Understanding disease resistance gene evolution across the Brassicaceae

了解十字花科的抗病基因进化

• 批准号: DP210100296
• 负责人: Prof Jacqueline Batley
• 金额: $ 46.39万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-06-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210100296
• 关键词: Understanding; disease; resistance; gene; evolution

Pan genomes represent the diversity of a species, including structural and sequence variation, which cannot be provided by a reference genome alone. In this project we will characterise resistance gene diversity across the Brassicaceae pan genomes. Through comparison with resistance gene diversity in cultivated Brassica species we will understand selection underlying resistance gene evolution in wild species and subsequent domestication and breeding. Knowledge on how variation affects disease susceptibility, especially to the devastating fungal pathogen blackleg, and contributes to phenotypic variation, will lead to improved plant protection strategies and increased crop resilience.

PAN基因组代表一个物种的多样性，包括结构和序列变异，这是仅靠参考基因组不能提供的。在这个项目中，我们将描述十字花科PAN基因组中抗性基因的多样性。通过与栽培种抗病基因多样性的比较，我们将了解野生种抗病基因的选择、进化以及随后的驯化和育种。了解变异如何影响疾病的敏感性，特别是对毁灭性的真菌病原菌黑腿的敏感性，并有助于表型变异，将有助于改进植物保护策略，提高作物的抗逆性。