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中文摘要
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摘要 降低乳腺癌发病率和死亡率的国家努力的长期成功部分取决于 乳腺癌SPORE计划的能力,以吸引和建立人才的转化研究事业 年轻的教师自1992年以来,美国乳腺癌协会利用职业发展基金促进 选定的研究人员的乳腺癌研究生涯。SPORE职业提升计划 (CEP)两所大学都从外部招聘并确定对转化型乳腺癌研究感兴趣的内部教师。 然后,CEP将初级教师与培训课程和高级导师相匹配。我们力求丰富这一领域 我们努力招募合格的妇女和少数民族作为该方案的参与者和导师。 在该计划的24年里,由CEP资助的招聘人员包括17名女性和6名少数民族教师(3名 非洲裔美国人,三名西班牙裔)。与校园内各部门的联合招聘吸引了杰出的人才 以及它的癌症中心。该孢子CEP使初级教师提供扩展培训, 由受人尊敬和成功的调查人员组成的互动小组,他们可以影响和帮助建立职业生涯。的 一个优秀的人才库和有效的培训和指导计划相结合,导致了精英 乳腺癌研究人员的骨干,他们的工作有助于国家乳腺癌的努力。 在过去六年中,该方案吸引了13名参与者,其中5名是妇女,3名是少数民族。我们 我特别高兴的是,13名新兵中有6名被评为科门职业催化学者(一名 DRP获奖者)和几个已经由NCI资助。这些CEP参与者的贡献包括 发表的研究,资助的赠款和合作的乳腺癌研究在整个人口范围, 基础、临床和转化研究。在CEP计划的过程中,许多参与者 成为领导者。这些人包括开发CBCS的鲍勃·密立根;查尔斯·佩鲁,多PI和合作伙伴, 项目3的负责人;丽莎凯里共同项目负责人和项目1和3的共同负责人以及职业生涯 增强计划; Melissa Troester,项目1的共同负责人; Carey Anders,项目临床试验负责人 #4; Claire Dees项目#2的共同研究者和Katie Hoadley项目#1,#3的共同研究者, 生物信息学/生物统计学核心。 在接下来的五年里,乳腺癌孢子将继续促进和发展的职业生涯, 转化型乳腺癌研究。美国乳腺癌协会要求5万美元支持职业生涯 发展这些资金将与每年40 - 60万美元的机构资金联合收割机结合起来, 翻译乳腺癌研究的教师招聘和职业发展。领导者将 继续确定,招聘和发展少数民族和妇女教师。
英文摘要
Abstract The long-term success of national efforts to reduce breast cancer incidence and mortality rests in part on the ability of Breast Cancer SPORE programs to attract and build the translational research careers of talented young faculty. Since 1992, the UNC Breast Cancer SPORE has used career development funds to promote the breast cancer research careers of selected investigators. The SPORE Career Enhancement Program (CEP) both recruits externally and identifies internal faculty with interest in translational breast cancer research. The CEP then matches junior faculty with training offerings and senior mentors. We seek to enrich the field with our efforts to recruit qualified women and minorities as both participants and mentors in the program. Over the 24 years of the program recruits funded by the CEP include 17 women and six minority faculty (three African Americans, three Hispanic). Co-recruitment with departments across campus attracts exceptional talent to UNC and its Cancer Center. The SPORE CEP makes available extended training for junior faculty with an interactive group of respected and successful investigators who can influence and help build careers. The combination of an excellent talent pool and an effective training and mentoring program has resulted in an elite cadre of breast cancer researchers whose work contributes to the national breast cancer effort. Over the last six years the CEP has attracted 13 participants; five were women and three were minorities. We are particularly pleased that six of the 13 recruits were named Komen Career Catalyst Scholars (as was one DRP Awardee) and several have already been funded by NCI. These CEP participants’ contributions include published research, funded grants and collaborative breast cancer research across the spectrum of population, basic, clinical and translational research. Over the course of the CEP program a number of participants have become SPORE leaders. These include Bob Millikan, who developed CBCS; Charles Perou, Multi-PI and co- leader of Project 3; Lisa Carey Co-program head and co-leader of Projects 1 and 3 and the Career Enhancement Program; Melissa Troester, co-leader of Project 1; Carey Anders, clinical trial leader of Project #4; Claire Dees co-investigator on Project #2 and Katie Hoadley co-investigator Project #1, #3 and the Bioinformatics / Biostatistics Core. Over the next five years, the UNC Breast Cancer SPORE will continue to promote and develop careers in translational breast cancer research. The UNC Breast Cancer SPORE requests $50,000 to support career development. These funds will combine with $400-600,000 yearly in institutional funds to provide for recruitment and career development of faculty in translational breast cancer research. The SPORE leaders will continue to identify, recruit, and develop minority and women faculty.
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Optimizing HER2-targeting using RNA- and DNA-based predictive algorithms
UNC Lead Academic Participating Site
Optimizing HER2-targeting using RNA- and DNA-based predictive algorithms
UNC Lead Academic Participating Site
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