Migration to Urban Slums, Sexual Networks, and HIV in Ghana

这项研究的长期目标是使用基于动态网络的人类迁移和艾滋病毒传播动态的数学模型来设计和评估艾滋病毒预防干预措施，如并发消息。本研究项目有三个具体目标。第一个目标是审查加纳关于移徙和艾滋病毒的现有数据。本文的文献综述和实证研究将1）强调 加纳的移民模式和艾滋病毒差异2）强调了我们对移民和艾滋病毒传播之间复杂联系的认识存在差距，3）揭示了标准横截面数据收集的局限性。这一分析的结果将为第二个目标中的问卷设计提供信息。 因此，本研究的第二个目的是设计和实施一个小规模的试点调查的性网络，移民史，艾滋病毒的性危险行为。PI还将确定收集HIV生物标志物的可行性，用于未来的跨学科工作。第三个目标是根据网络样本建立一个数学模型，以量化移徙对艾滋病毒传播的影响。这项试点建模工作将成为ROO资助周期结束时R01申请的基础。

The long-term objective of this research is to use dynamic network-based mathematical models of human migration and HIV transmission dynamics for designing and evaluating HIV prevention interventions, such as the message of concurrency. There are three specific aims of this research project. The first aim is to review existing data on migration and HIV in Ghana. This literature review and empirical research will 1) highlight migration patterns and HIV disparities in Ghana 2) emphasize gaps in our knowledge ofthe complex association between migration and HIV transmission, and 3) reveal the limitations of standard crosssectional data collection. The results of this analysis will inform the questionnaire design in the second aim. Thus the second aim of this research is to design and implement a small-scale pilot survey of sexual networks, migration history, and HIV sexual risk behaviors. The PI will also determine the feasibility of collecting HIV biomarkers for HIV for future cross-discipline work. The third aim is to develop a mathematical model based on the network sample in order to quantify the impact of migration on the spread of HIV. This pilot modeling work will be the basis of an R01 application toward the end of the ROO grant cycle.