Randomized Controlled Trial of a Novel Smoking Cessation Application Tailored to Individuals with Serious Mental Illness

针对严重精神疾病患者的新型戒烟应用程序的随机对照试验

基本信息

  • 批准号:
    10538646
  • 负责人:
  • 金额:
    $ 64.56万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2020
  • 资助国家:
    美国
  • 起止时间:
    2020-03-15 至 2024-12-31
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY/ABSTRACT Tobacco use remains at alarming high rates amongst individuals with serious mental illness, such as schizophrenia spectrum, bipolar, and recurring depressive disorders. Smoking tobacco is the number one preventable cause of death in this population, shortening the lifespan of adults with serious mental illness by 25 years and contributing to $317 billion in healthcare expenditures and indirect loss of earnings and disability benefits. Novel and effective models to deliver wider-reaching smoking cessation interventions to individuals with serious mental illness are highly needed and indicated as a priority for NIH. Mobile apps are a promising method to deliver smoking cessation treatments to people with serious mental illness. Despite numerous apps available to use for people with serious mental illness, our feasibility research has demonstrated that using these apps presents daunting challenges for this population. Based on this work, we developed Learn to Quit, a user-centered smoking cessation app tailored to the needs of individuals with serious mental illness. The app’s main active ingredient is a novel behavioral treatment that has shown promise as a smoking cessation intervention -- Acceptance and Commitment Therapy. The app provides education about the use of nicotine replacement therapy and recommendations from US Clinical Practice Guidelines to ensure alignment with best clinical practices. In a recent pilot randomized controlled trial (R00 DA037276), comparing Learn to Quit versus NCI’s QuitGuide, we demonstrated: (1) high recruitment and retention rates, (2) high levels of user engagement with Learn to Quit, (3) an effective method to conduct a large multi-site randomized controlled trial, and (4) promising cessation outcomes. While this developmental work provides initial evidence of Learn to Quit’s usability, feasibility, and preliminary efficacy, a large scale randomized controlled trial is needed to test its efficacy in a representative sample of patients with serious mental illness. Therefore, the proposed study will: (1) employ a randomized parallel arm design to compare the efficacy of Learn to Quit vs. NCI’s QuitGuide, (2) use rigorous methods to evaluate mediators of app engagement and app efficacy, and (3) examine the cost-effectiveness of Learn to Quit compared to a non-tailored app designed for the general population. The study addresses a serious problem -- high smoking rates among people with serious mental illness -- and proposes to test the efficacy of an easily-accessible smoking cessation intervention, using technology with the potential for high population-level reach.
项目总结/文摘

项目成果

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Roger Vilardaga其他文献

Roger Vilardaga的其他文献

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{{ truncateString('Roger Vilardaga', 18)}}的其他基金

Increasing the health equity and population-level impact of a digital therapeutic for smokers with psychiatric illness
提高数字疗法对患有精神疾病的吸烟者的健康公平性和人口影响
  • 批准号:
    10597126
  • 财政年份:
    2022
  • 资助金额:
    $ 64.56万
  • 项目类别:
Increasing the health equity and population-level impact of a digital therapeutic for smokers with psychiatric illness
提高数字疗法对患有精神疾病的吸烟者的健康公平性和人口影响
  • 批准号:
    10457176
  • 财政年份:
    2022
  • 资助金额:
    $ 64.56万
  • 项目类别:
Randomized Controlled Trial of a Novel Smoking Cessation Application Tailored to Individuals with Serious Mental Illness
针对严重精神疾病患者的新型戒烟应用程序的随机对照试验
  • 批准号:
    10318201
  • 财政年份:
    2020
  • 资助金额:
    $ 64.56万
  • 项目类别:
Randomized Controlled Trial of a Novel Smoking Cessation Application Tailored to Individuals with Serious Mental Illness
针对严重精神疾病患者的新型戒烟应用程序的随机对照试验
  • 批准号:
    9885332
  • 财政年份:
    2020
  • 资助金额:
    $ 64.56万
  • 项目类别:
An Administrative Supplement to Increase the Recruitment Rates of R01 DA047301 a Pivotal Trial of a Novel Digital Therapeutic for Smoking Cessation in Psychiatric Populations
提高 R01 DA047301 招募率的行政补充 精神病人群戒烟新型数字疗法的关键试验
  • 批准号:
    10818811
  • 财政年份:
    2020
  • 资助金额:
    $ 64.56万
  • 项目类别:
Early-phase Studies of a Tailored Evidence-Based Smoking Cessation mHealth App for Persons Living with HIV
针对艾滋病毒感染者量身定制的循证戒烟 mHealth 应用程序的早期研究
  • 批准号:
    10016254
  • 财政年份:
    2019
  • 资助金额:
    $ 64.56万
  • 项目类别:
Innovative Smartphone Application for Quitting Smoking among Seriously Mentally III
用于戒烟的创新智能手机应用程序 III
  • 批准号:
    9326973
  • 财政年份:
    2016
  • 资助金额:
    $ 64.56万
  • 项目类别:
Innovative Smartphone Application for Quitting Smoking among Seriously Mentally I
用于认真戒烟的创新智能手机应用程序 I
  • 批准号:
    8677529
  • 财政年份:
    2014
  • 资助金额:
    $ 64.56万
  • 项目类别:

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