Core A: Administrative/Clinical/Bioinformatics Core

管理/临床/生物信息学核心（核心A）：摘要 行政/临床/生物信息学核心的总体目标是提供财政， 为每个项目提供行政、临床材料和数据访问、生物信息和统计支持 核心在这个项目中。 行政/临床/生物信息学核心具有行政和科学任务，将支持 这个PPG的目标和人员。这一核心将负责支持以下方面的所有行政工作： PPG，集中访问去识别的临床样本和相关临床数据库，并协调 PPG成员的生物统计学和信息学分析，包括微生物组成方面的协助 在PPG内对项目进行分析。行政职责包括协调所有NIH的互动， 包括组装和准备本申请，协调年度非竞争性更新相关 提交，以及所有其他NIH相关的互动。这一核心还将发挥统一和协调活动的作用 在计划项目参与者之间，包括每月会议的组织，以及所有内部和 外部审查。这个核心的另一个主要功能是促进和协调合作研究 通过使用共享的临床资源与临床数据库、生物信息学和 统计数据支持。最后，这个核心将有助于协调整个区域的微生物群落组成分析。 PPG。因此，这一核心将促进方案的组织和行政管理， 协调计划内的沟通，监控项目进度，确保有效使用 共享的资源核心，并提供关键的临床，数据库，生物信息学和统计支持。

Administrative/Clinical/Bioinformatics Core (Core A): Abstract The overall goals of the Administrative/Clinical/Bioinformatics Core are to provide fiscal, administrative, clinical material and data access, bioinformatic and statistics support to each Project and Core within this Program Project. The Administrative/Clinical/Bioinformatics Core has both administrative and scientific missions that will support the goals and personnel of this PPG. This core will be responsible for supporting all administrative efforts for the PPG, centralizing access to de-identified Clinical samples and related clinical databases, and coordinating biostatistics and informatics analyses for PPG members, including assistance in microbial composition analyses for the Projects within the PPG. Administrative duties include coordination of all NIH interactions, including assembly and preparation of this application, coordination of annual non-competitive renewal related submissions, and all other NIH related interactions. This core will also function to unify and coordinate activities amongst the Program Project participants, including organization of monthly meetings, and all internal and external reviews. Another major function of this core will be to foster and coordinate collaborative research activities within the PPG through use of shared clinical resources with clinical database, bioinformatics and statistics support. Finally, this core will help coordinate microbial community composition analyses across the PPG. Thus, this core will facilitate the organizational and administrative management of the Program, orchestrating communication within the Program, monitoring of progress in the Projects, ensuring effective use of the shared resource cores, and provide key clinical, database, bioinformatics and statistical support.