An Adaptive Intervention Trial of Home Testing with Behavioral Nudges for Improving COVID-19 Testing and Prevention among People Affected by Diabetes

通过行为助推进行家庭检测的适应性干预试验，以改善糖尿病患者的 COVID-19 检测和预防

• 批准号: 10447445
• 负责人: Kabayam M Venkat Narayan
• 金额: $ 115.67万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-07 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10447445
• 关键词: Address; Adherence; Adoption; Adult; Affect; African American; Age; Appointment; Attitude; Behavior; Behavioral; Black American; Black race; COVID-19; COVID-19 mortality; COVID-19 pandemic; COVID-19 prevention; COVID-19 risk; COVID-19 test; COVID-19 testing; COVID-19 vaccination; COVID-19 vaccine; Car Phone; Caring; Climate; Clinic; Collaborations; Collection; Communities; Community Health; County; Data; Data Collection; Death Rate; Diabetes Mellitus; Diagnostic Reagent Kits; Disadvantaged; Epidemiology; Ethnic Origin; Face; Family member; Funding; Health; Health behavior; Home; Hospitals; Household and Family; Individual; Institutes; Institution; Intervention Studies; Intervention Trial; Interview; Knowledge; Latinx; Long COVID; Masks; Methods; Minority; Minority Groups; Modeling; Monitor; Morehouse School of Medicine; Obesity; Participant; Peach; Perception; Persons; Phase; Play; Population; Positive Reinforcements; Prediabetes syndrome; Preventive; RADx Underserved Populations; Race; Randomized; Recording of previous events; Reporting; Research; Research Personnel; Resistance; Risk; Role; SARS-CoV-2 infection; Schedule; Site; Social Distance; Suggestion; Surveys; System; Technology; Test Result; Testing; Text; Text Messaging; Time; Translational Research; Universities; Vaccination; Vaccines; Vulnerable Populations; adaptive intervention; base; behavior change; behavioral study; community partnership; design; diabetes risk; disorder prevention; follow-up; high risk; high risk population; home test; improved; informant; interest; member; news; pandemic disease; programs; recruit; sex; social; social media; social stigma; socioeconomics; study population; testing uptake; uptake; vaccine acceptance; vaccine distribution; vaccine hesitancy; vulnerable community

ABSTRACT This multi-institution team (Emory University, Morehouse School of Medicine, Georgia Institute of Technology), anchored by the Georgia Center for Diabetes Translation Research (P30DK111024) partnership, proposes to leverage and expand on the on-going, RADx-UP funded Project PEACH (P30DK111024), to design and evaluate a home-based COVID-19 testing program with behavioral nudges delivered via mobile phone texts to increase uptake of COVID-19 prevention activities (testing, vaccination, preventive behaviors) in “An Adaptive Intervention Trial of Home Testing with Behavioral Nudges for Improving COVID-19 Testing and Prevention among People Affected by Diabetes.” COVID-19 testing remains a cornerstone in understanding and managing the COVID-19 pandemic. The state of Georgia faces several challenges to COVID-19 management including low vaccine rates, over-extended community health partners struggling to manage both COVID-19 testing and vaccination, decreasing COVID-19 testing numbers, and large populations at elevated risk, including those with or at risk for diabetes, individuals at lower socioeconomic levels, and African American/Black and LatinX communities. In Project PEACH2, we propose to leverage the community partnerships developed and expanded at part of Project PEACH to gather additional information on COVID-19 testing, with a particular focus on at-home testing solutions (Aim 1), using both quantitative (an expansion of the follow-up surveys already being conducted as part of Project PEACH) and qualitative (in-depth interviews with 100 community members, key stakeholders, and community partners) methods. This data, along with the findings of Project PEACH and Georgia CEAL (1OT2HL156812-01/16-312-0217571-66105L), will be used to develop text message, behavioral nudges to promote continued COVID-19 testing, reporting and preventive behaviors including vaccination targeted to participants’ race/ethnicity, sex, age, vaccination status, and testing history. We will then evaluate (Aim 2a) the uptake, usage, and views of a home testing platform (provision a single home COVID-19 test kit for each household family member, collection of test results via an online reporting system, and targeted behavioral nudges delivered via text messages) in a randomized community- based, adaptive intervention trial (n=600) targeting individuals affected by diabetes through collaborations with community partner sites (faith- and community-based organization, the Grady Diabetes Clinic, COVID-19 community testing and vaccine distribution sites). We will also assess (Aim 2b) how the home testing platform affects vaccine uptake and hesitancy among study participants and family members. This study will build on the successful community-academic partnerships created through Project PEACH to further promote COVID- 19 testing among the most vulnerable communities in Georgia. Lessons learned can be disseminated to other at-risk communities and can be adapted to promote home-based testing for other conditions.

抽象的 这个多机构团队（埃默里大学、莫尔豪斯医学院、佐治亚理工学院）， 由乔治亚州糖尿病翻译研究中心 (P30DK111024) 合作伙伴支持，提出 利用和扩展正在进行的 RADx-UP 资助的 PEACH 项目 (P30DK111024)，设计和 通过手机提供的行为提示来评估基于家庭的 COVID-19 测试计划 在“An 通过行为助推改善 COVID-19 检测的家庭检测自适应干预试验 以及糖尿病患者的预防。” COVID-19 检测仍然是 了解和管理 COVID-19 大流行。佐治亚州面临多项挑战 COVID-19 管理包括疫苗接种率低、社区卫生合作伙伴过度扩张 管理 COVID-19 检测和疫苗接种，减少 COVID-19 检测数量和大量人口 风险较高，包括患有糖尿病或有患糖尿病风险的人、社会经济水平较低的个人，以及 非裔美国人/黑人和拉丁裔社区。在 PEACH2 项目中，我们建议利用社区 PEACH 项目的一部分建立并扩大了合作伙伴关系，以收集有关 COVID-19 的更多信息 测试，特别关注家庭测试解决方案（目标 1），使用定量（扩展 作为 PEACH 项目的一部分已经进行的后续调查）和定性（深入访谈） 100 名社区成员、主要利益相关者和社区合作伙伴）方法。该数据以及 PEACH 项目和乔治亚州 CEAL (1OT2HL156812-01/16-312-0217571-66105L) 的调查结果将用于 开发短信、行为提示以促进持续的 COVID-19 检测、报告和预防 行为，包括针对参与者的种族/民族、性别、年龄、疫苗接种状况和测试的疫苗接种 历史。然后，我们将评估（目标 2a）家庭测试平台的采用、使用和观点（提供 为每个家庭成员提供单一家庭 COVID-19 检测试剂盒，通过在线收集检测结果 报告系统，以及通过短信提供的有针对性的行为推动）在随机社区中- 通过与以下机构合作，针对受糖尿病影响的个体进行适应性干预试验（n=600）： 社区合作伙伴网站（基于信仰和社区的组织、Grady 糖尿病诊所、COVID-19 社区检测和疫苗分发站点）。我们还将评估（目标 2b）家庭测试平台如何 影响研究参与者和家庭成员的疫苗接种和犹豫。这项研究将建立在 通过 PEACH 项目建立的成功的社区学术伙伴关系，以进一步促进新冠病毒 19 在乔治亚州最脆弱的社区进行测试。吸取的教训可以传播给其他人 高危社区，并可进行调整以促进针对其他情况的家庭检测。