NIDCD 临床研究和护理核心-猫眼课题宝

NIDCD 临床研究和护理核心

批准号：

10249876

负责人：

CARTER VAN WAES

金额：

$222.91万

依托单位：

NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/10249876

关键词：

Administrator Admission activity Affect Ambulatory Care Facilities Appointment Area Audiology Care given by nurses Caring Chromosome Mapping Cisplatin Clinical Clinical Clerkship Clinical Investigator Clinical Research Clinical Research Protocols Clinical Services Clinical Trials Clinics and Hospitals Communication Communication impairment Complex Consult Continuing Education Credentialing Cryptococcus Data Data Collection Databases Development Disease Emergency Situation Endoscopy Equilibrium Equipment and Supplies Evaluation Fellowship Fostering Genes Genetic study Genomics Head Cancer Head and Neck Cancer Head and Neck Surgeon Head and Neck Surgery Hearing problem Hereditary Disease Hospital Administration Hospitals Hour Human Human Resources India Inpatients Institutes Institutional Review Boards Intramural Research Program Laboratories Labyrinth Maintenance Medical Medical Students Meningoencephalitis Mentors Mission Molecular Molecular Analysis Monitor NF-kappa B National Institute on Deafness and Other Communication Disorders Neck Cancer Nursing Research Operative Surgical Procedures Otolaryngologist Otolaryngology Outpatients Pakistan Pathogenesis Patient Care Patient Education Patients Physicians Policies Program Development Proteomics Protocols documentation Provider Records Reporting Research Research Support Research Training Resources Scientist Services Signal Transduction Speech Supervision Surgeon Syndrome Testing Time Training Travel United States National Institutes of Health Vestibular Aqueduct Visit Voice anti-tumor immune response career development chemotherapy clinical care clinical implementation data management effective therapy genetic analysis genetic deafness hearing impairment hearing restoration hereditary hearing loss human subject inpatient service meetings multidisciplinary neoplasm therapy outpatient programs patient screening precision medicine programs protocol development quality assurance recruit response symposium transcription factor volunteer

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英文摘要

The NIDCD Core for Clinical Research and Care supports the following NIDCD projects: 1 Z01-DC-000016 NF-kappaB in the molecular pathogenesis and therapy of Neoplasms Affecting Human Communication 1 ZIA DC000039 Identification of Genes Causing Syndromic And Nonsyndromic Hearing Impairment 1 ZIA DC000046 Genetic Studies of Human Communications Disorders 1 ZIA DC000060 Molecular Analysis Of Human Hereditary Deafness 1 ZIA DC000064 Clinical Analysis Of Disorders Of Hearing And Balance 1 ZIA-DC-000073 Signal and Transcription Factor Network Interactions in Head and Neck Cancer 1 ZIA-DC-000074 Genomics and Proteomics of Head and Neck Cancer 1 ZIA-DC-000082 Neurotology Program 1 ZIA-DC-000087 Characterization & Enhancement of Anti-tumor Immune Responses in Head & Neck Cancer 1-ZIA-DC-000088 Cellular and Molecular Pathogenesis of Hearing Restoration in Adullt Inner Ear 1-ZIA-DC-000090 Mechanisms and Optimal Combination of Cisplatin Chemotherapy for Head and Neck Cancer The NIDCD protocols supported by the core include: Oh93-DC-0016 - Nonsyndromic Hereditary Hearing Impairment Gene Mapping: India / Pakistan Protocol 97-DC-0180 - Genetic Analysis of Human Hereditary Hearing Impairment 01-DC-0099 - Evaluation for NIDCD Head and Neck Surgery Branch Clinical Research Protocols 01-DC-0228 - Clinical and Molecular Analysis of Hearing Impairment Associated with Enlarged Vestibular Aqueducts (EVA) 01-DC-0229- Genetic Analysis of Hereditary Disorders of Hearing and Balance 17-DC-0138 - Cisplatin and statins in ototoxcity 18-DC-0051 - NIDCD Biospecimens protocol The NIDCD Core for Clinical Research and Care supports over 3,000 outpatient clinic evaluations per year. Core otolaryngologists perform 50-100 major surgical cases annually. Staff mentor medical students during senior clinical clerkships. The Otolaryngolist Surgeon Scientist Career Development Program coordinated through the OCD, recruited two candidates in the past year. Selected Collaborative Reports: Gochuico BR, Ziegler SG, Ten NS, Balanda NJ, Mason CE, Zumbo P, Evans CA, Van Waes C, Gahl WA, Malicdan MCV.A comprehensive, multidisciplinary, precision medicine approach to discover effective therapy for an undiagnosed, progressive, fibroinflammatory disease Transl Res. 2020 Jan;215:31-40. doi: 10.1016/j.trsl.2019.08.008. Epub 2019 Aug 28. King KA, Ansari G, Panackal AA, Zalewski C, Anjum S, Bennett JE, Beri A, Kim HJ, Hammoud D, Brewer CC, Williamson PR. Audiologic and Otologic Complications of Cryptococcal Meningoencephalitis in Non-HIV Previously Healthy Patients. Otol Neurotol. 2019 Jul;40(6):e657-e664. doi: 10.1097/MAO.0000000000002242.

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