Training the Next Generation of Chemical Biologists

项目摘要 这一令人兴奋的博士前培训计划在化学-生物学接口，涉及30名培训教师 来自明尼苏达大学的三个系，包括化学，药物化学和 生物化学、分子生物学和生物物理学(BMBB)。该计划的使命是提供多样化的 具备跨越传统界限、批判性思维和理解能力的学生干部队伍 在化学和生物的交界处进行严谨的科学研究。这项任务一定会完成的 通过实现下面列出的七个具体目标。随着时间的推移，预计受训人员将在 他们在职业意识、化学生物学知识、 专业的科学家发展，严谨和可重复性。实现这些目标的成功将是 通过使用量化指标进行评估。这项任务将通过实现以下目标来完成 目标： (I)为学生提供化学和生物相结合的跨学科培训体验。这将是 通过三个不同部门的班级参与的课程作业和一个 有联合顾问参与的交叉培训经验，以及至少三个月的研究经验 协理实验室。 (2)通过在线介绍、课堂教学相结合的方式促进研究的严谨性和可重复性 指导和互动研讨会。 (3)通过专题讨论会，让学生接触化学和生物的前沿科学 关于这种类型的界面科学(化学生物学研讨会，CBC)，并允许他们组织他们的 自己的研讨会聚焦于化学生物学界面。 (4)加强学员的沟通技巧，为学员提供多方面的机会介绍他们的意见 以不同的形式进行研究，包括在国家或国际会议上发表演讲。 (V)教育学生了解接受过该领域培训的科学家可获得的各种职业机会。 (Vi)通过吸收本地高中的学生、教员和工业科学家参与，激发对培训计划的兴趣 学校、四年制大专院校和企业开展培训活动。 (Vii)增加在我们的化学和生物界面进行研究的科学家的多样性 通过不同的外展活动相结合的方案。 与该计划有关的研究将涵盖广泛的主题，从 发展基础化学技术，以发现新的生物学，研究和治疗 包括癌症、老龄化和传染病在内的疾病。培训教员是高度合作的 集团拥有丰富的联合出版历史的导师，并致力于致力于时间和 要有效地指导学生，就需要付出努力。

Project Summary This exciting pre-doctoral training program at the Chemistry-Biology Interface involves 30 training faculty from three departments at the University of Minnesota including Chemistry, Medicinal Chemistry, and Biochemistry, Molecular Biology and Biophysics (BMBB). The mission of the program is to provide a diverse cadre of students with the skills necessary to cross traditional boundaries, think critically and understand and conduct rigorous scientific research at the interface of chemistry and biology. This mission will be accomplished by achieving the seven specific objectives listed below. Over time, it is expected that trainees will progress in their development as professional scientists in the areas of career awareness, knowledge of chemical biology, professional scientist development, and rigor and reproducibility. Success in achieving those goals will be evaluated through the use of quantitative metrics. This mission will be accomplished by achieving the following objectives: (i) Provide students with an interdisciplinary training experience at the interface of chemistry and biology. This will be accomplished by a combination of coursework involving classes from three different departments and by a cross-training experience involving a coadvisor and a research experience of at least three months in the coadvisors laboratory. (ii) Promote rigor and reproducibility in research through a combination of an online introduction, classroom instruction and interactive workshops. (iii) Expose students to cutting-edge science at the interface of chemistry and biology through seminars focused on this type of interfacial science (Chemical Biology Colloquium, CBC) and by allowing them to organize their own symposium focused on the chemical biology interface. (iv) Enhance the communication skills of trainees by providing them with multiple opportunities to present their research in different formats including a presentation at a national or international conference. (v) Educate students about the range of career opportunities available for scientists with training in this area. (vi) Stimulate interest in the training program by involving students, faculty and industrial scientists from local high schools, four-year colleges and companies in training activities. (vii) Increase the diversity of scientists carrying out research at the chemistry and biology interface in our program through a combination of different outreach activities. Research carried out in connection with the program will span a wide range of topics ranging from the development of fundamental chemical technologies to discover new biology, to the study and treatment of diseases including cancer, aging and infectious disease. The training faculty members are a highly collaborative group with a rich history of joint publications among the mentors and are committed to devoting the time and effort it takes to effectively mentor students.