Center Core Grant for Vision Research
视觉研究中心核心资助
基本信息
- 批准号:10228010
- 负责人:
- 金额:$ 60.23万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-01 至 2025-08-31
- 项目状态:未结题
- 来源:
- 关键词:Allied Health SciencesAwardBasic ScienceBlindnessCenter Core GrantsClinicalCollaborationsCommunicationCore GrantDentistryDevelopmentDiseaseDoctor of PhilosophyEnsureEquipmentFinancial SupportFundingGene ExpressionGoalsGrantGroup MeetingsHealth SciencesHealthcareHistologyHuman ResourcesImageInfrastructureInstitutesInstitutionInvestigational TherapiesLaboratoriesMethodologyMissionNamesOphthalmologistPatientsPilot ProjectsProductivityProteomicsResearchResearch PersonnelResearch Project GrantsResearch SupportResourcesSchool NursingScientistSeriesServicesTalentsTechnologyTimeTravelUniversitiesVisionVision DisordersVision researchVisual system structureclinically relevantcohortcollegefaculty researchinstrumentationinvestigator trainingmedical schoolsprogramsrecruitsuccessundergraduate studentvision science
项目摘要
Overall: Project Summary
The vision science group at Augusta University/Medical College of Georgia is known collectively as the James
and Jean Culver Vision Discovery Institute (Culver VDI). The mission of the Culver VDI is to engage in high
impact research and discovery for patients suffering from blindness and visual disorders. Within this group of
basic science researchers and ophthalmologists are 22 investigators who direct 15 NEI R01s, 2 NEI R21s and
1 NEI K99. The objective of the center core grant for vision research is (1) to provide crucially needed
expertise and instrumentation to enhance the research programs of these talented investigators and (2) to
promote collaborations within the group and with scientists across the nation. To achieve this mission, we have
organized facilities, services and shared instrumentation into the following three modules: (1) Visual Function
Assessment; (2) Histology and Imaging; (3) Gene Expression/Proteomics. These modules provide research
resources, services and shared instrumentation that are essential to the success of ongoing projects in multiple
laboratories. Support of these modules will boost development of new projects and enhance collaborations
bringing the best of the latest technology to our NEI-funded research. Augusta University is committed to vision
science and to the Culver VDI, which launched in 2008. Since that time, the University has supported
recruitment of 11 vision research faculty with competitive start-up packages and laboratory space across
multiple departments and colleges. The University has sponsored clinically-relevant pilot projects and travel
awards for trainees, assisted with the purchase of sophisticated instrumentation and facilitated
collaboration/communication through the support of a robust seminar series, an annual retreat and monthly
group meetings. Support is requested in the form of this Center Core Grant for Vision Research to achieve the
following aims: Aim 1. To provide support for module personnel who assist and train investigators and their
staff in the use of sophisticated instrumentation and methodology. Aim 2. To provide select services thereby
enhancing productivity of Augusta University vision researchers and avoiding unnecessary duplication of
equipment/effort. Aim 3. To ensure continued productivity of outstanding clinically-relevant vision research by
assisting: a) established and first-time NEI R01-funded investigators, b) established NEI R01-funded
investigators who seek to renew their NEI-funded projects or develop new vision-related projects, c) scientists
from other fields who bring their scientific expertise to the fields of vision research.
