Incarceration and Cancer-Related Outcomes (ICRO)

监禁和癌症相关结果 (ICRO)

• 批准号: 10439790
• 负责人: Cary P. Gross
• 金额: $ 27.86万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-13 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10439790
• 关键词: Address; Adult; African American; American; Cancer Burden; Cancer Detection; Clinical Research; Clinical Sciences; Community Healthcare; Complex; Connecticut; Constitutional; Criminal Justice; Data; Data Linkages; Diagnosis; Employment; General Population; Goals; Health; Health system; Healthcare Systems; High-Risk Cancer; Impairment; Imprisonment; Incidence; Individual; Infrastructure; Insurance; Intervention; Interview; Knowledge; Latino; Light; Mainstreaming; Malignant Neoplasms; Measures; Methods; Minority; Mission; Morbidity - disease rate; National Cancer Institute; Outcome; Outcome Study; Perception; Personal Satisfaction; Persons; Population; Public Health; Race; Recording of previous events; Research; Risk; Risk Factors; Social Mobility; Socioeconomic Status; Stage at Diagnosis; System; United States; Vital Statistics; Vulnerable Populations; Work; cancer care; cancer epidemiology; cancer health disparity; cancer risk; care outcomes; correctional system; disparity elimination; disparity reduction; epidemiology study; ethnic minority; ethnic minority population; health care availability; health difference; health disparity; implementation research; implementation science; improved; innovation; low socioeconomic status; men; mortality; novel; novel strategies; prison population; racial and ethnic; racial disparity; racial minority; socioeconomic disparity; socioeconomics; tumor registry

PROJECT SUMMARY The United States has the largest number of individuals incarcerated in the world, the majority of whom are of racial and ethnic minority groups and lower socioeconomic status. Thehigh incarceration rate of minority and poorindividuals makes it especially important tounderstand the epidemiology of cancer among individuals with a history of incarceration and the impact of incarceration on cancer disparities. Individuals with a history of incarceration have higher rates of cancer risk factors, and some work has suggested that incarceration history is associated with a higher risk of cancer mortality. However, prior work has not examined the impact of mass incarceration on access to high quality cancer care, or the degree to which incarceration might contribute to cancer disparities. Until this knowledge gap is addressed, we will not be able to identify effective and durable interventions to mitigate observed disparities in cancer morbidity and mortality. The long-term goal of this application is to reduce disparities in cancer outcomes. The overall objective, which is a next step toward achieving this long-term goal, is to assess the impact of incarceration on cancer outcomes and disparities in cancer detection, quality of treatment, and survival. The central hypothesis of Incarceration and Cancer- Related Outcomes (ICRO) study is that incarceration contributes to racial and socioeconomic disparities in cancer detection, quality of treatment, and mortality. The underlying rationale for this proposed study is that there are currently no ongoing or past cancer epidemiologic studies that enable us to measure the contribution of incarceration on observed racial and socioeconomic disparities. To address this knowledge gap, we will create the first comprehensive linkage of a tumor registry, correctional system data, and state vital statistics supplemented with in-depth interviews, to conduct a sequential explanatory mixed methods study of individuals with cancer. We will describe the burden of cancer among individuals with a history of incarceration at the population level in Connecticut (Aim 1). And among Connecticut residents who are diagnosed with cancer (2005-2014), we will assess the relation between incarceration and cancer mortality; the quality of cancer care; and the degree to which incarceration status moderates the relation between race, socioeconomic status and quality of cancer care and mortality (Aim 2-4). We will then use these data to inform a qualitative study of individual perceptions regarding accessing cancer care in the correctional system and in the immediate post- release period (Aim 5). ICRO will be the first study to shed light on a population level how incarceration may be a substantive contributor to racial and socioeconomic cancer disparities. This study is highly innovative in its application of a mixed methods approach and construction of a novel data linkage to address the important yet understudied question of the contribution of incarceration on observed racial and socioeconomic cancer disparities. Together, the knowledge produced will have a positive impact, as it will result in potential targets for interventions to improve cancer outcomes among the millions of individuals with a history of incarceration.

