Training the Next Generation of Chemical Biologists

项目摘要 这个令人兴奋的博士前培训计划在化学生物学接口涉及30名培训教师 来自明尼苏达大学的三个系，包括化学，药物化学， 生物化学，分子生物学和生物物理学（BMBB）。该计划的使命是提供一个多样化的 学生干部具有必要的技能，跨越传统的界限，批判性地思考和理解， 在化学和生物学的交界处进行严格的科学研究。这个使命一定会完成 实现以下七个具体目标。随着时间的推移，预计受训人员将在以下方面取得进展： 他们在职业意识，化学生物学知识， 专业的科学家开发，严谨性和可重复性。成功实现这些目标将是 通过使用定量指标进行评估。这一使命将通过实现以下目标来完成 目标： (i)为学生提供化学和生物学界面的跨学科培训体验。这将 通过涉及来自三个不同部门的课程的组合，并通过一个 交叉培训经验，包括共同顾问和至少三个月的研究经验， 共同顾问实验室 (ii)通过结合在线介绍、课堂教学、 指导和互动讲习班。 (iii)通过集中讨论会，让学生接触到化学和生物学界面的前沿科学 在这种类型的界面科学（化学生物学座谈会，CBC），并允许他们组织他们的 自己的研讨会集中在化学生物学接口。 (iv)通过为学员提供多种机会来展示他们的 以不同形式进行研究，包括在国家或国际会议上发表演讲。 (v)教育学生关于职业机会的范围可供科学家在这方面的培训。 (vi)通过让当地高中的学生、教师和工业科学家参与培训计划，激发他们的兴趣。 学校、四年制学院和公司的培训活动。 (vii)增加科学家的多样性，在我们的化学和生物学界面进行研究， 通过不同的推广活动相结合的方案。 与该计划有关的研究将涵盖广泛的主题， 发展基础化学技术，发现新的生物学，研究和治疗 包括癌症、衰老和传染病在内的疾病。培训教师是一个高度合作的 集团与导师之间的联合出版物的丰富历史，并致力于投入时间， 努力有效地指导学生。

Project Summary This exciting pre-doctoral training program at the Chemistry-Biology Interface involves 30 training faculty from three departments at the University of Minnesota including Chemistry, Medicinal Chemistry, and Biochemistry, Molecular Biology and Biophysics (BMBB). The mission of the program is to provide a diverse cadre of students with the skills necessary to cross traditional boundaries, think critically and understand and conduct rigorous scientific research at the interface of chemistry and biology. This mission will be accomplished by achieving the seven specific objectives listed below. Over time, it is expected that trainees will progress in their development as professional scientists in the areas of career awareness, knowledge of chemical biology, professional scientist development, and rigor and reproducibility. Success in achieving those goals will be evaluated through the use of quantitative metrics. This mission will be accomplished by achieving the following objectives: (i) Provide students with an interdisciplinary training experience at the interface of chemistry and biology. This will be accomplished by a combination of coursework involving classes from three different departments and by a cross-training experience involving a coadvisor and a research experience of at least three months in the coadvisors laboratory. (ii) Promote rigor and reproducibility in research through a combination of an online introduction, classroom instruction and interactive workshops. (iii) Expose students to cutting-edge science at the interface of chemistry and biology through seminars focused on this type of interfacial science (Chemical Biology Colloquium, CBC) and by allowing them to organize their own symposium focused on the chemical biology interface. (iv) Enhance the communication skills of trainees by providing them with multiple opportunities to present their research in different formats including a presentation at a national or international conference. (v) Educate students about the range of career opportunities available for scientists with training in this area. (vi) Stimulate interest in the training program by involving students, faculty and industrial scientists from local high schools, four-year colleges and companies in training activities. (vii) Increase the diversity of scientists carrying out research at the chemistry and biology interface in our program through a combination of different outreach activities. Research carried out in connection with the program will span a wide range of topics ranging from the development of fundamental chemical technologies to discover new biology, to the study and treatment of diseases including cancer, aging and infectious disease. The training faculty members are a highly collaborative group with a rich history of joint publications among the mentors and are committed to devoting the time and effort it takes to effectively mentor students.