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中文摘要
翻译
抽象行政核心 这个临床研究核心中心的主要目标是促进有影响力的研究 在儿童风湿性和非炎症性肌肉骨骼疾病(PMSKD)中通过局部和 国家研究社区,专注于加强我们成熟的研究计划 在幼年特发性关节炎(JIA)、儿童期起病系统性红斑狼疮方面的专业知识 红斑狼疮(CSLE)和幼年型纤维肌痛(JFM)。行政机关的角色定位 核心(AC)将作为儿科的执行、协调和监督部分 肌肉骨骼和风湿病创新核心中心(PORTICO)将提高临床水平 PMSKD的研究。拟议的董事是赫敏·I·布伦纳,医学硕士MBA,以及 副主任是Susmita Kashikar-Zuck博士,既有知名的临床医生,也有资深的临床医生 研究人员。Portico的首席执行官和行政机构将由7名成员组成 执行委员会(EC),由Brunner博士和Kashikar-Zuck博士以及5个Highly 将担任研究所所长兼副主任/S的有成就的科学家 方法论核心和患者评估资源核心。欧盟委员会将由一名内部 咨询委员会、外部咨询委员会、试点和可行性研究委员会。这个 咨询委员会的具体目标是:(1)为高效率的 在PMSKD中进行和传播创新团队科学,(2)开发一个 促进地方和国家PMSKD跨学科临床研究的外展计划 以及(3)通过创建和管理试点项目提供测试新想法的机会&可行性 研究计划,以巩固Portico的目标。AC将负责集中 Porticos服务、创新和教育服务与 已经存在于辛辛那提儿童医院丰富的研究环境中, 辛辛那提大学医学院和国家资源和研究网络 交流领导层有很好的人脉。对于AC,我们已经建立了一个强大的领导层 计划,以及活动的沟通、管理和评估计划以及 Portico的资源。此外,房委会将管理外展计划,加强工作 研究界通过已建立的和早期的职业生涯支持新颖和创新的工作 研究人员推动PMSKD研究领域的发展。
英文摘要
ABSTRACT – ADMINISTRATIVE CORE The primary objective of this Core Center for Clinical Research is to promote impactful research in pediatric rheumatic and non-inflammatory musculoskeletal diseases (PMSKD) by the local and national Research Community with a focus on enhancing our well-established research programs and institutional expertise in juvenile idiopathic arthritis (JIA), childhood-onset systemic lupus erythematosus (cSLE) and juvenile-onset fibromyalgia (JFM). The role of the Administrative Core (AC) is to serve as the executive, coordinating and oversight component of the Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO) to enhance clinical research in PMSKD. The proposed Director is Hermine I Brunner, MD MSc MBA, and the Associate Director is Susmita Kashikar-Zuck, PhD, both well-established and senior clinical researchers. The chief executive & administrative body of PORTICO will be a 7-member Executive Committee (EC) composed of Drs. Brunner and Kashikar-Zuck and 5 highly accomplished scientists who will serve as the Director and Associate Director/s of the Methodology Core & Patient Assessment Resource Core. The EC will be supported by an Internal Advisory Committee, External Advisory Committee and Pilot and Feasibility study committee. The specific aims of the AC are (1) Provision of executive and scientific leadership for the efficient conduct and dissemination of innovative team science in PMSKD, (2) Development of an Outreach Program to promote interdisciplinary clinical research in PMSKD locally and nationally and (3) Provision of opportunities to test new ideas by creating and managing a Pilot & Feasibility Studies Program to fortify the goals of PORTICO. The AC will be responsible for focusing PORTICOs services, innovation and educational offerings to be complementary to those that already exist within the rich research environment within Cincinnati Children's Hospital and the University of Cincinnati College of Medicine and national resources and research networks to which the AC leadership is well connected. For the AC, we have developed a robust leadership plan, along with plans for communication, management and evaluation of the activities and resources of PORTICO. In addition, the AC will manage the outreach program, work to enhance the research community to support novel and innovative work by established and early career investigators to advance the field of PMSKD research.
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The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
  • 批准号:
    10435703
  • 项目类别:
  • 资助金额:
    $125.51万
  • 财政年份:
    2022
  • 负责人:
    Hermine I Brunner
  • 依托单位:
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
  • 批准号:
    10663270
  • 项目类别:
  • 资助金额:
    $119.6万
  • 财政年份:
    2022
  • 负责人:
    Hermine I Brunner
  • 依托单位:
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)
  • 批准号:
    10466931
  • 项目类别:
  • 资助金额:
    $67.88万
  • 财政年份:
    2019
  • 负责人:
    Hermine I Brunner
  • 依托单位:
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)
  • 批准号:
    10680547
  • 项目类别:
  • 资助金额:
    $65.99万
  • 财政年份:
    2019
  • 负责人:
    Hermine I Brunner
  • 依托单位:
海外基金