Ejaculate-mediated paternal effects on offspring fitness

射精介导的父系对后代健康的影响

• 批准号: DP210100468
• 负责人: Prof Jonathan Evans
• 金额: $ 31.7万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-02-01 至 2025-01-01
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210100468
• 关键词: Ejaculate; mediated; paternal; effects; offspring

This project aims to unravel the evolutionary importance of ejaculate-mediated paternal effects, through which paternal lifestyle factors, such as diet and exposure to toxicants, influence offspring growth and health independently of genes. By identifying the molecular mechanisms underlying these non-genetic sources of inheritance, their adaptive value, and their potential to fuel evolutionary change, the project expects to generate new knowledge that will be relevant across the biological, medical and agricultural sectors. Expected outcomes and benefits include building institutional and interdisciplinary collaborations and the development of tools to understand the evolutionary impacts of paternal lifestyle choices for offspring traits.

该项目旨在揭示射精介导的父亲效应的进化重要性，通过这种作用，父亲的生活方式因素，如饮食和接触有毒物质，独立于基因影响后代的生长和健康。通过确定这些非遗传遗传来源的分子机制、其适应价值及其推动进化变化的潜力，该项目预计将产生与生物、医学和农业部门相关的新知识。预期的成果和好处包括建立机构和跨学科的合作，并开发工具，以了解父亲的生活方式选择对后代性状的进化影响。