San Diego Resource Center for advancing Alzheimer's Research in Minority Seniors (ARMS)

项目概要/摘要 迫切需要对从事少数群体研究的人数不足的科学家进行指导培训， 阿尔茨海默病和相关痴呆症（ADRD）。为了解决研究和资源方面的差距， 建议圣地亚哥资源中心（SDRC）推进老年痴呆症在少数民族的研究 （ARMS）旨在确定拉丁裔科学家和其他来自代表性不足的背景谁致力于 拉丁裔ADRD研究，并支持他们成为独立的职业科学家。我们提出的 该中心将专注于拉丁美洲阿尔茨海默病和相关痴呆症的跨学科研究 （ADRD）阐明生物，行为，社会文化和环境因素在 拉丁裔ADRD的病因和结局。 SDRC-ARMS是加州大学圣地亚哥分校（UCSD）和圣地亚哥大学之间的合作项目 州立大学。这种合作利用了两个机构的优势：UCSD的优势， 行为，社会文化，系统生物学和多层组学，以了解拉丁美洲人的ADRD， 其他人口和SDSU的优势，作为一个研究多产的西班牙裔服务机构与强大的 公共卫生和心理学课程以及在推进拉丁美洲人职业生涯方面的丰富经验。的 SDRC-ARMS的综合资源提供了新的和独特的跨学科研究培训机会 从实验室，到床边，再到社区，加速科学发现，以改善大脑健康。 拉丁裔。 SDRC-ARMS将由四名首席研究员（PI）领导，每个校区两名：摩尔博士（UCSD- 老年医学），冈萨雷斯（UCSD神经科学），吉尔伯特（SDSU心理学）和老年人（SDSU/UCSD公共 健康）。这四个PI具有互补的技能，并合作使用 团队科学模型SDRC-ARMS包括三个核心：行政，研究教育和 分析.我们的意图是SDRC-ARMS及其核心由不同的研究人员组成 在机构隶属关系、学科以及研究和培训技能方面。这种多样性将 提高SDRC-ARMS在发展多样化劳动力方面的有效性， 拉丁裔ADRD。

PROJECT SUMMARY/ABSTRACT There is an urgent need for mentored training of underrepresented scientists in research on minorities with Alzheimer’s disease and related dementias (ADRD). To address the gap in research and resources, the proposed San Diego Resource Center (SDRC) for advancing Alzheimer’s Research in Minority Seniors (ARMS) aims to identify Latino scientists and others from underrepresented backgrounds who are committed to Latino ADRD research, and to support them in becoming independent career scientists. Our proposed center will focus on transdisciplinary research on Latino Alzheimer’s Disease and Related Dementias (ADRD) to illuminate the role of biological, behavioral, sociocultural and environmental factors in the etiology and outcomes of Latino ADRD. The SDRC-ARMS is a collaboration between the University of California, San Diego (UCSD) and San Diego State University (SDSU). This collaboration leverages both institutions’ strengths: UCSD’s strength in behavioral, sociocultural, systems biology, and multi-layered –omics to understanding ADRD in Latinos and other populations and SDSU’s strengths as a research-prolific Hispanic Serving Institution with robust programs in public health and psychology and vast experience in advancing the careers of Latinos. The SDRC-ARMS’ combined resources provide new and unique transdisciplinary research training opportunities from the bench, to the bedside, and to the community to accelerate scientific discoveries for better brain health of Latinos. The SDRC-ARMS will be led by four Principal Investigators (PI), two at each campus: Dr. Moore (UCSD- Geriatrics), González (UCSD-Neurosciences), Gilbert (SDSU-Psychology) and Elder (SDSU/UCSD-Public Health). The four PIs have complementary skills and have collaborated to develop this application using the team science model. The SDRC-ARMS includes three cores: Administrative, Research Education, and Analysis. It is our intention that the SDRC-ARMS and its Cores be composed of investigators who are diverse with respect to their institutional affiliations, disciplines, and research and training skills. This diversity will increase the SDRC-ARMS‘ effectiveness in developing a diverse workforce that can promote advances in Latino ADRD.