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Increasing the health equity and population-level impact of a digital therapeutic for smokers with psychiatric illness

提高数字疗法对患有精神疾病的吸烟者的健康公平性和人口影响

基本信息

批准号：
10457176
负责人：
Roger Vilardaga
金额：
$ 12.12万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-04-01 至 2027-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10457176
关键词：
Abstinence Address Adopted Adoption Affect Ancillary Study Area Award Black Populations Black race Characteristics Cigarette Clinic Clinical Clinical Investigator Clinical Trials Collaborations Communities Control Groups Counseling Data Data Set Development Devices Drug usage Effectiveness Enrollment Epidemiology Future Goals Health Health Services Accessibility Independent Scientist Award Individual Interview K-Series Research Career Programs Laboratories Latino Latino Population Learning Life Experience Link Literature Maintenance Marketing Measures Mental disorders Mentors Mentorship Methodology Methods Minority Modeling Not Hispanic or Latino Outcome Parents Patient Representative Patients Population Program Evaluation Protocols documentation Quality of life Reach Effectiveness Adoption Implementation and Maintenance Recommendation Research Research Design Research Personnel Sampling Scientist Smoker Smoking Socioeconomic Factors Surveys Technology Transfer Testing Therapeutic Intervention Therapeutic Uses Time Tobacco Control Research Tobacco Use Disorder Tobacco use Training Translating Voice Work addiction base behavioral health community consultation cost effectiveness design digital digital intervention digital treatment efficacy evaluation efficacy testing efficacy trial ethnic minority experience health equity health inequalities implementation evaluation implementation facilitators implementation science informant novel outreach population health pragmatic trial programs psychological distress quitline racial and ethnic racial minority racism recruit scale up severe mental illness smoking cessation trial design user centered design

项目摘要

PROJECT ABSTRACT The goal of this Independent Scientist Award (K02) is to seek five years of training and protected time to enable and expand the work of a newly established independent investigator. The candidate’s laboratory, the Access to Behavioral Health for All (ABHA) Lab, is supported by a recent R01 (Parent Study; DA037276; March 2020-2025) that will evaluate the efficacy of a novel digital therapeutic (DTx) for smoking cessation tailored to patients with serious mental illness. The candidate’s research to date has focused on the development of DTx using user-centered design research, and the subsequent testing of their efficacy using clinical trials methodology. However, efficacy trials do not always translate into real-world practice, nor are tested treatments always adopted by racial and ethnic minorities. This gap is well documented in the implementation science literature. A recent longitudinal epidemiological survey (N=40,181) showed that while the smoking rates of Non-Hispanic Whites with serious psychological distress significantly declined over the last decade, no significant declines occurred among their Black and Latino counterparts. This data accentuates the critical need to develop DTx that have an equitable population health impact. Therefore, the five years of protected time provided by this Independent Scientist Award will fundamentally enhance the candidate’s current program of research by providing formal training and contact with expert collaborators in the following key areas: (1) health equity and participatory research, (2) implementation science, and (3) DTx’s oversight, marketing, and dissemination. The award will also support a convergent mixed-methods Ancillary Study based on the RE-AIM framework, that will examine health equity and implementation science outcomes in the Parent Study. This Independent Scientist Award will provide the necessary research experience and network of collaborators to scale up widespread dissemination of DTx addressing the systemic challenges of racial/ethnic minorities with tobacco use disorder and serious mental illness. Along with the planned collaborations with national experts in each of the key training domains, this award will establish the conditions to pursue and maintain this program of research in the future by protecting the candidate’s time from clinical responsibilities. In the short term, the award will generate preliminary data to inform the design of a large pragmatic trial that will evaluate equitable dissemination of DTx for smoking cessation in patients with serious mental illness. In the long term the award will generate a new body of research rigorously examining racial and ethnic inequities in DTx for addiction treatment, a new model for the equitable implementation and technology transfer of DTx among racial/ethnic minorities, and mentoring opportunities for diverse junior scientists that will extend the impact of this work beyond the candidate’s own program of research.

项目摘要