The Ohio Valley Node of the Clinical Trials Network
临床试验网络俄亥俄谷节点
基本信息
- 批准号:10441828
- 负责人:
- 金额:$ 3.32万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-07-01 至 2022-02-28
- 项目状态:已结题
- 来源:
- 关键词:AbstinenceAccelerationAcquired Immunodeficiency SyndromeAddressAdherenceAdolescentAdultAffectAfrican AmericanAgeAlcoholsAnxietyAnxiety DisordersBackBehaviorBehavior TherapyBehavioral ModelBenzodiazepinesBiographyBlack, Indigenous, People of ColorBudgetsBupropionCalibrationCategoriesCaucasiansCessation of lifeCharacteristicsChildClinicClinicalClinical DataClinical TreatmentClinical TrialsClinical Trials NetworkCocaineCocaine DependenceCocaine UsersCognitive TherapyCollectionColorCommunitiesCounselingDataData AggregationData AnalysesData CollectionData PoolingData SetDatabasesDeath RateDiagnosticDiseaseDrug abuseEducationEffect Modifiers (Epidemiology)EffectivenessEmploymentEnrollmentEthnic OriginEthnic groupEvaluationEvidence based treatmentFactor AnalysisFentanylFrequenciesFundingGender IdentityGlassGoalsGrantGrowthHarm ReductionHealthHealth Services AccessibilityHealth behaviorHeroinHispanicsIncentivesIndividualInstitutionInstitutional Review BoardsInterceptInterest GroupInternationalInterventionJordanKnowledgeLatinxLearningLife StyleLinkLiteratureLong-Term EffectsMeasurementMeasuresMedicalMeta-AnalysisMethamphetamineMethodologyMethodsMinorityModalityModelingMotivationNational Institute of Drug AbuseNational Institute of Mental HealthNational Institute on Alcohol Abuse and AlcoholismNeighborhoodsOhioOpioidOutcomeOutpatientsPaperParticipantPatient Self-ReportPatient-Focused OutcomesPatientsPerceptionPharmaceutical PreparationsPharmacological TreatmentPharmacotherapyPopulationPositioning AttributePost-Traumatic Stress DisordersPrivatizationProcessPropertyProtocols documentationProviderPsychiatric therapeutic procedurePsychiatristPsychiatryPsychosocial FactorPublic HealthPublicationsPublishingRaceRandomizedRandomized Clinical TrialsReadinessReportingResearchResearch DesignResearch MethodologyResearch PersonnelResearch Project GrantsResourcesReview LiteratureRiskRoleSafetySamplingSelf EfficacySeveritiesSiteSmokerSocial ConditionsSocioeconomic FactorsSourceStressSubgroupSubstance AddictionSubstance Use DisorderSubstance abuse problemSystemTestingTherapeuticTimeTime trendTimeLineTobacco Use DisorderToxicologyTrainingTraumaTreatment EffectivenessTreatment EfficacyTreatment outcomeUnderrepresented MinorityUnderrepresented PopulationsUnited StatesUrineValidationVariantVeinsVital StatisticsWeightWomanWorkWritingactive methodaddictionalcohol abuse therapybaseblack subgroupcareerchildhood anxietyclinically significantcocaine overdosecocaine usecomorbiditycomparative effectivenesscomparative efficacycompare effectivenesscontextual factorscookingcultural competencedata harmonizationdesigndual diagnosiseducation researcheffectiveness evaluationefficacy evaluationethnic differenceethnic diversityevidence baseexperiencefollow-uphealth care qualityhealth differencehealth disparityimprovedindividual patientinnovationinterestmarijuana usemeetingsmenmen&aposs groupmethadone clinic/centermotivational enhancement therapymulti-racialmultidisciplinarymultilevel analysisnicotine patchnovelopioid epidemicopioid mortalityopioid useoverdose deathpatient subsetspregnantprimary outcomeprogramspsychosocialpsychostimulantracial and ethnicracial and ethnic disparitiesracismrate of changeresponserural African Americanscience educationscreening, brief intervention, referral, and treatmentsecondary analysissecondary outcomesexsocialsocial factorssocial health determinantssociodemographic factorssociodemographicsstatisticsstructured datasubstance abuse treatmentsubstance usesubstance use treatmentsubstance usersymposiumsynergismsynthetic opioidtheoriestreatment adherencetreatment armtreatment effecttreatment programtreatment trialyoung adultyoung man
项目摘要
Using Integrative Data Analysis to Examine the Impact of Psychosocial Treatments for
Black Cocaine Users Enrolled in the NIDA Drug Abuse Treatment Clinical Trials Network
(CTN)
Specific Aims
Recent reports reveal that the acceleration of opioid-involved overdose deaths for Black people
now outpaces that of White people.1 This increase is attributable to the presence of synthetic
opioids (fentanyl) in the cocaine supply in approximately one third of opioid overdose deaths.
