Administrative Supplement: The Midwest Center for Cryo-Electron Tomography
行政补充:中西部冷冻电子断层扫描中心
基本信息
- 批准号:10457095
- 负责人:
- 金额:$ 45.48万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-15 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:Administrative SupplementAdministratorBiochemistryBiological SciencesCarbonCell Culture TechniquesComplexComputersCryo-electron tomographyCryoelectron MicroscopyData CollectionDatabase Management SystemsDevelopmentDevicesDisciplineElectron MicroscopeElectron MicroscopyEnsureEquipmentFluorescenceFreezingGrantHuman ResourcesImageImage AnalysisIndividualInternationalIonsLaboratory cultureLight MicroscopeMethodsMidwestern United StatesMolecular BiologyOrganellesOrganismPostdoctoral FellowPreparationRecording of previous eventsResearchResearch PersonnelResourcesRobotRoleSamplingScanningScientistServicesSiteSpecimenStandardizationSystemTeacher Professional DevelopmentTechnologyTissuesTrainingTraining ActivityUnited States National Institutes of HealthUniversitiesValidationWisconsincomputerized data processingcryogenicsdata acquisitionevaporationexperienceimage processingimprovedinnovationinstrumentationmacromoleculematerials sciencememberoperationpreservationpressurepublic health relevancerecruitskillssmall moleculetechnology developmentvirtual
项目摘要
Modified Project Summary/Abstract Section
We propose to establish a National Service Network Hub for Cryo-Electron Tomography to be hosted in the Department of Biochemistry at the University of Wisconsin, Madison. The Midwest Center for Cryo-Electron Tomography (MCCET) will support investigators by providing access to well-trained staff and state-of-the-art equipment for (1) routine and advanced cryo-electron tomography (cryo-ET) specimen preparation, data collection, and computation; and (2) hands-on, remote, and virtual training in cryo-ET specimen preparation, data collection, and data processing and validation. MCCET operations will build on the Cryo-EM Research Center (CEMRC) established in the Department of Biochemistry at the University of Wisconsin, Madison. The University of Wisconsin, Madison has a long history of institutional commitment to electron microscopy, as well as the advancement of electron microscopy in both the biological and materials sciences. The ancillary equipment and major instrumentation to be housed in the MCCET will include: cell culture equipment, a fluorescence light microscope and micropatterning system, glow discharge devices, carbon evaporator, automated plunge freezer, high pressure freezer, cryo-ultramicrotome, a cryo-focused ion beam-scanning electron microscope (cryo-FIB-SEM), and a 300 kV TEM. Dr. Elizabeth R. Wright, the contact PI, has over twenty-years of cryo-EM experience including the development of new cryo-EM technologies and workflows along with directing and managing (cryo-)electron microscopy research resources. Drs. Marisa Otegui, Robert Kirchdoerfer, and Tim Grant bring complementary expertise in sample preservation and imaging of complex tissues, small molecules and organelles, imaging and computational technology development, as well as facility management. A center manager, a computer scientist/systems administrator, a project manager, cryo- ET training instructors, a computer scientist, and postdoctoral research associates will manage MCCET day-today operations and support users through the course of their projects from initial access, sample handling and preparation, sample validation, cryo-ET data collection and processing, and cross-training. Hub coordination activities with the NIH, network centers, and users will be managed by the PI, project manager, center manager, and computer scientist/systems administrator. The Midwest Center for Cryo-Electron Tomography (MCCET) will maintain a culture of innovation and technology development in cryo-ET to facilitate improvements to cryo-ET sample preparation, throughput, validation, and imaging. The MCCET will be a user-experience focused resource that will provide access and training to researchers across many disciplines.
