San Diego Resource Center for advancing Alzheimer's Research in Minority Seniors (ARMS)

项目摘要/摘要 迫切需要对代表不足的科学家进行有指导的培训，以研究少数民族 阿尔茨海默病和相关痴呆(ADRD)。为了解决研究和资源方面的差距， 拟议的圣地亚哥资源中心(SDRC)用于促进少数族裔老年人的阿尔茨海默氏症研究 (ARMS)旨在确定拉丁裔科学家和其他来自代表性不足背景的人是否致力于 支持拉丁裔ADRD研究，并支持他们成为独立的职业科学家。我们的建议 中心将专注于拉丁裔阿尔茨海默病和相关痴呆症的跨学科研究 (ADRD)阐明生物、行为、社会文化和环境因素在 拉丁裔ADRD的病因和转归。 SDRC-ARMS是加州大学圣地亚哥分校(UCSD)和圣地亚哥分校合作的项目 州立大学(SDSU)。这一合作利用了两家机构的优势：加州大学圣地亚哥分校在 行为、社会文化、系统生物学和多层组学，以了解拉丁裔和 其他人口和圣地亚哥州立大学作为研究多产的拉美裔服务机构的优势 公共卫生和心理学方面的课程，以及推动拉美裔职业生涯的丰富经验。这个 国家发改委-ARMS的综合资源提供了新的和独特的跨学科研究培训机会 从长凳到床边，再到社区，加速科学发现，改善大脑健康 拉美裔美国人。 国家发改委-ARMS将由四名首席调查员领导，每个校区两名：摩尔博士(加州大学圣地亚哥分校- 老年病学)、González(UCSD-神经科学)、Gilbert(SDSU-心理学)和Elder(SDSU/UCSD-公共 健康)。这四个PI具有互补的技能，并使用 团队科学模型。国家发改委-ARMS包括三个核心：行政、研究教育和 分析。我们的意图是，发改委-ARMS及其核心由不同类型的调查人员组成 关于他们的机构背景、学科以及研究和培训技能。这种多样性将 提高发改委-ARMS在发展多样化劳动力方面的有效性，以促进在以下方面的进展 拉丁裔ADRD。

PROJECT SUMMARY/ABSTRACT There is an urgent need for mentored training of underrepresented scientists in research on minorities with Alzheimer’s disease and related dementias (ADRD). To address the gap in research and resources, the proposed San Diego Resource Center (SDRC) for advancing Alzheimer’s Research in Minority Seniors (ARMS) aims to identify Latino scientists and others from underrepresented backgrounds who are committed to Latino ADRD research, and to support them in becoming independent career scientists. Our proposed center will focus on transdisciplinary research on Latino Alzheimer’s Disease and Related Dementias (ADRD) to illuminate the role of biological, behavioral, sociocultural and environmental factors in the etiology and outcomes of Latino ADRD. The SDRC-ARMS is a collaboration between the University of California, San Diego (UCSD) and San Diego State University (SDSU). This collaboration leverages both institutions’ strengths: UCSD’s strength in behavioral, sociocultural, systems biology, and multi-layered –omics to understanding ADRD in Latinos and other populations and SDSU’s strengths as a research-prolific Hispanic Serving Institution with robust programs in public health and psychology and vast experience in advancing the careers of Latinos. The SDRC-ARMS’ combined resources provide new and unique transdisciplinary research training opportunities from the bench, to the bedside, and to the community to accelerate scientific discoveries for better brain health of Latinos. The SDRC-ARMS will be led by four Principal Investigators (PI), two at each campus: Dr. Moore (UCSD- Geriatrics), González (UCSD-Neurosciences), Gilbert (SDSU-Psychology) and Elder (SDSU/UCSD-Public Health). The four PIs have complementary skills and have collaborated to develop this application using the team science model. The SDRC-ARMS includes three cores: Administrative, Research Education, and Analysis. It is our intention that the SDRC-ARMS and its Cores be composed of investigators who are diverse with respect to their institutional affiliations, disciplines, and research and training skills. This diversity will increase the SDRC-ARMS‘ effectiveness in developing a diverse workforce that can promote advances in Latino ADRD.