Administrative Core

行政核心

基本信息

  • 批准号:
    10680548
  • 负责人:
  • 金额:
    $ 19.09万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-09-16 至 2024-06-30
  • 项目状态:
    已结题

项目摘要

ABSTRACT – ADMINISTRATIVE CORE The primary objective of this Core Center for Clinical Research is to promote impactful research in pediatric rheumatic and non-inflammatory musculoskeletal diseases (PMSKD) by the local and national Research Community with a focus on enhancing our well-established research programs and institutional expertise in juvenile idiopathic arthritis (JIA), childhood-onset systemic lupus erythematosus (cSLE) and juvenile-onset fibromyalgia (JFM). The role of the Administrative Core (AC) is to serve as the executive, coordinating and oversight component of the Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO) to enhance clinical research in PMSKD. The proposed Director is Hermine I Brunner, MD MSc MBA, and the Associate Director is Susmita Kashikar-Zuck, PhD, both well-established and senior clinical researchers. The chief executive & administrative body of PORTICO will be a 7-member Executive Committee (EC) composed of Drs. Brunner and Kashikar-Zuck and 5 highly accomplished scientists who will serve as the Director and Associate Director/s of the Methodology Core & Patient Assessment Resource Core. The EC will be supported by an Internal Advisory Committee, External Advisory Committee and Pilot and Feasibility study committee. The specific aims of the AC are (1) Provision of executive and scientific leadership for the efficient conduct and dissemination of innovative team science in PMSKD, (2) Development of an Outreach Program to promote interdisciplinary clinical research in PMSKD locally and nationally and (3) Provision of opportunities to test new ideas by creating and managing a Pilot & Feasibility Studies Program to fortify the goals of PORTICO. The AC will be responsible for focusing PORTICOs services, innovation and educational offerings to be complementary to those that already exist within the rich research environment within Cincinnati Children's Hospital and the University of Cincinnati College of Medicine and national resources and research networks to which the AC leadership is well connected. For the AC, we have developed a robust leadership plan, along with plans for communication, management and evaluation of the activities and resources of PORTICO. In addition, the AC will manage the outreach program, work to enhance the research community to support novel and innovative work by established and early career investigators to advance the field of PMSKD research.
摘要-行政核心 该临床研究核心中心的主要目标是促进有影响力的研究 在儿科风湿性和非炎性肌肉骨骼疾病(PMSKD)中, 国家研究社区,重点是加强我们完善的研究计划 和机构的专门知识,在青少年特发性关节炎(JIA),儿童发病的系统性狼疮, 红斑性狼疮(cSLE)和青少年发作的纤维肌痛(JFM)。行政部门的作用 核心(AC)是儿科的执行、协调和监督组成部分。 肌肉骨骼和风湿病创新核心中心(PORTICO),以提高临床 研究PMSKD。拟议的董事是Hermine I Brunner,MD MSc MBA, 副主任是Susmita Kashikar-Zuck博士,既有成熟的临床经验,也有资深的临床经验。 研究人员PORTICO的首席执行官和行政机构将由7名成员组成 执行委员会(EC)由Brunner博士和Kashikar-Zuck博士以及5名高级管理人员组成。 有成就的科学家谁将担任主任和副主任/s的 方法学核心和患者评估资源核心。EC将由内部支持 咨询委员会、外部咨询委员会、试点和可行性研究委员会。的 AC的具体目标是(1)为有效的执行提供行政和科学领导 在PMSKD中进行和传播创新团队科学,(2)开发 推广计划,以促进跨学科的临床研究PMSKD本地和全国 和(3)通过创建和管理试点和可行性研究,提供测试新想法的机会 研究计划,以巩固PORTICO的目标。AC将负责聚焦 PORTICO的服务、创新和教育产品将与那些 已经存在于辛辛那提儿童医院和 辛辛那提大学医学院和国家资源和研究网络, AC的领导层关系很好对于AC,我们已经建立了一个强大的领导 计划,沿着活动的沟通、管理和评估计划, PORTICO的资源此外,AC将管理外展计划,努力加强 研究界通过建立和早期职业来支持新颖和创新的工作 研究人员推进PMSKD研究领域。

