期职业女性健康研究人员； 2. 提供关于性和性别对健康和疾病的影响的定制培训和指导； 3. 在我们现有计划的基础上，针对具有公共卫生重要性的妇女健康主题； 4. 加强和整合跨学科研究模式，培养促进联系的研究人员 跨学科和机构，擅长建立团队科学； 5. 促进对妇女健康的重视并保留临床中代表性不足的研究人员 通过指导 BIRCWH 学者和校友进行学术进步和领导力方面的研究。 我们计划的基本原理是，学者们在女性健康领域的成功职业生涯将改变生物医学领域 通过持续关注性和性别研究，最终促进美国妇女的健康 性别对健康和疾病的影响。该计划汇集了来自 16 个国家的导师和顾问 UCSF 的部门和中心以及 KPNC。课程设计强调跨学科方法 广泛的妇女健康问题。我们将继续该计划的开创性研究举措 女性癌症；环境健康；心理健康、成瘾和认知；传染病； 新陈代谢和骨骼健康；和整个生命周期的生殖健康。多学科 UCSF/KPNC 咨询委员会与领导层合作监督该计划，包括选择新学者。 我们的计划培养跨学科和研究方法的指导团队。不同的学者和 教师——就兴趣领域、背景、培训、种族/民族和性别而言——是优先考虑的。我们的 项目支持三名助理教授级别的 BIRCWH 学者至少两年，他们 接受量身定制的指导并参加培训课程、项目研讨会、进度评估，以及 领导力发展活动，包括针对校友的领导力发展活动。一系列的职业发展和培训 加州大学旧金山分校临床和转化科学研究所 (CTSI) 的机会支持我们的 BIRCWH 项目。 每位学者的职业发展道路都是根据具体的经验和指导量身定制的 最有效地支持向独立过渡。我们的计划评估遵循以下概念框架 学者职业发展的重要领域，通过评估学者成果的调查措施，例如 包括职业轨迹、科学生产力以及 BIRCWH 计划在之后长达 10 年的有效性。 该计划将继续作为一种独特的资源，将妇女的健康带到有希望的最前沿 旧金山湾区及其他地区的进步正在改变我们国家的健康科学。

ABSTRACT This competing renewal application is to support the University of California, San Francisco (UCSF) and Kaiser Permanente Northern California (KPNC) Department of Research Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Program. The program objectives are to: 1. Recruit a superb and diverse group of early-career women's health researchers; 2. Provide tailored training and mentoring on sex and gender influences in health and disease; 3. Build upon our existing program by targeting topics in women's health of public health importance; 4. Strengthen and integrate models of interdisciplinary research to develop researchers who foster linkages across disciplines and institutions and excel in building team science; 5. Promote the prominence of women's health and the retention of investigators underrepresented in clinical research by mentoring BIRCWH scholars and alumni in academic advancement and leadership. The rationale of our program is that scholars' successful careers in women's health will transform biomedical research and ultimately advance women's health in the US through sustained focus on the study of sex and gender influences in health and disease. The program brings together mentors and advisors from 16 of UCSF's departments and centers and KPNC. The program design emphasizes interdisciplinary approaches to a wide range of women's health issues. We will continue the program's initiatives in path-breaking research in women's cancers; environmental health; mental health, addiction, and cognition; infectious diseases; metabolism and bone health; and reproductive health across the lifespan. A multidisciplinary UCSF/KPNC Advisory Committee oversees the program in partnership with leadership, including selection of new scholars. Our program fosters mentoring teams that cross disciplines and research methodologies. Diverse scholars and faculty—in terms of fields of interest, background, training, race/ethnicity, and gender—are a priority. Our program supports three BIRCWH scholars at the Assistant Professor level for at least two years and they receive tailored mentoring and participate in training courses, program seminars, progress assessments, and leadership development activities, including for alumni. An array of career development and training opportunities at the UCSF Clinical and Translational Science Institute (CTSI) support our BIRCWH program. The career development path for each scholar is tailored to the specific experience and mentoring that will most effectively support transition to independence. Our program evaluation follows a conceptual framework of important domains to scholar career development, with survey measures that assess scholar outcomes such as career trajectory, scientific productivity, and BIRCWH program effectiveness for up to 10 years afterwards. The program will continue to be a unique resource to bring women's health to the forefront of promising advances in the San Francisco Bay Area and beyond that are transforming the health sciences for our nation.