Understanding disease resistance gene evolution across the Brassicaceae

了解十字花科的抗病基因进化

• 批准号: DP210100296
• 负责人: Prof Jacqueline Batley
• 金额: $ 46.39万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-06-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210100296
• 关键词: Understanding; disease; resistance; gene; evolution

Pan genomes represent the diversity of a species, including structural and sequence variation, which cannot be provided by a reference genome alone. In this project we will characterise resistance gene diversity across the Brassicaceae pan genomes. Through comparison with resistance gene diversity in cultivated Brassica species we will understand selection underlying resistance gene evolution in wild species and subsequent domestication and breeding. Knowledge on how variation affects disease susceptibility, especially to the devastating fungal pathogen blackleg, and contributes to phenotypic variation, will lead to improved plant protection strategies and increased crop resilience.

PAN基因组代表一个物种的多样性，包括结构和序列变异，仅参考基因组不能提供。在这个项目中，我们将表征整个Brassicaceae PAN基因组中的抗性基因多样性。通过与栽培木制物种中的抗性基因多样性进行比较，我们将了解野生物种中的抗性基因进化的选择以及随后的驯化和繁殖。关于变异如何影响疾病易感性的知识，尤其是对毁灭性真菌病原体黑质的易感性，并有助于表型变异，将导致植物保护策略改善并提高作物弹性。