The limited body of work available suggests that treatment effectiveness may vary across racial-
ethnic groups. Yet, only a subset of these studies have specifically looked at cocaine use. The
CTN provides a unique but underexplored collection of studies that can improve our knowledge
on effective psychosocial treatments for Black people who use cocaine. The proposed study will
combine data from 7 CTN treatment studies (total N = 1442 Black participants) that in
combination present mixed findings. Using multiple emerging measurement/data analysis
frameworks (integrative data analysis (IDA), meta-analysis of individual patient data (MIPD),
causal moderation analysis), the goal of the proposed study is to evaluate the
effectiveness of substance use disorder treatments for Black people who use cocaine.
The project has three specific aims:
Aim 1: Estimate scale scores of cocaine use severity while considering study-level
measurement non-invariance.
Aim 2: Compare the effectiveness of evidence-based treatment models for cocaine use severity.
Aim 3: Explore individual- and study-level moderators, such as concomitant opioid use, age,
sex, employment, pre-treatment psychiatric status, and retention to evaluate subgroup
differences in treatment effectiveness.
使用综合数据分析来检查心理社会治疗对
黑人吸毒者加入NIDA药物滥用治疗临床试验网络
(CTN)
具体目标
最近的报告显示,黑人阿片类药物过量死亡的加速
现在超过了白色人。1这种增长是由于合成的
可卡因供应中的阿片类药物(芬太尼)在阿片类药物过量死亡中约占三分之一。
有限的工作表明,治疗效果可能因种族而异-
种族群体。然而,这些研究中只有一小部分专门研究了可卡因的使用。的
CTN提供了一个独特的,但未充分探索的研究收集,可以提高我们的知识
对吸食可卡因的黑人进行有效的心理治疗拟定的研究将
联合收割机数据来自7项CTN治疗研究(总N = 1442名黑人受试者),
组合呈现混合的结果。使用多种新兴测量/数据分析
框架(综合数据分析(IDA),个体患者数据的荟萃分析(MIPD),
因果适度分析),拟议研究的目标是评估
对使用可卡因的黑人进行物质使用障碍治疗的有效性。
该项目有三个具体目标:
目的1:估计可卡因使用严重程度的量表评分,同时考虑研究水平
测量不变性
目标2:比较可卡因使用严重程度的循证治疗模型的有效性。
目的3:探索个体和研究水平的调节因素,如合并使用阿片类药物,年龄,
性别、就业情况、治疗前精神状态和保留情况,以评价亚组
治疗效果的差异。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('T John WINHUSEN', 18)}}的其他基金
The Ohio Valley Node of the Clinical Trials Network
临床试验网络俄亥俄谷节点
- 批准号:
10652032 - 财政年份:2022
- 资助金额:
$ 3.32万 - 项目类别:
The Ohio Valley Node of the Clinical Trials Network
临床试验网络俄亥俄谷节点
- 批准号:
10621497 - 财政年份:2022
- 资助金额:
$ 3.32万 - 项目类别:
The Ohio Valley Node of the Clinical Trials Network
临床试验网络俄亥俄谷节点
- 批准号:
10441986 - 财政年份:2021
- 资助金额:
$ 3.32万 - 项目类别:
EMPOWER: Evaluating the ability to reduce Morphine equivalent dose for chronic Pain patients receiving Opioid-therapy through a Web-based E-Health self-management program: a Randomized multi-site Clin
EMPOWER:评估通过基于网络的电子健康自我管理计划减少接受阿片类药物治疗的慢性疼痛患者吗啡当量剂量的能力:随机多站点临床
- 批准号:
10174898 - 财政年份:2017
- 资助金额:
$ 3.32万 - 项目类别:
A tailored, peer-delivered intervention to reduce recurring opioid overdoses
量身定制的、同行提供的干预措施,以减少反复出现的阿片类药物过量
- 批准号:
9352799 - 财政年份:2016
- 资助金额:
$ 3.32万 - 项目类别:
A tailored, peer-delivered intervention to reduce recurring opioid overdoses
量身定制的、同行提供的干预措施,以减少反复出现的阿片类药物过量
- 批准号:
9015947 - 财政年份:2016
- 资助金额:
$ 3.32万 - 项目类别:
Clinical Trials Network, Ohio Valley Node U10DA013732
临床试验网络,俄亥俄谷节点 U10DA013732
- 批准号:
8456472 - 财政年份:2000
- 资助金额:
$ 3.32万 - 项目类别:
Clinical Trials Network, Ohio Valley Node U10DA013732
临床试验网络,俄亥俄谷节点 U10DA013732
- 批准号:
8606917 - 财政年份:2000
- 资助金额:
$ 3.32万 - 项目类别:
Clinical Trials Network, Ohio Valley Node U10DA013732
临床试验网络,俄亥俄谷节点 U10DA013732
- 批准号:
8712426 - 财政年份:2000
- 资助金额:
$ 3.32万 - 项目类别:
Clinical Trials Network, Ohio Valley Node U10DA013732
临床试验网络,俄亥俄谷节点 U10DA013732
- 批准号:
8656498 - 财政年份:2000
- 资助金额:
$ 3.32万 - 项目类别:
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