Administrative Core

行政核心

• 批准号: 10469446
• 负责人: ROBERT J VASSAR
• 金额: $ 57.06万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10469446
• 关键词: Adopted; Adoption; Advocate; Alzheimer' s Disease; Animal Welfare; Biological Markers; Caregivers; Chicago; Cities; Clinical Trials; Collaborations; Contracts; Data; Dementia; Development; Education; Ensure; Faculty; Funding; Goals; Health Insurance Portability and Accountability Act; Illinois; Institutional Review Boards; Lead; Leadership; Monitor; Parents; Patients; Policies; Progress Reports; Research; Research Priority; Resource Sharing; Resources; Role; Running; Sampling; Time; Translational Research; United States National Institutes of Health; Universities; Update; beneficiary; cohesion; human subject; innovation; meetings; molecular imaging; operation; ranpirnase; recruit; responsible research conduct

PROJECT SUMMARY - ADMINISTRATIVE CORE The ultimate goal of an Alzheimer's Disease Research Center (ADRC) is to promote innovative research on dementia and its treatments while ensuring that patients and caregivers become the beneficiaries of resultant advances. An effective Administrative Core is essential for transforming these goals into accomplishments. To this end, the Administrative Core of the Northwestern ADRC will be guided by the following goals: 1) Lead the day-to-day running of the ADRC and promote "centerness" so that ADRC components function cohesively and leverage dementia-related activities throughout Northwestern University. 2) Maximize the utilization of ADRC resources to fit local and national priorities. 3) Coordinate the adoption of UDS-3, the FTLD module, new clinical trials, and the increased emphasis on biomarkers, including structural and molecular imaging. 4) Facilitate interactions with NACC, NCRAD, and national consortia such as ADNI and ADCS, the Alzheimer's Association, and relevant agencies within the City of Chicago and State of Illinois. 5) Encourage innovative Development Projects, coordinate their review, and monitor the progress of those that receive ADRC funding. To fulfill these goals, the Administrative Core will oversee the finances of the parent NIA P30 and of additional contracts related to multi-center collaborations and clinical trials. It will be responsible for timely progress reports related to these activities as well as the organization of the yearly Scientific Advisory Board (SAB) meeting. An equally important role will be to ensure that the ADRC as a whole meets all IRB and HIPAA requirements and that it is in compliance with NIH policies for human subjects, animal welfare, scientific integrity, data and sample sharing and financial policy. The Administrative Core is also responsible for coordinating the interactions of the ADRC with NIA, other NIH components, other ADRCs, and relevant agencies at the national, state and local levels. Within Northwestern University, the Administrative Core will advocate the allocation of additional faculty, space and financial resources to dementia research.

项目总结--行政核心 阿尔茨海默病研究中心(ADRC)的最终目标是促进对 痴呆症及其治疗，同时确保患者和照顾者成为结果的受益者 预付款。有效的行政核心对于将这些目标转化为成就至关重要。至 为此，西北ADRC的行政核心将以以下目标为指导： 1)领导ADRC的日常运行，促进“中心化”，使ADRC组件发挥作用 在整个西北大学内凝聚和利用与痴呆症相关的活动。 2)最大限度地利用红十字国际委员会的资源，以适应地方和国家的优先事项。 3)协调采用UDS-3、FTLD模块、新的临床试验，并更加重视 生物标志物，包括结构和分子成像。 4)促进与NACC、NCRAD以及ADNI和ADCS等国家财团的互动， 阿尔茨海默氏症协会，以及芝加哥和伊利诺伊州内的相关机构。 5)鼓励创新发展项目，协调其审查，并监测其进展情况 接受ADRC资助的公司。 为了实现这些目标，行政核心将监督母公司NIA P30和其他 与多中心合作和临床试验相关的合同。它将负责及时取得进展 与这些活动有关的报告以及年度科学咨询委员会的组织情况 开会。同样重要的作用将是确保亚洲发展委员会作为一个整体符合所有IRB和HIPAA 它符合美国国立卫生研究院关于人类受试者、动物福利、科学 诚信、数据和样本共享以及财务政策。行政核心还负责 协调ADRC与NIA、NIH其他部门、其他ADRC和相关机构的互动 国家、州和地方各级的机构。在西北大学内部，行政核心将 倡导为痴呆症研究分配更多的师资、空间和财政资源。