Making space for HIV prevention: substance use among Latinx MSM in LA hotspots

为艾滋病毒预防创造空间：洛杉矶热点地区拉丁裔男男性接触者的药物滥用

• 批准号: 10441997
• 负责人: SUSAN LYNN CASSELS
• 金额: $ 14.87万
• 依托单位: UNIVERSITY OF CALIFORNIA SANTA BARBARA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10441997
• 关键词: AIDS prevention; Address; Administrative Supplement; COVID-19; COVID-19 pandemic; Caring; Clinical; Code; Communities; Community Developments; Community based prevention; Data; Discrimination; Epidemic; Face; Feeling; Funding; Geography; Goals; HIV; HIV Infections; HIV risk; Harm Reduction; Health; Health Personnel; Health Resources; Health care facility; Healthcare; Hospitalization; Incidence; Individual; Intervention; Interview; Knowledge; Latino; Latinx; Link; Loneliness; Mediating; Mental Health; National Institute of Drug Abuse; Outcome; Pharmacists; Population; Psychological Factors; Public Health; Reporting; Research; Respondent; Risk; Risk Factors; Risk Reduction; Sampling; Social Network; Social isolation; Unsafe Sex; Work; acceptability and feasibility; aged; black men who have sex with men; caucasian American; ethnic health disparity; health care settings; health equity; men; men who have sex with men; mortality; parent grant; peer; psychologic; psychological distress; public health intervention; racial and ethnic; racial minority; recruit; service delivery; sex; sexual minority; sexual risk behavior; social; social space; social structure; substance use; substance use prevention; transmission process

Abstract Latino men who have sex with men (MSM) comprise a community that faces elevated risk for disparately negative personal and public health outcomes, including substance use, HIV, and COVID-19 syndemics, and a commuity that remains severely underserved. We propose to examine, in-depth using qualitative interviews, the psychological factors and social spaces that may contribute to substance use and higher rates of HIV among Latinx MSM. This work will supplement our parent grant, which aims to identify and prioritize geographic HIV risk and substance use hotspots among urban, Latinx and Black men who have sex with men. Our work directly engages with issues of health equity among racial and sexual minority men, and is significant because a) targeting risk hotspots is a key priority in the “Ending the HIV Epidemic” initiative, and b) personalized public health, often occurring in different venues other than traditional health facilities within the community, is an effective way to deliver appropriate HIV prevention, care, and treatment. In this supplemental proposal, we address a potential limitation to effective differentiated service delivery, such as peer-driven harm-reduction interventions, in our HIV risk hotspots specifically among Latinx MSM; namely, would these interventions work with socially-isolated individuals who engage in substance use? To achieve our goals, we will sample 40 Latino MSM aged 18-40 who previously participated in our Activity Space research, a study that leverages the NIDA-funded mSTUDY. Our specific aims are: 1) To identify and understand how psychological health factors during COVID-19 (e.g., loneliness, psychological distress) and social network factors (e.g., social isolation, sparse social networks) activate or amplify substance use in HIV risk hotspots; and 2) To assess the acceptability and feasibility of differentiated risk- reduction interventions among Latinx MSM who use substances in the context of the COVID-19 pandemic. The goal-oriented outcome of this work will be additional knowledge on how to best prioritize risk-reduction interventions in Latinx communities outside of healthcare settings. Data will inform the development of community-based prevention and clinical interventions that incorporate key psychological issues, including unique challenges associated with the COVID-19 pandemic, and will therefore have a stronger impact among Latino MSM.

抽象的 男男性行为者 (MSM) 是一个面临较高风险的群体 不同的负面个人和公共健康结果，包括药物使用、艾滋病毒和 COVID-19 流行病，以及服务严重不足的社区。我们建议检查并深入使用 定性访谈、可能导致物质使用的心理因素和社会空间以及 拉丁裔男男性行为者的艾滋病毒感染率较高。这项工作将补充我们的家长补助金，旨在确定和 优先考虑城市、拉丁裔和黑人发生性行为的地理艾滋病毒风险和药物使用热点地区 与男人。我们的工作直接涉及种族和性少数男性的健康公平问题，并且 意义重大，因为 a) 针对风险热点是“结束艾滋病毒流行”计划的一个关键优先事项，以及 b) 个性化公共卫生，通常发生在传统卫生设施以外的不同场所 社区是提供适当的艾滋病毒预防、护理和治疗的有效途径。在这个补充 提案中，我们解决了有效差异化服务交付的潜在限制，例如同行驱动 在我们的艾滋病毒风险热点地区，特别是拉丁裔男男性行为者中，采取减少危害的干预措施；也就是说，这些 干预措施是否适用于从事药物滥用的社会孤立个体？ 为了实现我们的目标，我们将从 40 名 18-40 岁的拉丁裔 MSM 中抽取样本，他们以前参加过我们的项目 活动空间研究，一项利用 NIDA 资助的 mSTUDY 的研究。我们的具体目标是： 1) 识别并了解 COVID-19 期间的心理健康因素（例如孤独、心理 痛苦）和社交网络因素（例如，社交孤立、稀疏的社交网络）激活或放大 艾滋病毒风险热点地区的物质使用； 2) 评估差异化风险的可接受性和可行性- 对在 COVID-19 大流行背景下使用药物的拉丁裔 MSM 进行减少干预措施。这 这项工作以目标为导向的成果将是关于如何最好地优先考虑降低风险的更多知识 对医疗机构之外的拉丁裔社区进行干预。数据将为发展提供信息 以社区为基础的预防和临床干预，其中包括关键的心理问题，包括 与 COVID-19 大流行相关的独特挑战，因此将对 拉丁裔男男性接触者。

项目成果

Novel Location-Based Survey Using Cognitive Interviews to Assess Geographic Networks and Hotspots of Sex and Drug Use: Implementation and Validation Study.

使用认知访谈来评估性别和药物使用的地理网络和热点的新型基于位置的调查：实施和验证研究。

• DOI: 10.2196/45188
• 发表时间: 2023-06-22
• 期刊: JMIR FORMATIVE RESEARCH
• 影响因子: 2.2
• 作者: Reid, Sean C.;Wang, Vania;Assaf, Ryan;Kaloper, Sofia;Murray, Alan;Shoptaw, Steven;Gorbach, Pamina;Cassels, Susan
• 通讯作者: Cassels, Susan

A call for epidemic modeling to examine historical and structural drivers of racial disparities in infectious disease.

• DOI: 10.1016/j.socscimed.2021.113833
• 发表时间: 2021-05
• 期刊: Social science & medicine (1982)
• 作者: Cassels S;Van Den Abbeele S
• 通讯作者: Van Den Abbeele S

Geographic mobility and its impact on sexual health and ongoing HIV transmission among migrant latinx men who have sex with men.

地理流动性及其对性健康的影响以及与男性发生性行为的拉丁移民男性中持续的艾滋病毒传播。

• DOI: 10.1016/j.socscimed.2022.115635
• 发表时间: 2023
• 期刊: Social science & medicine (1982)
• 作者: Cassels,Susan;Cerezo,Alison;Reid,SeanC;Rivera,DavidB;Loustalot,Colin;Meltzer,Dan
• 通讯作者: Meltzer,Dan