Training the Next Generation of Chemical Biologists

项目概要 这个激动人心的化学-生物界面博士前培训项目涉及 30 名培训教师 来自明尼苏达大学三个系，包括化学、药物化学和 生物化学、分子生物学和生物物理学（BMBB）。该计划的使命是提供多样化的 学生骨干具有跨越传统界限、批判性思考、理解和理解所必需的技能 在化学和生物学的交叉领域进行严格的科学研究。这个使命一定会完成 通过实现下列七个具体目标。随着时间的推移，预计学员将在以下方面取得进步： 他们作为专业科学家在职业意识、化学生物学知识、 专业科学家的发展、严谨性和可重复性。成功实现这些目标将 通过使用定量指标进行评估。这一使命将通过实现以下目标来完成 目标： (i) 为学生提供化学和生物学交叉学科的跨学科培训经验。这将 通过涉及三个不同部门的课程的组合以及由 涉及联合导师的交叉培训经验和至少三个月的研究经验 联合顾问实验室。 (ii) 通过在线介绍、课堂教学相结合，促进研究的严谨性和可重复性 指导和互动研讨会。 (iii) 通过重点研讨会让学生接触化学和生物学交叉领域的尖端科学 关于这种类型的界面科学（化学生物学研讨会，CBC）并允许他们组织他们的 自己的研讨会重点关注化学生物学界面。 (iv) 为受训者提供多种展示自己的机会，从而提高他们的沟通技巧 以不同形式进行研究，包括在国内或国际会议上的演讲。 (v) 让学生了解接受过该领域培训的科学家可以获得的职业机会范围。 (vi) 通过让当地高等院校的学生、教师和工业科学家参与进来，激发对培训计划的兴趣 学校、四年制学院和公司的培训活动。 (vii) 增加在我们的化学和生物学界面进行研究的科学家的多样性 通过结合不同的外展活动来制定计划。 与该计划相关的研究将涵盖广泛的主题，从 发展基础化学技术以发现新的生物学、研究和治疗 疾病包括癌症、衰老和传染病。培训师资队伍高度协作 该小组在导师之间拥有丰富的联合出版物历史，并致力于投入时间和精力 有效指导学生所需的努力。

Project Summary This exciting pre-doctoral training program at the Chemistry-Biology Interface involves 30 training faculty from three departments at the University of Minnesota including Chemistry, Medicinal Chemistry, and Biochemistry, Molecular Biology and Biophysics (BMBB). The mission of the program is to provide a diverse cadre of students with the skills necessary to cross traditional boundaries, think critically and understand and conduct rigorous scientific research at the interface of chemistry and biology. This mission will be accomplished by achieving the seven specific objectives listed below. Over time, it is expected that trainees will progress in their development as professional scientists in the areas of career awareness, knowledge of chemical biology, professional scientist development, and rigor and reproducibility. Success in achieving those goals will be evaluated through the use of quantitative metrics. This mission will be accomplished by achieving the following objectives: (i) Provide students with an interdisciplinary training experience at the interface of chemistry and biology. This will be accomplished by a combination of coursework involving classes from three different departments and by a cross-training experience involving a coadvisor and a research experience of at least three months in the coadvisors laboratory. (ii) Promote rigor and reproducibility in research through a combination of an online introduction, classroom instruction and interactive workshops. (iii) Expose students to cutting-edge science at the interface of chemistry and biology through seminars focused on this type of interfacial science (Chemical Biology Colloquium, CBC) and by allowing them to organize their own symposium focused on the chemical biology interface. (iv) Enhance the communication skills of trainees by providing them with multiple opportunities to present their research in different formats including a presentation at a national or international conference. (v) Educate students about the range of career opportunities available for scientists with training in this area. (vi) Stimulate interest in the training program by involving students, faculty and industrial scientists from local high schools, four-year colleges and companies in training activities. (vii) Increase the diversity of scientists carrying out research at the chemistry and biology interface in our program through a combination of different outreach activities. Research carried out in connection with the program will span a wide range of topics ranging from the development of fundamental chemical technologies to discover new biology, to the study and treatment of diseases including cancer, aging and infectious disease. The training faculty members are a highly collaborative group with a rich history of joint publications among the mentors and are committed to devoting the time and effort it takes to effectively mentor students.