NIDCD Core for Clinical Research and Care

NIDCD 临床研究和护理核心

• 批准号: 9353170
• 负责人: CARTER VAN WAES
• 金额: $ 130.31万
• 依托单位: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9353170
• 关键词: Administrator; Admission activity; Affect; Ambulatory Care Facilities; Appointment; Area; Attention; Audiology; Auditory; Bibliography; Brain imaging; Care given by nurses; Caring; Chromosome Mapping; Cisplatin; Clinical; Clinical Clerkship; Clinical Investigator; Clinical Research; Clinical Research Protocols; Clinical Services; Clinical Trials; Clinics and Hospitals; Communication; Communication impairment; Complex; Consult; Continuing Education; Credentialing; Data; Data Collection; Databases; Development; Disease; Emergency Situation; Endoscopy; Equilibrium; Equipment and Supplies; Evaluation; Fellowship; Fostering; Genes; Genetic study; Genomics; Head and Neck Cancer; Head and Neck Surgeon; Head and Neck Surgery; Hearing; Hereditary Disease; Hospitals; Hour; Human; Human Resources; Immune response; India; Inherited; Inpatients; Institutes; Institutional Review Boards; Intramural Research Program; Laboratories; Labyrinth; Maintenance; Manuscripts; Measures; Medical; Medical Students; Mentors; Mission; Modeling; Molecular; Molecular Analysis; Monitor; NF-kappa B; National Institute on Deafness and Other Communication Disorders; Neoadjuvant Therapy; Nursing Research; Operative Surgical Procedures; Otolaryngologist; Otolaryngology; Outpatients; Pakistan; Pathogenesis; Patient Care; Patient Education; Patients; Physicians; Pilot Projects; Policies; Process; Proteomics; Protocols documentation; Provider; Publishing; Records; Recruitment Activity; Research; Research Support; Research Training; Resources; Scientist; Services; Signal Transduction; Sirolimus; Speech; Stuttering; Supervision; Surgeon; Taste Perception; Testing; Time; Training; Travel; United States National Institutes of Health; Vestibular Aqueduct; Visit; Voice; career development; chemotherapy; clinical care; data management; deafness; genetic analysis; hearing impairment; human subject; inpatient service; meetings; neoplasm therapy; programs; protocol development; quality assurance; response; restoration; screening; symposium; transcription factor; tumor; volunteer

The NIDCD Core for Clinical Research and Care supports the following NIDCD projects: 1 Z01-DC-000016 NF-kappaB in the molecular pathogenesis and therapy of Neoplasms Affecting Human Communication 1 ZIA DC000039 Identification of Genes Causing Syndromic And Nonsyndromic Hearing Impairment 1 ZIA DC000046 Genetic Studies of Human Communications Disorders 1 ZIA DC000057 Brain Imaging And Modeling 1 ZIA DC000060 Molecular Analysis Of Human Hereditary Deafness 1 ZIA DC000064 Clinical Analysis Of Disorders Of Hearing And Balance 1 ZIA-DC-000073 Signal and Transcription Factor Network Interactions in Head and Neck Cancer 1 ZIA-DC-000074 Genomics and Proteomics of Head and Neck Cancer 1 ZIA-DC-000082 Neurotology Program 1 ZIA-DC-000087 Characterization & Enhancement of Anti-tumor Immune Responses in Head & Neck Cancer 1-ZIA-DC-000088 Cellular and Molecular Pathogenesis of Hearing Restoration in Adullt Inner Ear 1-ZIA-DC-000090 Mechanisms and Optimal Combination of Cisplatin Chemotherapy for Head and Neck Cancer The NIDCD protocols supported by the core include: T-DC-0005 Studies of Measures of Attention Oh93-DC-0016 - Nonsyndromic Hereditary Hearing Impairment Gene Mapping: India / Pakistan Protocol 97-DC-0057 - Non-parametric and parametric Linkage Studies of Stuttering 97-DC-0180 - Genetic Analysis of Human Hereditary Hearing Impairment 00-DC-0073- Identification of Hereditary Auditory Processing Defiicts 01-DC-0099 - Evaluation for NIDCD Head and Neck Surgery Branch Clinical Research Protocols 01-DC-0228 - Clinical and Molecular Analysis of Hearing Impairment Associated with Enlarged Vestibular Aqueducts (EVA) 01-DC-0229- Genetic Analysis of Hereditary Disorders of Hearing and Balance 01-DC-0230 - Studies in the Deficits in the Sense of Taste 10-D-180 - Pilot Study of neoadjuvant rapamycin for patients with advanced head and neck cancer The NIDCD Core for Clinical Research and Care supports over 3,000 outpatient clinic evaluations per year. Core otolaryngologists perform 50-100 major surgical cases annually. Staff mentor medical students during senior clinical clerkships. The Otolaryngolist Surgeon Scientist Career Development Program coordinated through the OCD, recruited two candidates in the past year. Collaborative studies resulted in contributions to several published manuscripts listed in the Bibliography.

NIDCD临床研究和护理核心支持以下NIDCD项目： 1 Z01-DC-000016核因子-kappaB在影响人类沟通的肿瘤分子发病机制和治疗中的作用 1 Zia DC000039综合征性和非综合征性耳聋基因鉴定 1 Zia DC000046人类沟通障碍的遗传学研究 1 Zia DC000057脑成像和建模 1人遗传性耳聋的Zia DC000060分子分析 1 Zia DC000064听力和平衡障碍临床分析 1头颈癌中ZIA-DC-000073信号和转录因子网络的相互作用 1头颈癌ZIA-DC-000074基因组学和蛋白质组学研究 1个ZIA-DC-000082神经病学项目 1-ZIA-DC-000087的特性及其增强头颈癌抗肿瘤免疫应答的研究 1-ZIA-DC-000088成人内耳听力恢复的细胞和分子机制 1-ZIA-DC-000090机制及顺铂治疗头颈癌的优化组合 核心支持的NIDCD协议包括： T-DC-0005注意力测量方法的研究 Oh93-DC-0016-非综合征遗传性耳聋基因图谱：印度/巴基斯坦方案 97-DC-0057-口吃的非参数和参数链接研究 97-DC-0180-遗传性耳聋的遗传分析 00-DC-0073-遗传性听觉处理缺陷的鉴定 01-DC-0099-NIDCD头颈外科分会临床研究方案评价 01-DC-0228-前庭导水管扩大所致听力损害的临床和分子分析 01-DC-0229-遗传性听力和平衡障碍的遗传分析 01-DC-0230-味觉缺陷研究 10-D-180-雷帕霉素治疗晚期头颈癌的先导性研究 NIDCD临床研究和护理核心每年支持3000多个门诊评估。耳鼻咽喉科核心医生每年要做50-100例大手术。在高级临床助理期间，工作人员指导医学生。耳鼻咽喉科医生科学家职业发展计划通过强迫症协调，在过去的一年里招募了两名候选人。 合作研究为书目中列出的几个已发表的手稿做出了贡献。