An Adaptive Intervention Trial of Home Testing with Behavioral Nudges for Improving COVID-19 Testing and Prevention among People Affected by Diabetes

通过行为助推进行家庭检测的适应性干预试验，以改善糖尿病患者的 COVID-19 检测和预防

• 批准号: 10447445
• 负责人: Kabayam M Venkat Narayan
• 金额: $ 115.67万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-07 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10447445
• 关键词: Address; Adherence; Adoption; Adult; Affect; African American; Age; Appointment; Attitude; Behavior; Behavioral; Black American; Black race; COVID-19; COVID-19 mortality; COVID-19 pandemic; COVID-19 prevention; COVID-19 risk; COVID-19 test; COVID-19 testing; COVID-19 vaccination; COVID-19 vaccine; Car Phone; Caring; Climate; Clinic; Collaborations; Collection; Communities; Community Health; County; Data; Data Collection; Death Rate; Diabetes Mellitus; Diagnostic Reagent Kits; Disadvantaged; Epidemiology; Ethnic Origin; Face; Family member; Funding; Health; Health behavior; Home; Hospitals; Household and Family; Individual; Institutes; Institution; Intervention Studies; Intervention Trial; Interview; Knowledge; Latinx; Long COVID; Masks; Methods; Minority; Minority Groups; Modeling; Monitor; Morehouse School of Medicine; Obesity; Participant; Peach; Perception; Persons; Phase; Play; Population; Positive Reinforcements; Prediabetes syndrome; Preventive; RADx Underserved Populations; Race; Randomized; Recording of previous events; Reporting; Research; Research Personnel; Resistance; Risk; Role; SARS-CoV-2 infection; Schedule; Site; Social Distance; Suggestion; Surveys; System; Technology; Test Result; Testing; Text; Text Messaging; Time; Translational Research; Universities; Vaccination; Vaccines; Vulnerable Populations; adaptive intervention; base; behavior change; behavioral study; community partnership; design; diabetes risk; disorder prevention; follow-up; high risk; high risk population; home test; improved; informant; interest; member; news; pandemic disease; programs; recruit; sex; social; social media; social stigma; socioeconomics; study population; testing uptake; uptake; vaccine acceptance; vaccine distribution; vaccine hesitancy; vulnerable community

ABSTRACT This multi-institution team (Emory University, Morehouse School of Medicine, Georgia Institute of Technology), anchored by the Georgia Center for Diabetes Translation Research (P30DK111024) partnership, proposes to leverage and expand on the on-going, RADx-UP funded Project PEACH (P30DK111024), to design and evaluate a home-based COVID-19 testing program with behavioral nudges delivered via mobile phone texts to increase uptake of COVID-19 prevention activities (testing, vaccination, preventive behaviors) in “An Adaptive Intervention Trial of Home Testing with Behavioral Nudges for Improving COVID-19 Testing and Prevention among People Affected by Diabetes.” COVID-19 testing remains a cornerstone in understanding and managing the COVID-19 pandemic. The state of Georgia faces several challenges to COVID-19 management including low vaccine rates, over-extended community health partners struggling to manage both COVID-19 testing and vaccination, decreasing COVID-19 testing numbers, and large populations at elevated risk, including those with or at risk for diabetes, individuals at lower socioeconomic levels, and African American/Black and LatinX communities. In Project PEACH2, we propose to leverage the community partnerships developed and expanded at part of Project PEACH to gather additional information on COVID-19 testing, with a particular focus on at-home testing solutions (Aim 1), using both quantitative (an expansion of the follow-up surveys already being conducted as part of Project PEACH) and qualitative (in-depth interviews with 100 community members, key stakeholders, and community partners) methods. This data, along with the findings of Project PEACH and Georgia CEAL (1OT2HL156812-01/16-312-0217571-66105L), will be used to develop text message, behavioral nudges to promote continued COVID-19 testing, reporting and preventive behaviors including vaccination targeted to participants’ race/ethnicity, sex, age, vaccination status, and testing history. We will then evaluate (Aim 2a) the uptake, usage, and views of a home testing platform (provision a single home COVID-19 test kit for each household family member, collection of test results via an online reporting system, and targeted behavioral nudges delivered via text messages) in a randomized community- based, adaptive intervention trial (n=600) targeting individuals affected by diabetes through collaborations with community partner sites (faith- and community-based organization, the Grady Diabetes Clinic, COVID-19 community testing and vaccine distribution sites). We will also assess (Aim 2b) how the home testing platform affects vaccine uptake and hesitancy among study participants and family members. This study will build on the successful community-academic partnerships created through Project PEACH to further promote COVID- 19 testing among the most vulnerable communities in Georgia. Lessons learned can be disseminated to other at-risk communities and can be adapted to promote home-based testing for other conditions.

摘要 这个多机构团队（埃默里大学、莫尔豪斯医学院、格鲁吉亚理工学院）， 由格鲁吉亚糖尿病翻译研究中心（P30 DK 111024）合作，建议 利用和扩展正在进行的，RADx-UP资助的项目PEACH（P30 DK 111024），设计和 通过移动的电话提供行为提示，评估基于家庭的COVID-19检测计划 文本，以增加吸收COVID-19预防活动（检测，疫苗接种，预防行为）在“一个 家庭测试与行为推动的适应性干预试验，以改善COVID-19检测 糖尿病患者的预防”。COVID-19检测仍然是 了解和管理COVID-19疫情。格鲁吉亚州面临着几个挑战， COVID-19管理，包括低疫苗接种率，过度扩展的社区卫生合作伙伴， 管理COVID-19检测和疫苗接种，减少COVID-19检测数量和大量人口 高风险人群，包括患有糖尿病或有糖尿病风险的人群，社会经济水平较低的人群，以及 非裔美国人/黑人和拉丁裔社区。在PEACH 2项目中，我们建议利用社区 在PEACH项目的一部分发展和扩大伙伴关系，以收集有关COVID-19的更多信息 测试，特别关注家庭测试解决方案（目标1），使用定量（扩展 作为PEACH项目的一部分已经进行的后续调查）和定性调查（深入访谈 与100名社区成员、主要利益相关者和社区合作伙伴）的方法。这些数据沿着 项目PEACH和格鲁吉亚CEAL（1 OT 2 HL 156812 -01/16-312-0217571- 66105 L）的调查结果将用于 开发短信、行为提示，以促进持续的COVID-19检测、报告和预防 行为，包括针对参与者种族/民族、性别、年龄、疫苗接种状态和检测的疫苗接种 历史然后，我们将评估（目标2a）家庭测试平台的吸收、使用和观点（提供a 为每个家庭成员提供一个家庭COVID-19检测试剂盒，通过在线收集检测结果 报告系统，以及通过短信传递的有针对性的行为轻推）在一个随机的社区- 基于适应性干预试验（n=600），通过与 社区合作伙伴网站（信仰和社区组织，格雷迪糖尿病诊所，COVID-19 社区测试和疫苗分发点）。我们还将评估（目标2b）家庭测试平台 影响研究参与者和家庭成员的疫苗接种和犹豫。这项研究将建立在 通过PEACH项目建立的成功的社区-学术合作伙伴关系，以进一步宣传COVID-19， 19在格鲁吉亚最脆弱的社区进行测试。吸取的经验教训可以传播给其他 该方法适用于高风险社区，并可用于促进其他条件的家庭检测。