Center Core Grant for Vision Research

总体情况：项目摘要 奥古斯塔大学/乔治亚医学院的视觉科学小组统称为詹姆斯 和让·卡尔弗视觉发现研究所(卡尔弗VDI)。卡尔弗VDI的使命是参与高 对失明和视力障碍患者的影响研究和发现。在这组人中 基础科学研究人员和眼科医生是22名研究人员，他们指导了15个NEI R01，2个NEI R21和 1 NEI K99。视觉研究中心核心资助金的目标是(1)提供急需的 专业知识和仪器，以加强这些有才华的调查人员的研究计划和(2) 促进团队内部以及与全国各地科学家的合作。为了完成这一使命，我们有 将设施、服务和共享仪器设备组织成以下三个模块：(1)可视化功能 评估；(2)组织学和成像；(3)基因表达/蛋白质组学。这些模块提供研究 资源、服务和共享工具对于多个正在进行的项目的成功至关重要 实验室。对这些模块的支持将促进新项目的开发和加强协作 为我们由NEI资助的研究带来最好的最新技术。奥古斯塔大学致力于愿景 科学和卡尔弗VDI，它于2008年推出。从那时起，该大学一直在支持 招聘11名视觉研究教师，并提供具有竞争力的启动方案和实验室空间 多个系和学院。该大学赞助了与临床相关的试点项目和旅行 奖励受训人员，协助购买尖端仪器，并协助 通过支持强大的研讨会系列、年度务虚会和月度会议进行协作/沟通 小组会议。我们要求以视觉研究中心核心助学金的形式提供支持，以实现 以下目标：目标1.为协助和培训调查员及其工作人员的单元人员提供支助 工作人员在使用复杂的仪器和方法。目标2.借此提供精选服务 提高奥古斯塔大学视觉研究人员的工作效率，避免不必要的重复 设备/努力。目标3.确保杰出的临床相关视力研究的持续生产力 协助：a)由NEI R01资助的成立和首次调查人员，b)由NEI R01资助的成立的调查员 寻求更新NEI资助的项目或开发与视觉相关的新项目的研究人员，c)科学家 来自其他领域的人，他们将自己的科学专长带到视觉研究领域。

Overall: Project Summary The vision science group at Augusta University/Medical College of Georgia is known collectively as the James and Jean Culver Vision Discovery Institute (Culver VDI). The mission of the Culver VDI is to engage in high impact research and discovery for patients suffering from blindness and visual disorders. Within this group of basic science researchers and ophthalmologists are 22 investigators who direct 15 NEI R01s, 2 NEI R21s and 1 NEI K99. The objective of the center core grant for vision research is (1) to provide crucially needed expertise and instrumentation to enhance the research programs of these talented investigators and (2) to promote collaborations within the group and with scientists across the nation. To achieve this mission, we have organized facilities, services and shared instrumentation into the following three modules: (1) Visual Function Assessment; (2) Histology and Imaging; (3) Gene Expression/Proteomics. These modules provide research resources, services and shared instrumentation that are essential to the success of ongoing projects in multiple laboratories. Support of these modules will boost development of new projects and enhance collaborations bringing the best of the latest technology to our NEI-funded research. Augusta University is committed to vision science and to the Culver VDI, which launched in 2008. Since that time, the University has supported recruitment of 11 vision research faculty with competitive start-up packages and laboratory space across multiple departments and colleges. The University has sponsored clinically-relevant pilot projects and travel awards for trainees, assisted with the purchase of sophisticated instrumentation and facilitated collaboration/communication through the support of a robust seminar series, an annual retreat and monthly group meetings. Support is requested in the form of this Center Core Grant for Vision Research to achieve the following aims: Aim 1. To provide support for module personnel who assist and train investigators and their staff in the use of sophisticated instrumentation and methodology. Aim 2. To provide select services thereby enhancing productivity of Augusta University vision researchers and avoiding unnecessary duplication of equipment/effort. Aim 3. To ensure continued productivity of outstanding clinically-relevant vision research by assisting: a) established and first-time NEI R01-funded investigators, b) established NEI R01-funded investigators who seek to renew their NEI-funded projects or develop new vision-related projects, c) scientists from other fields who bring their scientific expertise to the fields of vision research.