Translational Pathology

转化病理学

• 批准号: 10447609
• 负责人: Wei Jiang
• 金额: $ 34.32万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-06-22 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10447609
• 关键词: Accreditation; Acetone; Address; Alcohols; Automation; Biological Sciences; Biological Specimen Banks; Biomedical Research; Biometry; Cancer Center; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Consultations; Coupled; Data; Doctor of Philosophy; Faculty; Fixatives; Formaldehyde; Freezing; Funding; Future; Genomics; Genomics Shared Resource; Goals; Hematologic Neoplasms; Histology; Histopathology; Image Analysis; Immune; Informatics; Laboratories; Leadership; Malignant Neoplasms; Mission; Molecular; Oncology; Pathology; Research; Resource Sharing; Resources; Sampling; Services; Specimen; Strategic Planning; Technology; Tissue Banks; Tissue Microarray; Tissue Sample; Tissues; Translational Research; Yang; anticancer research; base; biobank; cancer genomics; cancer subtypes; companion diagnostics; data sharing; data warehouse; digital pathology; experience; informatics shared resource; informatics tool; laser capture microdissection; member; novel; operation; programs; recruit

TPSR Summary The mission of the Sidney Kimmel Cancer Center Translational Pathology Shared Resource (TPSR) is to serve as a biomedical research resource supporting novel cancer research for the SKCC's basic, clinical, and translational members. The TPSR provides immediate, single-portal access to pathology and informatics faculty expertise and technical support, including a comprehensive range of high-quality pathology and informatics services coupled with critical access to unique banked tissue collections. The TPSR was founded in 2000 and has been continuously funded by the NCI since 2001. The former Informatics Shared Resource (ISR) was integrated into the TPSR during the current project period, due to the close working relationship and mutual focus of informatics with pathology services. Stephen Peiper, MD, oversees the combined Shared Resource. Wei Jiang, MD, PhD, and Haifeng Yang, PhD, serve as Pathology Co-Directors under the direction of Dr. Peiper. Zhijiu Zhong, MD, MS, is an experienced facility manager responsible for the day-to-day operation of the TPSR. The TPSR has dedicated laboratory space in the centrally located Bluemle Life Sciences Building (BLSB). In addition, there is connecting office space for consultation on histology and informatics needs. Current TPSR goals include: 1) Provide data, specimens, and technology to enhance all aspects of oncology research; 2) Offer a full range of exceptional histopathology services: IHC (including multi- parameter), ISH, automation, laser capture microdissection, tissue array creation, and digital pathology with high res image analysis; 3) Give access to a CAP-accredited biorepository; 4) Provide biomedical research informatics tools for facile interrogation of a well-developed data warehouse.

TPSR总结 Sidney Kimmel癌症中心转化病理学共享资源（TPSR）的使命是 作为生物医学研究资源，支持SKCC的基础，临床和 翻译成员TPSR提供了对病理学和信息学的直接、单一门户访问 教师的专业知识和技术支持，包括全面的高质量病理学和 信息服务加上关键访问独特的库存组织收藏。TPSR成立于 自2001年以来一直由NCI资助。信息共享资源Informatics Shared Resource (ISR)由于密切的工作关系， 信息学与病理学服务的共同重点。斯蒂芬·佩珀，医学博士，负责监督合并后的共享 Resource. Wei Jiang，MD，PhD和Haifeng Yang，PhD担任指导下的病理学联合主任 佩珀博士的Zhijiu Zhong，MD，MS，是一位经验丰富的设施经理，负责日常工作， TPSR的运行。TPSR在位于市中心的Bluemle Life拥有专门的实验室空间 科学大楼（BLSB）。此外，还有连接的办公空间，用于组织学咨询， 信息需要。目前TPSR的目标包括：1）提供数据，标本和技术，以提高所有 肿瘤学研究的各个方面; 2）提供全方位的卓越组织病理学服务：IHC（包括多项 参数），ISH，自动化，激光捕获显微切割，组织阵列创建和数字病理学， 高分辨率图像分析; 3）获得CAP认证的生物储存库; 4）提供生物医学研究 信息学工具，用于方便地查询一个开发良好的数据仓库。