Training the Next Generation of Chemical Biologists

培训下一代化学生物学家

• 批准号: 10441331
• 负责人: MARK D DISTEFANO
• 金额: $ 37.18万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10441331
• 关键词: Chemicals; Training; next generation

Project Summary This exciting pre-doctoral training program at the Chemistry-Biology Interface involves 30 training faculty from three departments at the University of Minnesota including Chemistry, Medicinal Chemistry, and Biochemistry, Molecular Biology and Biophysics (BMBB). The mission of the program is to provide a diverse cadre of students with the skills necessary to cross traditional boundaries, think critically and understand and conduct rigorous scientific research at the interface of chemistry and biology. This mission will be accomplished by achieving the seven specific objectives listed below. Over time, it is expected that trainees will progress in their development as professional scientists in the areas of career awareness, knowledge of chemical biology, professional scientist development, and rigor and reproducibility. Success in achieving those goals will be evaluated through the use of quantitative metrics. This mission will be accomplished by achieving the following objectives: (i) Provide students with an interdisciplinary training experience at the interface of chemistry and biology. This will be accomplished by a combination of coursework involving classes from three different departments and by a cross-training experience involving a coadvisor and a research experience of at least three months in the coadvisors laboratory. (ii) Promote rigor and reproducibility in research through a combination of an online introduction, classroom instruction and interactive workshops. (iii) Expose students to cutting-edge science at the interface of chemistry and biology through seminars focused on this type of interfacial science (Chemical Biology Colloquium, CBC) and by allowing them to organize their own symposium focused on the chemical biology interface. (iv) Enhance the communication skills of trainees by providing them with multiple opportunities to present their research in different formats including a presentation at a national or international conference. (v) Educate students about the range of career opportunities available for scientists with training in this area. (vi) Stimulate interest in the training program by involving students, faculty and industrial scientists from local high schools, four-year colleges and companies in training activities. (vii) Increase the diversity of scientists carrying out research at the chemistry and biology interface in our program through a combination of different outreach activities. Research carried out in connection with the program will span a wide range of topics ranging from the development of fundamental chemical technologies to discover new biology, to the study and treatment of diseases including cancer, aging and infectious disease. The training faculty members are a highly collaborative group with a rich history of joint publications among the mentors and are committed to devoting the time and effort it takes to effectively mentor students.

项目摘要 化学生物学界面上令人兴奋的博士前培训计划涉及30个培训教师 来自明尼苏达大学的三个系，包括化学，药物化学和 生物化学，分子生物学和生物物理学（BMBB）。该计划的任务是提供多样化 学生的干部具有跨越传统界限，批判性思考和理解和 在化学与生物学界面进行严格的科学研究。这个任务将完成 通过实现以下列出的七个特定目标。随着时间的流逝，预计学员将进步 他们在职业意识，化学生物学知识方面作为专业科学家的发展， 专业科学家的发展，严格和可重复性。实现这些目标的成功将是 通过使用定量指标进行评估。该任务将通过实现以下操作来完成 目标： （i）为学生提供化学和生物学界面的跨学科培训经验。这会 可以通过涉及三个不同部门的课程的课程组合来完成 涉及共顾问和至少三个月的研究经验的跨训练经验 协同实验室。 （ii）通过在线介绍，课堂的结合结合在研究中促进严格和可重复性 教学和互动研讨会。 （iii）通过以研讨会为重点 关于这种类型的界面科学（化学生物学座谈会，CBC），并允许它们组织 自己的研讨会着重于化学生物学界面。 （iv）通过为受训者提供多种机会来提高学员的沟通技巧 以不同格式进行研究，包括在国家或国际会议上演讲。 （v）向学生教育在该领域接受培训的科学家提供的一系列职业机会。 （vi）通过参与来自当地高级的学生，教职员工和工业科学家来激发人们对培训计划的兴趣 学校，四年制大学和公司从事培训活动。 （vii）增加在我们的化学和生物学界面进行研究的科学家的多样性 通过不同的外展活动组合进行编程。 与该计划有关的研究将跨越各种主题 开发基本化学技术，以发现新的生物学，研究和治疗 包括癌症，衰老和传染病在内的疾病。培训教师是高度合作的 团体拥有丰富的导师共同出版物的历史，并致力于花时间和时间 有效指导学生所需的努力。