Sex and Gender Analysis Resource Core

流感免疫力(SADII)的性别和年龄差异及性别分析 资源核心摘要 SADII性别和性别分析核心将由Rosemary Morgan博士和Abdul Bachani博士领导，并将 为下列人类研究项目(即SADII研究项目1和2)提供分析支助 SADII的分数。核心将为SADII使用的数据收集工具和方法提供投入 研究项目1和2，除提供支助外，更好地为相关的性别和性别分析提供信息 对数据进行定性和定量分析，以检查和理解不同和重叠的数据 性别和性别的贡献，以及它们与其他社会阶层(如种族)的交集，对疫苗的贡献- 年轻人和老年人的诱导免疫反应、不良反应和结果。具体来说，我们将 探讨性别和性别差异：(1)流感疫苗接受度(SADII研究项目2)；(2) 免疫反应(SADII研究项目1-2)；和(3)接种疫苗的不良反应(SADII研究 项目1-2)。我们将提供临床和免疫学数据的量化分析，以探索性别 疫苗诱导的免疫反应的差异，包括性别如何与其他社会阶层相交， 例如年龄、种族和虚弱，以影响流感疫苗接种后的免疫反应和结果。 我们还将进行定量和定性的数据收集和分析，以探索性别差异 疫苗接受度、免疫反应和不良反应，以及性别与其他社会因素的交叉 影响流感后免疫反应和预后的分层因素，如年龄、种族和虚弱 接种疫苗。最后，我们将分析性和性别的相互作用，包括性和性别如何 与其他社会分层因素，如年龄、种族和脆弱程度相交，影响疫苗诱导的免疫 接种流感疫苗后的反应和结果。探索性和性别如何与其他 社会分层将使我们能够探索男性和女性之间的差异，以及 男性和女性在疫苗接受度、免疫反应和接种疫苗的不良反应方面。此外 为了支持SADII评分项目，性别和性别分析资源核心还将提供 对公共卫生和临床研究人员感兴趣的性和性别定性和性别分析的服务 定量研究，目前在约翰霍普金斯大学是不可用的。

SEX AND AGE DIFFERENCES IN IMMUNITY TO INFLUENZA (SADII) SEX AND GENDER ANALYSIS RESOURCE CORE SUMMARY The SADII Sex and Gender Analysis Core will be led by Drs. Rosemary Morgan and Abdul Bachani and will provide analytic support to the human research projects (i.e., SADII Research Projects 1 and 2) included under the SADII SCORE. The Core will provide input into the data collection tools and approaches utilized in SADII Research Projects 1 and 2 to better inform relevant sex and gender analysis, in addition to providing support for both qualitative and quantitative analyses of data to examine and understand the distinct and overlapping contributions of sex and gender, and their intersection with other social stratifiers (e.g., race), to vaccine- induced immune responses, adverse reactions, and outcomes in young and aged adults. Specifically, we will explore sex and gender differences in: (1) influenza vaccine acceptance (SADII Research Project 2); (2) immune responses (SADII Research Projects 1-2); and (3) adverse reactions to vaccination (SADII Research Projects 1-2). We will provide quantitative analysis of clinical and immunological data to explore sex differences in vaccine-induced immune responses, including how sex intersects with other social stratifiers, such as age, race, and frailty, to influence immune responses and outcomes following influenza vaccination. We also will perform quantitative and qualitative data collection and analysis to explore gender differences in vaccine acceptance, immune responses, and adverse reactions, and how gender intersects with other social stratifiers, such as age, race, and frailty, to influence immune responses and outcomes following influenza vaccination. Finally, we will offer analysis of the interaction of sex and gender, including how sex and gender intersect with other social stratifiers, such as age, race, and frailty, to influence vaccine-induced immune responses and outcomes following influenza vaccination. Exploring how sex and gender intersect with other social stratifiers will enable us to explore differences between men and women, as well as differences among men and women in vaccine acceptance, immune responses, and adverse reactions to vaccination. In addition to supporting the SADII SCORE projects, the Sex and Gender Analysis Resource Core will also provide services to public health and clinical researchers interested in sex and gender analysis of qualitative and quantitative research, which is currently not available at Johns Hopkins.