Administrative, Biostatistics, and Management Core

行政、生物统计和管理核心

• 批准号: 10447076
• 负责人: Giulio Maria Pasinetti
• 金额: $ 22.29万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10447076
• 关键词: Behavioral; Biological; Biometry; Botanical dietary supplements; resilience

Summary/Abstract The Administrative - Biostatistics/Data Management Core A of this Botanical Dietary Supplement Research Center (BDSRC) has a two tier plan. The Administrative Tier I Plan Component is divided into three broad categories: scientific, academic, and organizational. The components of the administrative core will provide the day-to-day management of the BDSRC and will facilitate interactions within and between the participating research groups at the Icahn School of Medicine at Mount Sinai and the external participating institutions. The organizational support provided by the Administrative Tier I Plan Component of this Core will operate through three “Work Groups” and will manage all administrative issues of the BDSRC, including scientific affairs, contractual agreements, allocation of funds/fiscal issues, personnel related issues, and fostering of new research. Overall the Work Groups in the Administrative Tier I Plan Component will be regulated by an Internal Steering Committee (ISC) composed of Research Project and Core Leaders to assess research progress and determine whether research goals are being met. The Administrative Tier I Plan Component of Core A will also be responsible for the creation and management of an External Advisory Committee (EAC) designed to provide oversight and assist the PD/PIs in making scientific and administrative decisions. In parallel, the Biostatistics/Data Management Tier II Plan Component is organized into one Work Group: Biostatistics and Data Management Work Group, which provide statistical support for all BDSRC Research Projects and Cores. While all of the BDSRC investigators are well versed in the statistical approaches that are applicable to their specific hypotheses and projects, Core A will provide statistical expertise, state-of-the-art analysis, and storage for all data sets, allowing integration of each Project's data with the data derived from the other Projects. The Tier II Plan Component has access to a data warehouse system that has recently been developed within Mount Sinai's Scientific Computing facility. This system will be available to each Research Project and Core for data integration/storage and data query through web interface. The integration of cross-project data for statistical analysis will not only be aided by the data management system described, but also through statistical testing of hypotheses, which will be an integral part of the development of each BDSRC Project from the time of its inception.

摘要/摘要 本次植物性膳食补充剂研究的行政生物统计/数据管理核心A 中心(BDSRC)有一个两级计划。管理第一级计划组件分为三大部分 类别：科学、学术和组织。行政核心的组成部分将提供 BDSRC的日常管理，并将促进参与的内部和之间的互动 西奈山伊坎医学院和外部参与机构的研究小组。这个 本核心的行政第一级计划部分提供的组织支持将通过 三个“工作组”，并将管理BDSRC的所有行政问题，包括科学事务， 合同协议、资金分配/财政问题、与人事有关的问题以及培养新的 研究。总体而言，行政第一级计划组成部分中的工作组将由内部 由研究项目和核心领导组成的指导委员会(ISC)，以评估研究进展和 确定是否达到了研究目标。核心A的行政第一级计划部分还将 负责创建和管理外部咨询委员会(EAC)，旨在 监督并协助PD/PIs作出科学和行政决策。同时， 生物统计/数据管理第二层计划组成部分被编入一个工作组：生物统计和 数据管理工作组，为所有BDSRC研究项目和核心提供统计支持。 虽然BDSRC的所有调查人员都精通适用于他们的 具体的假设和项目，核心A将提供统计专业知识、最先进的分析和存储 对于所有数据集，允许将每个项目的数据与从其他项目派生的数据进行集成。这个 第二层计划组件可以访问最近在装载中开发的数据仓库系统 西奈半岛的科学计算设施。该系统将可用于每个研究项目和核心数据 通过Web界面集成/存储和数据查询。整合跨项目数据进行统计 分析不仅将得到所描述的数据管理系统的帮助，还将通过以下统计测试得到帮助 假设，这将是每个BDSRC项目发展的一个组成部分，从它的时间开始 盗梦空间。