项目摘要 美国是世界上被监禁人数最多的国家，其中大多数人是 种族和少数民族群体以及较低的社会经济地位。少数民族和少数族裔的高监禁率 贫穷的个体使得了解癌症的流行病学在患有癌症的个体中尤为重要。 监禁的历史和监禁对癌症差异的影响。有以下病史的人 监禁有更高的癌症风险因素，一些工作表明，监禁史 与癌症死亡率的高风险相关。然而，先前的工作没有研究质量的影响， 监禁对获得高质量的癌症护理的影响，或者监禁可能有助于 癌症差异在解决这一知识差距之前，我们将无法确定有效和持久的 采取干预措施，以减少观察到的癌症发病率和死亡率方面的差异。长期目标是 应用是为了减少癌症结果的差异。总体目标是， 为了实现这一长期目标，评估监禁对癌症结果的影响以及 癌症检测、治疗质量和生存率。监禁和癌症的中心假设- 相关结果（ICRO）的研究表明，监禁有助于种族和社会经济差异， 癌症检测、治疗质量和死亡率。这项拟议研究的基本原理是 目前还没有正在进行或过去的癌症流行病学研究，使我们能够衡量的贡献， 种族和社会经济不平等。为了弥补这一知识差距，我们将 创建第一个全面的肿瘤登记，矫正系统数据和国家生命统计数据的链接 辅以深度访谈，对个体进行序贯解释性混合方法研究 得了癌症我们将描述癌症的负担与个人的监禁历史， 康涅狄格州的人口水平（目标1）。在康涅狄格州被诊断出患有癌症的居民中， （2005-2014年），我们将评估监禁与癌症死亡率之间的关系;癌症护理的质量; 以及监禁状况在多大程度上缓和了种族、社会经济地位和 癌症护理质量和死亡率（目标2-4）。然后，我们将使用这些数据为以下定性研究提供信息： 个人对在惩教系统和紧接在后获得癌症护理的看法， 目标5（Aim 5）ICRO将是第一个研究揭示人口水平的监禁可能是如何 是造成种族和社会经济癌症差异的重要因素。这项研究在其创新性 应用混合方法方法并建立新的数据链接，以解决重要的问题， 关于监禁对观察到的种族和社会经济癌症的作用的研究不足的问题 差距。总之，产生的知识将产生积极的影响，因为它将产生潜在的目标， 在数百万有监禁史的人中采取干预措施以改善癌症预后。

项目成果

Medication Access in Prisons and Jails-Some Answers, More Questions.

• DOI: 10.1001/jamahealthforum.2023.0167
• 发表时间: 2023-04-07
• 期刊: JAMA health forum
• 作者: Hawks L;Wang E
• 通讯作者: Wang E

Incarceration and screen-detectable cancer diagnosis among adults in Connecticut.

康涅狄格州成年人的监禁和可筛查癌症诊断。

• DOI: 10.1093/jnci/djad242
• 发表时间: 2024
• 期刊: Journal of the National Cancer Institute
• 作者: Richman,IlanaB;Soulos,PamelaR;Lin,Hsiu-Ju;Aminawung,JeneriusA;Oladeru,OluwadamiloaT;Puglisi,LisaB;Wang,EmilyA;Gross,CaryP
• 通讯作者: Gross,CaryP

Incarceration status and cancer mortality: A population-based study.

• DOI: 10.1371/journal.pone.0274703
• 发表时间: 2022
• 期刊: PloS one
• 影响因子: 3.7

Incarceration and Cancer-Related Outcomes (ICRO) study protocol: using a mixed-methods approach to investigate the role of incarceration on cancer incidence, mortality and quality of care.

• DOI: 10.1136/bmjopen-2021-048863
• 发表时间: 2021-05-25
• 期刊: BMJ open
• 影响因子: 2.9
• 作者: Puglisi L;Halberstam AA;Aminawung J;Gallagher C;Gonsalves L;Schulman-Green D;Lin HJ;Metha R;Mun S;Oladeru OT;Gross C;Wang EA
• 通讯作者: Wang EA

Cancer incidence among incarcerated and formerly incarcerated individuals: A statewide retrospective cohort study.

• DOI: 10.1002/cam4.6162
• 发表时间: 2023-07
• 期刊: Cancer medicine
• 影响因子: 4