项目成果

期刊论文数量(0)
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Hermine I Brunner其他文献

Understanding the biology and use of anti-TNF agents in JIA – interim results
  • DOI:
    10.1186/1546-0096-10-s1-a48
  • 发表时间:
    2012-07-13
  • 期刊:
  • 影响因子:
    2.300
  • 作者:
    Daniel J Lovell;Steven P Spalding;Karen Onel;Beth S Gottlieb;Hermine I Brunner;Yukiko Kimura;Paula W Morris;Judyann C Olson;Anne Johnson;Edward H Giannini
  • 通讯作者:
    Edward H Giannini
Defining clinical remission and clinically inactive disease in juvenile systemic lupus erythematosus (jSLE)
  • DOI:
    10.1186/1546-0096-9-s1-o17
  • 发表时间:
    2011-09-14
  • 期刊:
  • 影响因子:
    2.300
  • 作者:
    Rina Mina;Laura Schanberg;Anne B Eberhard;Marisa Klein–Gitelman;Gloria Higgins;Karen Onel;Nora G Singer;Kathleen O’Neil;Lori Tucker;Deborah Levy;Wajeeha Yousaf;Shannen Nelson;Michael Beresford;Ruben Cuttica;Graciela Espada;Angelo Ravelli;Alberto Martini;Edward Giannini;Hermine I Brunner
  • 通讯作者:
    Hermine I Brunner
Achieving consensus on quality indicators (QI) for pediatric Systemic Lupus Erythematosus (pSLE)
  • DOI:
    10.1186/1546-0096-9-s1-p247
  • 发表时间:
    2011-09-14
  • 期刊:
  • 影响因子:
    2.300
  • 作者:
    Joshua Pendl;Matt Hollander;Shannen Nelson;Wajeeha Yousaf;Nicola Ruperto;Michael Beresford;Marisa Klein-Gitelman;Marilynn Punaro;Anne Stevens;Tadej Avcin;Graciela Espada;Tsz-Leung Lee;Yu-Lung Lau;Jennifer Huggins;Esi Morgan-DeWitt;Hermine I Brunner
  • 通讯作者:
    Hermine I Brunner

Hermine I Brunner的其他文献

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{{ truncateString('Hermine I Brunner', 18)}}的其他基金

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
小儿狼疮性肾炎吗替麦考酚酯 (PLUMM) 研究
  • 批准号:
    10435703
  • 财政年份:
    2022
  • 资助金额:
    $ 19.09万
  • 项目类别:
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
小儿狼疮性肾炎吗替麦考酚酯 (PLUMM) 研究
  • 批准号:
    10663270
  • 财政年份:
    2022
  • 资助金额:
    $ 19.09万
  • 项目类别:
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)
小儿肌肉骨骼
  • 批准号:
    10466931
  • 财政年份:
    2019
  • 资助金额:
    $ 19.09万
  • 项目类别:
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)
小儿肌肉骨骼
  • 批准号:
    10680547
  • 财政年份:
    2019
  • 资助金额:
    $ 19.09万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10245131
  • 财政年份:
    2019
  • 资助金额:
    $ 19.09万
  • 项目类别:
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)
小儿肌肉骨骼
  • 批准号:
    10019332
  • 财政年份:
    2019
  • 资助金额:
    $ 19.09万
  • 项目类别:
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)
小儿肌肉骨骼
  • 批准号:
    10245129
  • 财政年份:
    2019
  • 资助金额:
    $ 19.09万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10019355
  • 财政年份:
    2019
  • 资助金额:
    $ 19.09万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10466932
  • 财政年份:
    2019
  • 资助金额:
    $ 19.09万
  • 项目类别:
Optimization of Outcome Measures For Clinical Trials in Children with Lupus
狼疮儿童临床试验结果指标的优化
  • 批准号:
    8924907
  • 财政年份:
    2014
  • 资助金额:
    $ 19.09万
  • 项目类别:

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