Migration to Urban Slums, Sexual Networks, and HIV in Ghana

这项研究的长期目标是使用基于网络的人类迁徙和艾滋病毒传播动力学的动态数学模型来设计和评估艾滋病毒预防干预措施，如并发消息。本研究项目有三个具体目的。第一个目标是审查加纳现有的移民和艾滋病毒数据。这篇文献综述和实证研究将突出1) 加纳的移徙模式和艾滋病毒差距2)强调了我们对移徙和艾滋病毒传播之间复杂联系的认识上的差距，3)揭示了标准横断面数据收集的局限性。这一分析的结果将为第二个目标中的问卷设计提供参考。 因此，这项研究的第二个目标是设计和实施一项关于性网络、迁徙历史和HIV性危险行为的小规模试点调查。该小组还将确定为今后的跨学科工作收集艾滋病毒生物标记物的可行性。第三个目标是根据网络样本建立一个数学模型，以量化移徙对艾滋病毒传播的影响。这项试点建模工作将成为R01应用程序的基础，直到RoO赠款周期结束。

The long-term objective of this research is to use dynamic network-based mathematical models of human migration and HIV transmission dynamics for designing and evaluating HIV prevention interventions, such as the message of concurrency. There are three specific aims of this research project. The first aim is to review existing data on migration and HIV in Ghana. This literature review and empirical research will 1) highlight migration patterns and HIV disparities in Ghana 2) emphasize gaps in our knowledge ofthe complex association between migration and HIV transmission, and 3) reveal the limitations of standard crosssectional data collection. The results of this analysis will inform the questionnaire design in the second aim. Thus the second aim of this research is to design and implement a small-scale pilot survey of sexual networks, migration history, and HIV sexual risk behaviors. The PI will also determine the feasibility of collecting HIV biomarkers for HIV for future cross-discipline work. The third aim is to develop a mathematical model based on the network sample in order to quantify the impact of migration on the spread of HIV. This pilot modeling work will be the basis of an R01 application toward the end of the ROO grant cycle.