总体:项目概要
奥古斯塔大学/佐治亚医学院的视觉科学小组统称为 James
和让·卡尔弗视觉探索研究所 (Culver VDI)。卡尔弗 VDI 的使命是从事高
对失明和视力障碍患者的研究和发现产生影响。在这组人中
基础科学研究人员和眼科医生由 22 名研究人员组成,他们指导 15 个 NEI R01、2 个 NEI R21 和
1 NEI K99。中心视觉研究核心资助的目标是(1)提供急需的
专业知识和仪器,以加强这些才华横溢的研究人员的研究计划,并且(2)
促进小组内部以及与全国各地科学家的合作。为了实现这一使命,我们有
将设施、服务和共享仪器组织成以下三个模块:(1)视觉功能
评估; (2) 组织学和影像学; (3)基因表达/蛋白质组学。这些模块提供研究
资源、服务和共享仪器对于多个领域正在进行的项目的成功至关重要
实验室。对这些模块的支持将促进新项目的开发并加强合作
将最好的最新技术引入我们 NEI 资助的研究中。奥古斯塔大学致力于愿景
科学以及 2008 年推出的 Culver VDI。自那时起,该大学一直支持
招聘 11 名视觉研究人员,提供具有竞争力的启动方案和实验室空间
多个部门和学院。该大学赞助了临床相关的试点项目和旅行
为学员提供奖励,协助购买精密仪器并提供便利
通过一系列研讨会、年度务虚会和每月一次的支持进行协作/沟通
小组会议。请求以该中心视觉研究核心拨款的形式提供支持,以实现
以下目标: 目标 1. 为协助和培训调查员及其人员的模块人员提供支持
工作人员使用先进的仪器和方法。目标 2. 从而提供精选服务
提高奥古斯塔大学视觉研究人员的生产力并避免不必要的重复
设备/努力。目标 3. 确保杰出的临床相关视觉研究的持续生产力
协助:a) 已建立的和首次 NEI R01 资助的研究人员,b) 已建立的 NEI R01 资助的研究人员
寻求更新 NEI 资助项目或开发新的视觉相关项目的研究人员,c) 科学家
来自其他领域的人将他们的科学专业知识带入视觉研究领域。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Sylvia B. Smith其他文献
C57BL/6J-vit/vit mouse model of retinal degeneration: light microscopic analysis and evaluation of rhodopsin levels.
- DOI:
10.1016/0014-4835(92)90017-m - 发表时间:
1992-12 - 期刊:
- 影响因子:3.4
- 作者:
Sylvia B. Smith - 通讯作者:
Sylvia B. Smith
JPET #57109 1 Transport of Amino acid-based Prodrugs by the Na- and Cl- coupled Amino Acid Transporter ATB and Expression of the Transporter in Tissues Amenable for Drug Delivery
JPET
- DOI:
- 发表时间:
2003 - 期刊:
- 影响因子:0
- 作者:
Takahiro;Hatanaka;Masayuki;Haramura;You;Fei;Seiji;Miyauchi;C. Bridges;Preethi S. Ganapathy;Sylvia B. Smith;V. Ganapathy;M. E. Ganapathy - 通讯作者:
M. E. Ganapathy
Regulation of Reduced-Folate Transporter-1 in Retinal Pigment Epithelial Cells by Folate
叶酸对视网膜色素上皮细胞中还原叶酸转运蛋白 1 的调节
- DOI:
10.1080/02713680490894559a - 发表时间:
2005 - 期刊:
- 影响因子:2
- 作者:
Hany Naggar;Tracy K Van Ells;V. Ganapathy;Sylvia B. Smith - 通讯作者:
Sylvia B. Smith
Late-onset cerebellar degeneration in mice induced transplacentally by methylnitrosourea.
甲基亚硝基脲经胎盘诱导小鼠迟发性小脑变性。
- DOI:
10.1002/tcm.1770070503 - 发表时间:
1987 - 期刊:
- 影响因子:0
- 作者:
Sylvia B. Smith;Cathy B. Brown;Mary E. Wright;K. Lemone Yielding - 通讯作者:
K. Lemone Yielding
The Impact of Diabetes on Neuronal, Glial, and Vascular Cells of the Retina
糖尿病对视网膜神经元、胶质细胞和血管细胞的影响
- DOI:
10.1007/978-1-59745-186-4_9 - 发表时间:
2007 - 期刊:
- 影响因子:3.7
- 作者:
Sylvia B. Smith - 通讯作者:
Sylvia B. Smith
Sylvia B. Smith的其他文献
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{{ truncateString('Sylvia B. Smith', 18)}}的其他基金
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