Influence of patient-centered HIV care on retention and viral suppression disparities

摘要 人类免疫缺陷病毒携带者患新冠肺炎并发症的风险增加 潜在的免疫抑制和并发症，因此可以显著受益于新冠肺炎 接种疫苗。艾滋病毒携带者(PWH)也更有可能属于以下种族/少数民族 不成比例地承受着新冠肺炎大流行的负担，目前在 接种疫苗的人。这项研究的目的是找出增加新冠肺炎的干预点 非洲裔美国人、西班牙裔美国人和海地威尔斯亲王医院的疫苗接种情况。为了达到这一目标，我们将 进行一项混合方法研究，样本包括129名拉美裔美国人、116名非裔美国人和53名海地人 曾在2020年10月至2021年1月就COVID的影响接受过采访的艾滋病毒携带者- 19大流行对他们的健康和福祉以及他们的艾滋病毒护理(第一波)。目前的增刊(第二波)将 通过确定新冠肺炎疫苗的接种率和与疫苗相关的因素来扩展先前的研究 领悟。调查问题将收集与疫苗接种相关的因素的量化数据，使用 健康信念模型(例如，感知的新冠肺炎易感性、感知的新冠肺炎严重程度、感知的 新冠肺炎疫苗接种的障碍和好处以及行动的线索)和社会生态模型(即， 与新冠肺炎相关的潜在个人内部、人际关系和社区/机构层面的因素 疫苗接种)。调查数据还将用于确定新冠肺炎疫苗接种的程度 改善心理社会(例如，新冠肺炎相关的担忧)和社会经济(例如，收入减少)压力源。 此外，我们将进行探索性分析，以评估疫苗接种和 保留艾滋病毒护理和病毒抑制。随后，我们将要求接种疫苗和 未接种疫苗调查受访者参加半结构化深度访谈，澄清量化 调查结果并确定干预点。这项研究的发现将指导疫苗接种宣传信息 对于感染艾滋病毒的种族/族裔少数群体，指导疫苗接种提供方法(例如，在艾滋病毒护理环境中接种疫苗)， 并阐明新冠肺炎疫苗接种在改善慢性病患者健康福祉方面的潜在作用 爱滋病毒。

Abstract People with human immunodeficiency virus (HIV) are at increased risk of COVID-19 complications due to underlying immunosuppression and comorbidities and thus can significantly benefit from COVID-19 vaccination. People with HIV (PWH) are also more likely to belong to racial/ethnic minorities that have been disproportionately burdened by the COVID-19 pandemic and are currently underrepresented among vaccinated individuals. The objective of this study is to identify points of intervention to increase COVID-19 vaccine uptake among African American, Hispanic, and Haitian PWH. To achieve this objective, we will conduct a mixed methods study involving a sample of 129 Hispanics, 116 African Americans and 53 Haitians with HIV who were previously interviewed from October 2020 to January 2021 about the effect of the COVID- 19 pandemic on their health and wellbeing and their HIV care (Wave 1). The current supplement (Wave 2) will extend the previous study by determining COVID-19 vaccine uptake and factors associated with vaccine uptake. The survey questions will collect quantitative data about factors associated with vaccination using both the Health Belief Model (e.g., perceived susceptibility to COVID-19, perceived severity of COVID-19, perceived barriers and benefits of COVID-19 vaccination, and cues to action) and the Social Ecological Model (i.e., potential intrapersonal, interpersonal, and community/institutional-level factors associated with COVID-19 vaccine uptake). Data from the survey will also be used to identify the extent to which COVID-19 vaccination improves psychosocial (e.g., COVID-19 related worry) and socioeconomic (e.g., reduced income) stressors. Furthermore, we will conduct exploratory analyses to assess the association between vaccination and retention in HIV care and viral suppression. Subsequently, we will ask a sample of vaccinated and unvaccinated survey respondents to participate in semi-structured in-depth interviews to clarify quantitative findings and identify points of intervention. Findings from this study will guide vaccination promotion messages for racial/ethnic minorities with HIV, guide vaccination delivery methods (e.g., vaccination in HIV care settings), and elucidate the potential role of COVID-19 vaccination in improving the health and wellbeing of people with HIV.