修改的项目摘要/摘要部分
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
ELIZABETH R WRIGHT其他文献
ELIZABETH R WRIGHT的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('ELIZABETH R WRIGHT', 18)}}的其他基金
Administrative Supplement: The Midwest Center for Cryo-Electron Tomography
行政补充:中西部冷冻电子断层扫描中心
- 批准号:
10581217 - 财政年份:2020
- 资助金额:
$ 45.48万 - 项目类别:
The Midwest Center for Cryo-Electron Tomography
中西部冷冻电子断层扫描中心
- 批准号:
10054846 - 财政年份:2020
- 资助金额:
$ 45.48万 - 项目类别:
Administrative Supplement: The Midwest Center for Cryo-Electron Tomography
行政补充:中西部冷冻电子断层扫描中心
- 批准号:
10399898 - 财政年份:2020
- 资助金额:
$ 45.48万 - 项目类别:
Administrative Supplement 2: The Midwest Center for Cryo-Electron Tomography
行政补充文件 2:中西部冷冻电子断层扫描中心
- 批准号:
10824903 - 财政年份:2020
- 资助金额:
$ 45.48万 - 项目类别:
Administrative Supplement: The Midwest Center for Cryo-Electron Tomography
行政补充:中西部冷冻电子断层扫描中心
- 批准号:
10817476 - 财政年份:2020
- 资助金额:
$ 45.48万 - 项目类别:
Administrative Supplement: The Midwest Center for Cryo-Electron Tomography
行政补充:中西部冷冻电子断层扫描中心
- 批准号:
10648494 - 财政年份:2020
- 资助金额:
$ 45.48万 - 项目类别:
The Midwest Center for Cryo-Electron Tomography
中西部冷冻电子断层扫描中心
- 批准号:
10473714 - 财政年份:2020
- 资助金额:
$ 45.48万 - 项目类别:
The Midwest Center for Cryo-Electron Tomography
中西部冷冻电子断层扫描中心
- 批准号:
10263230 - 财政年份:2020
- 资助金额:
$ 45.48万 - 项目类别:
Structure and function of prokaryotic appendages by cryo-electron tomography
冷冻电子断层扫描原核附属物的结构和功能
- 批准号:
8421785 - 财政年份:2013
- 资助金额:
$ 45.48万 - 项目类别:
Structural studies of respiratory syncytial virus
呼吸道合胞病毒的结构研究
- 批准号:
8512145 - 财政年份:2013
- 资助金额:
$ 45.48万 - 项目类别:
相似海外基金
EAGER: Toward a Decentralized Cross-administrator Zone Management System: Policy and Technology
EAGER:走向去中心化的跨管理员区域管理系统:政策和技术
- 批准号:
2331936 - 财政年份:2023
- 资助金额:
$ 45.48万 - 项目类别:
Standard Grant
COLLABORATIVE RESEARCH: Social Influence in Eyewitness Identification Procedures: Do Blind Administrator Behaviors Magnify the Effects of Suspect Bias?
合作研究:目击者识别程序中的社会影响:盲目的管理员行为是否会放大嫌疑人偏见的影响?
- 批准号:
2043230 - 财政年份:2021
- 资助金额:
$ 45.48万 - 项目类别:
Continuing Grant
COLLABORATIVE RESEARCH: Social Influence in Eyewitness Identification Procedures: Do Blind Administrator Behaviors Magnify the Effects of Suspect Bias?
合作研究:目击者识别程序中的社会影响:盲目的管理员行为是否会放大嫌疑人偏见的影响?
- 批准号:
2043334 - 财政年份:2021
- 资助金额:
$ 45.48万 - 项目类别:
Continuing Grant
Making of the base for patient safety management skill of visiting nurse administrator by the web conference system
利用网络会议系统构建出诊护士管理者患者安全管理技能基础
- 批准号:
19K10768 - 财政年份:2019
- 资助金额:
$ 45.48万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of the nursing administrator training program to improve leadership behavior focused on emotional intelligence
制定护理管理人员培训计划,以改善以情商为重点的领导行为
- 批准号:
18K17464 - 财政年份:2018
- 资助金额:
$ 45.48万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Automated Network Management that Dynamically Reflects Administrator Intent
动态反映管理员意图的自动化网络管理
- 批准号:
18K18038 - 财政年份:2018
- 资助金额:
$ 45.48万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Administrator support perceived as useful for professional growth by novice psychiatric home-visit nursing staff
新手精神科家访护理人员认为管理员支持对专业成长有用
- 批准号:
17H07005 - 财政年份:2017
- 资助金额:
$ 45.48万 - 项目类别:
Grant-in-Aid for Research Activity Start-up
The Facts and Problems on Management of Public Museums: Validation of Designated Administrator System
公共博物馆管理的事实与问题:指定管理员制度的验证
- 批准号:
17K01212 - 财政年份:2017
- 资助金额:
$ 45.48万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
A Study on Transformation of the School Administrator Preparation and Evaluation System in the United States
美国学校管理人员培养与评价体系转型研究
- 批准号:
26780449 - 财政年份:2014
- 资助金额:
$ 45.48万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
The Family Court's Supervision of Property Administrator
家庭法院对财产管理人的监督
- 批准号:
26380108 - 财政年份:2014
- 资助金额:
$ 45.48万 - 项目类别:
Grant-in-Aid for Scientific Research (C)