Biostatistics, Epidemiology, and Research Design Core

生物统计学、流行病学和研究设计核心

• 批准号: 10466952
• 负责人: CHRISTOPHER H. SCHMID
• 金额: $ 58.46万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10466952
• 关键词: Address; Area; Bioinformatics; Biometry; Clinical; Clinical Research; Collaborations; Communities; Community Outreach; Community Participation; Conflict (Psychology); Consultations; Data; Data Analyses; Data Collection; Decision Making; Development; Diffusion; Discipline; Educational Models; Educational Technology; Educational process of instructing; Enrollment; Environment; Epidemiology; Foundations; Goals; Health; Health protection; Infrastructure; Institution; Investments; Lead; Learning; Link; Methods; Modality; Persons; Phase; Pilot Projects; Qualitative Research; Research; Research Design; Research Personnel; Research Support; Resources; Rhode Island; Schedule; Structure; Training; Training Support; Translational Research; Universities; Work; analytical method; analytical tool; biomedical informatics; community engagement; cyber infrastructure; design; epidemiology study; experience; faculty research; health data; improved; innovation; multidisciplinary; programs; satisfaction; tool; translational scientist; web portal; web site

ABSTRACT – BIOSTATISTICS, EPIDEMIOLOGY, AND RESEARCH DESIGN CORE The BERD Core has helped to transform clinical and translational research in Rhode Island during Phase I of Advance-CTR providing guidance in study design, data collection, data analysis, framing of results and drawing reasoned inferences. BERD has also provided training in research principles and a variety of essential tools. The result has been a markedly improved quality of research applications, increased diffusion of research support to young investigators, a high level of satisfaction and excitement in the research community, and a desire for even more support. In Phase II, the BERD Core will expand its support into new areas, using new modalities and reaching out to new audiences. We will work to connect the many isolated groups of analysts with whom we have connected who are embedded within Advance-CTR partners. Our goal is to evolve toward a sustainable infrastructure that meets the research needs of the entire state. By capitalizing on the existing resources of partner institutions, our efforts will help maximize the value of their existing investments as well as point to gaps in needs that can be filled through collaboration or expansion. Our centralized web portal already efficiently matches investigators to a highly qualified and diverse set of experts with long-term consultative experience and a reservoir of faculty research leaders skilled at teaching. We will expand consultative and training support, including adding a second Core Co-Lead, for designing and analyzing qualitative and mixed methods data. To increase enrollment and boost retention for training, flipped and asynchronous online modalities will be emphasized. The Advance-CTR website will be expanded to host educational pages. In addition to continuing support for the Pilot Project Program, Professional Development and Biomedical Informatics, Bioinformatics, and Cyberinfrastructure Enhancement (BIBCE) Core, we will collaborate with the new Community Engagement and Outreach Core to develop strategies to increase community participation in study design and data collection, design studies that properly address the health needs of the community and create results presentations that inform community decision making. To accomplish these goals, we propose the following Specific Aims. Specific Aim 1: Provide easily accessible, multidisciplinary collaborative support for quantitative and qualitative research design, analysis, interpretation, and dissemination that can work seamlessly with and within existing health research structures. Specific Aim 2: Provide training in study design, epidemiology, biostatistics and qualitative and mixed methods to clinical and translational researchers and research staff, delivered in a variety of formats, both synchronous and asynchronous (in-person and remote), using the latest educational methods and technologies. Specific Aim 3: Facilitate the development and widespread dissemination of innovative design and analytic methods and tools for clinical and translational research.

摘要-生物统计学、流行病学和研究设计核心 BERD核心帮助改变了罗得岛的临床和转化研究， Advance-CTR提供研究设计、数据收集、数据分析、结果框架和绘图方面的指导 合理的推论BERD还提供研究原则和各种基本工具的培训。 其结果是，研究申请的质量显著提高， 对年轻研究人员的支持，研究界的高度满意和兴奋，以及 渴望更多的支持。 在第二阶段，BERD核心将扩大其支持到新的领域，使用新的模式， 新的观众我们将努力把许多孤立的分析师群体联系起来， 他们是Advance-CTR合作伙伴中的嵌入式成员。我们的目标是发展可持续的基础设施， 满足了整个国家的研究需求。通过利用伙伴机构的现有资源， 这些努力将有助于最大限度地发挥其现有投资的价值，并指出可以 通过合作或扩展来填充。我们的集中式门户网站已经有效地匹配了调查人员， 一批具有长期咨询经验的高素质和多样化的专家和一批教师 擅长教学的研究领导者。我们将扩大咨询和培训支持，包括增加第二个 核心共同领导，用于设计和分析定性和混合方法数据。为了提高入学率， 将强调通过培训、翻转和异步在线方式提高保留率。先进CTR 网站将扩大到托管教育网页。除了继续支持试点项目外， 专业发展和生物医学信息学，生物信息学和网络基础设施 增强（BIBCE）核心，我们将与新的社区参与和外展核心合作， 制定战略，增加社区参与研究设计和数据收集，设计研究， 适当解决社区的健康需求，并创建告知社区的结果演示文稿 决策。为了实现这些目标，我们提出以下具体目标。 具体目标1：提供易于获得的多学科协作支持， 研究设计，分析，解释和传播，可以与现有的 卫生研究机构。 具体目标2：提供研究设计、流行病学、生物统计学以及定性和混合方法方面的培训 临床和翻译研究人员和研究人员，以各种格式提供，既同步 和异步（面对面和远程），使用最新的教育方法和技术。 具体目标3：促进创新设计和分析的发展和广泛传播 临床和转化研究的方法和工具。