Developmental Research Program

发展研究计划 摘要/描述 MSKCC孢子在软组织中的开发研究计划的目的 肉瘤是支持创新的肉瘤转化研究项目。平移 该计划的研究项目旨在利用动物和人类肉瘤生物学知识 开发和测试与改善诊断、预后和治疗相关的干预措施， 软组织肉瘤患者。该计划将使我们能够快速响应新的 在转化研究的机会，并将帮助我们招募新的科学人才到我们的 孢子，更广泛地说，进入肉瘤相关的研究。的具体目标 发展研究计划是：1）为创新，研究人员提供种子资金- 开始研究肉瘤的生物学、发病机制、进展和自然史，2） 为具有特殊潜力的研究提供资金，以推进该组织的转化研究目标。 孢子。我们每年为这个项目编列40万美元的预算，其中5万美元来自SPORE 奖励自己和35万美元的MSKCC机构和慈善基金。的优先级 将为那些被认为最具创造性和科学质量最高的倡议提供资金。 优先考虑的项目将补充的长期研究目标的SPORE 推进我们的转化研究目标。执行委员会也可以征求和 资助解决MSKCC紧急和特定需求的实验或临床计划 孢子在软组织肉瘤计划或一个独特的研究机会。内部科学 咨询委员会将审查申请，以确定使用这些资金的优先次序， 每年都会选择资助项目。项目可以申请第二年的资助 通过同样的竞争过程，最有前途的项目将是 考虑纳入SPORE作为研究项目，无论是在当前还是未来 融资周期。

Developmental Research Program ABSTRACT/DESCRIPTION The purpose of the Developmental Research Program of the MSKCC SPORE in Soft Tissue Sarcoma is to support innovative translational research projects in sarcoma. The translational research projects in this program aim to use knowledge of animal and human sarcoma biology to develop and test interventions related to improving diagnosis, prognosis, and treatment of patients with soft tissue sarcoma. This program will allow us to respond quickly to new opportunities in translational research and will help us recruit new scientific talent into our SPORE and, more broadly, into sarcoma-relevant research. The specific aims of the Developmental Research Program are: 1) to provide seed funding for innovative, investigator- initiated research in the biology, pathogenesis, progression, and natural history of sarcoma, 2) to fund research with exceptional potential to advance the translational research goals of the SPORE. We are budgeting $400,000 yearly for this program including $50,000 from the SPORE award itself and $350,000 in MSKCC institutional and philanthropic funds. The priority for funding will be those initiatives considered most creative and of the highest scientific quality. Preference will be given to projects that complement the long-term research goals of the SPORE and advance our translational research objectives. The executive committee can also solicit and fund experimental or clinical initiatives that address an urgent and specific need in the MSKCC SPORE in Soft Tissue Sarcoma program or a unique research opportunity. The internal scientific advisory committee will review applications to determine priorities for use of these funds and will annually select projects for funding. Projects may apply for a second year of funding through the same competitive process, and the projects that appear most promising will be considered for incorporation into the SPORE as Research Projects, either in current or future funding cycles.