NIDCD Core for Clinical Research and Care

NIDCD 临床研究和护理核心

基本信息

项目摘要

The NIDCD Core for Clinical Research and Care supports the following NIDCD projects: 1 Z01-DC-000016 NF-kappaB in the molecular pathogenesis and therapy of Neoplasms Affecting Human Communication 1 ZIA DC000039 Identification of Genes Causing Syndromic And Nonsyndromic Hearing Impairment 1 ZIA DC000046 Genetic Studies of Human Communications Disorders 1 ZIA DC000060 Molecular Analysis Of Human Hereditary Deafness 1 ZIA DC000064 Clinical Analysis Of Disorders Of Hearing And Balance 1 ZIA-DC-000073 Signal and Transcription Factor Network Interactions in Head and Neck Cancer 1 ZIA-DC-000074 Genomics and Proteomics of Head and Neck Cancer 1 ZIA-DC-000082 Neurotology Program 1 ZIA-DC-000087 Characterization & Enhancement of Anti-tumor Immune Responses in Head & Neck Cancer 1-ZIA-DC-000088 Cellular and Molecular Pathogenesis of Hearing Restoration in Adullt Inner Ear 1-ZIA-DC-000090 Mechanisms and Optimal Combination of Cisplatin Chemotherapy for Head and Neck Cancer The NIDCD and collaborative protocols supported by the core include: OH93-DC-0016 - Nonsyndromic Hereditary Hearing Impairment Gene Mapping: India / Pakistan Protocol 97-DC-0180 - Genetic Analysis of Human Hereditary Hearing Impairment 01-DC-0228 - Clinical and Molecular Analysis of Hearing Impairment with Enlarged Vestibular Aqueducts 01-DC-0229- Genetic Analysis of Hereditary Disorders of Hearing and Balance 17-DC-0138 - Cisplatin and statins in ototoxcity 18-DC-0051 - NIDCD Biospecimens protocol 20-DC-0047 Natural History and Genome Editing in Dominant Hearing Loss 21-DC-0002 Phase III Interventional Study using Atorvastatin to Reduce Cisplatin-Induced Hearing Loss 21-C-0009 A Natural History Study of Children and Adults With Olfactory Neuroblastoma 000077 Clinical Data and Specimens in head and neck disorders 000141 Hearing Instability Phenotyping 15-D-0129 Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 in Irradiation-Induced Parotid Salivary Hypofunction 19-C-0041 Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma 19-C-0002 A Phase II Study of M7824 in Subjects with Recurrent Respiratory Papillomatosis 20-C-0024 Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination with TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated with Human Papillomavirus Infection 20-C-0155 Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetic , Immune and Clinical Activity of SX-682 in Combination with M7824 With CV301 TRICOM in Advanced Solid Tumors 20-C-0104 Phase I/II Trial of HPV Vaccine PRGN-2009 Alone or in Combination with Anti-PD-L1/TGF-Beta Trap (M7824) in Subjects with HPV Positive Cancers 21-C-0013 A Phase I Study of Adjuvant PRGN-2012 in Adult Patients with Recurrent Respiratory Papillomatosis The NIDCD Core for Clinical Research and Care supports over 3,000 outpatient clinic evaluations per year. Core otolaryngologists perform 50-100 major surgical cases annually. Staff mentor medical students during senior clinical clerkships. The Otolaryngologist Surgeon Scientist Career Development Program is coordinated through the OCD.
NIDCD临床研究和护理核心支持以下NIDCD项目: 1 Z01-DC-000016核因子-kappaB在影响人类沟通的肿瘤分子发病机制和治疗中的作用 1 Zia DC000039综合征性和非综合征性耳聋基因鉴定 1 Zia DC000046人类沟通障碍的遗传学研究 1人遗传性耳聋的Zia DC000060分子分析 1 Zia DC000064听力和平衡障碍临床分析 1头颈癌中ZIA-DC-000073信号和转录因子网络的相互作用 1头颈癌ZIA-DC-000074基因组学和蛋白质组学研究 1个ZIA-DC-000082神经病学项目 1-ZIA-DC-000087的特性及其增强头颈癌抗肿瘤免疫应答的研究 1-ZIA-DC-000088成人内耳听力恢复的细胞和分子机制 1-ZIA-DC-000090机制及顺铂治疗头颈癌的优化组合 核心支持的NIDCD和协作协议包括: OH93-DC-0016-非综合征遗传性耳聋基因图谱:印度/巴基斯坦方案 97-DC-0180-遗传性耳聋的遗传分析 01-DC-0228-前庭导水管扩大所致听力障碍的临床和分子分析 01-DC-0229-遗传性听力和平衡障碍的遗传分析 17-DC-0138-顺铂和他汀类药物耳毒性 18-DC-0051-NIDCD生物检疫协议 20-DC-0047遗传性耳聋的自然病史和基因组编辑 21-DC-0002阿托伐他汀降低顺铂所致听力损失的III期干预研究 21-C-0009儿童和成人嗅神经母细胞瘤的自然史研究 000077例头颈部疾病的临床资料和标本 000141听力不稳定表型 15-D-0129剂量递增研究评价单次注射携带人水通道蛋白-1基因的腺相关病毒载体治疗放射性腮腺功能减退的安全性 19-C-0041双适形调强再放疗治疗局部复发的头颈部鳞状细胞癌 19-C-0002复发性呼吸道乳头状瘤病患者M7824的II期研究 20-C-0024抗PD-L1/转化生长因子-β陷阱(M7824)单独及联合三联疫苗和N-803治疗与人乳头瘤病毒感染无关的可切除头颈部鳞状细胞癌 20-C-0155期试验研究SX-682联合M7824和CV301治疗晚期实体瘤的安全性、耐受性、药代动力学、免疫学和临床活性 HPV疫苗PRGN-2009单独或联合抗PD-L1/转化生长因子-β陷阱(M7824)治疗HPV阳性癌症的I/II期20-C-0104试验 21-C-0013佐剂PRGN-2012治疗成人复发性呼吸道乳头状瘤病的I期研究 NIDCD临床研究和护理核心每年支持3000多个门诊评估。耳鼻咽喉科核心医生每年要做50-100例大手术。在高级临床助理期间,工作人员指导医学生。耳鼻喉科外科科学家职业发展计划是通过强迫症协调的。

项目成果

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CARTER VAN WAES其他文献

CARTER VAN WAES的其他文献

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{{ truncateString('CARTER VAN WAES', 18)}}的其他基金

GENE AND IMMUNOTHERAPY OF NEOPLASMS AFFECTING HUMAN COMMUNICATION
影响人类交流的肿瘤基因和免疫治疗
  • 批准号:
    6289632
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
NF-kappaB in pathogenesis and therapy of head and neck cancer
NF-κB 在头颈癌发病机制和治疗中的作用
  • 批准号:
    8349616
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
Molecular Therapy Of Neoplasms Affecting Human Communica
影响人类通讯的肿瘤的分子治疗
  • 批准号:
    6966643
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
Genomics and Proteomics of Head and Neck Cancer
头颈癌的基因组学和蛋白质组学
  • 批准号:
    7967002
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
NF-kappaB in pathogenesis and therapy of head and neck cancer
NF-κB 在头颈癌发病机制和治疗中的作用
  • 批准号:
    8745647
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
NF-kappaB in pathogenesis and therapy of head and neck cancer
NF-κB 在头颈癌发病机制和治疗中的作用
  • 批准号:
    9147422
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
Gene And Immunotherapy Of Neoplasms Affecting Human Comm
影响人类通讯的肿瘤的基因和免疫治疗
  • 批准号:
    6690276
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
Molecular Therapy Of Neoplasms Affecting Human Communication
影响人类交流的肿瘤的分子治疗
  • 批准号:
    7593327
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
NF-kappaB in pathogenesis and therapy of head and neck cancer
NF-κB 在头颈癌发病机制和治疗中的作用
  • 批准号:
    10688908
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
NIDCD Core for Clinical Research and Care
NIDCD 临床研究和护理核心
  • 批准号:
    10249876
  • 财政年份:
  • 资助金额:
    $ 254.1万
  • 项目类别:
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