Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers
转移性乳腺癌和前列腺癌的组学和多维空间图谱
基本信息
- 批准号:10471933
- 负责人:
- 金额:$ 30.8万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-09-19 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:AdministratorAdvisory CommitteesAtlasesBenchmarkingBig Data to KnowledgeBiologyClinicalClinical DataClinical TrialsCollaborationsCommunicationCommunitiesComputer softwareConflict (Psychology)DataData AnalysesData Coordinating CenterDevelopmentDisputesEmerging TechnologiesEnsureEvaluationEventFundingGoalsHumanHuman ResourcesImageInformed ConsentInfrastructureInstitutional Review BoardsIntellectual PropertyLeadLeadershipLogisticsMalignant NeoplasmsMalignant neoplasm of prostateMetastatic breast cancerMicroscopyNetwork InfrastructureOffice of Administrative ManagementPoliciesPublicationsQuality ControlReportingResearchResearch PersonnelResolutionResource SharingResourcesReview CommitteeSamplingScientific EvaluationSiteSite VisitSystemSystems BiologyTechnologyThe Cancer Genome AtlasTimeTissuesTrainingUnited States National Institutes of HealthVideoconferencingWorkadjudicateanalytical toolcomputational atlascomputer infrastructuredata accessdata acquisitiondata sharinginstrumentationlight microscopymeetingsmembermultidisciplinarynew technologyprogramsquality assuranceresistance mechanismtechnology developmenttherapy resistanttumoruser-friendlyweb siteworking group
项目摘要
ABSTRACT - Administrative Core
The Administrative Core will serve as the organization, integration, and evaluation hub of the OMS Atlas. This
Core provides leadership, and supports and coordinates: (a) communications and integration within the OMS
Atlas and with the Human Tumor Atlas Network (HTAN); (b) proposal management, reporting, and compliance
activities; (c) oversight of budgetary and intellectual property issues; (d) unit milestone evaluation and
integration, and coordination with the SMMART Clinical Trial; (e) trans-HTAN projects; (f) organization of the
biomedical use case working group; (g) oversight of the OMS Atlas computational infrastructure and the Data
and Resource Sharing Plan; (h) data access and publication plans, including dispute resolution; and (i) HTAN
and External Advisory Committee (EAC) review. The Administrative Core will be led by Dr. Joe Gray (Contact
Program Director/PI, and Characterization Unit Lead); Dr. Gordon Mills (PD/PI, SMMART Clinical Trial
Director, and co-Lead Biospecimen Unit); Dr. Chris Corless (PD/PI and Lead Biospecimen Unit); Dr. Jeremy
Goecks (PD/PI and Lead of the Data Analysis Unit); and Center Administrator, Dr. Heidi Feiler. Drs. Annette
Kolodzie and Brett Johnson will manage integration of the SMMART clinical trial component, and biospecimen
and data sharing, respectively, across the units. This Core will coordinate OMS Atlas participation in the HTAN
programmatic meetings, such as HTAN Steering Committee meetings, annual Investigators meetings and site
visits. For planning and evaluation, it will organize OMS Atlas meetings, including monthly unit progress
meetings and Executive Committee meetings, and quarterly Steering Committee meetings, comprised of all
key personnel. Meetings will be video conferenced to facilitate participation and discussion. In addition, the
Administrative Core will oversee the Data and Resource Sharing Plan and development of the data networking
infrastructure platform in the Analysis Unit that will integrate with the HTAN-Data Coordinating Center (HTAN-
DCC) and the HTAN-Tissue Coordinating Center. The Administrative Core will coordinate publications of
analyses of the OMS data that reveal specific resistance mechanisms. It will oversee trans-HTAN project
development in collaboration with the OMS Atlas EAC and the HTAN. The Administrative Core will organize
annual EAC meetings to provide guidance on OMS Atlas activities. This review will be coordinated with an
annual retreat and HTAN site visit so the external advisors and HTAN leadership will have the opportunity to
interact with researchers from all OMS Atlas sites. To facilitate collaboration, PIs from other HTAN centers, the
HTAN-DCC and leaders of major cancer analysis generating programs (e.g., Cancer Systems Biology
Consortium (CSBC), LINCS, PS-ON, TCGA, ICGC, BD2K, and CTD2) will also be invited. In summary, the
Administrative Core will support and integrate activities between the Clinical Leads, Use Case Biology Leads,
and across the Biospecimen, Characterization and Data Analysis Units, which collectively form the OMS Atlas,
and coordinate these activities with tissue accrual and management through the SMMART Program.
摘要-行政核心
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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JOE W. GRAY其他文献
JOE W. GRAY的其他文献
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{{ truncateString('JOE W. GRAY', 18)}}的其他基金
Understanding the Impact of Microscale and Nanoscale Heterogeneity and Resistance
了解微米级和纳米级异质性和阻力的影响
- 批准号:
10166790 - 财政年份:2020
- 资助金额:
$ 30.8万 - 项目类别:
Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers
转移性乳腺癌和前列腺癌的组学和多维空间图谱
- 批准号:
9788351 - 财政年份:2018
- 资助金额:
$ 30.8万 - 项目类别:
Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers
转移性乳腺癌和前列腺癌的组学和多维空间图谱
- 批准号:
10005913 - 财政年份:2018
- 资助金额:
$ 30.8万 - 项目类别:
Molecular, Cellular, and Tissue Characterization Unit
分子、细胞和组织表征单元
- 批准号:
10471935 - 财政年份:2018
- 资助金额:
$ 30.8万 - 项目类别:
Molecular, Cellular, and Tissue Characterization Unit
分子、细胞和组织表征单元
- 批准号:
10005916 - 财政年份:2018
- 资助金额:
$ 30.8万 - 项目类别:
Molecular, Cellular, and Tissue Characterization Unit
分子、细胞和组织表征单元
- 批准号:
10246896 - 财政年份:2018
- 资助金额:
$ 30.8万 - 项目类别:
Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers
转移性乳腺癌和前列腺癌的组学和多维空间图谱
- 批准号:
10246894 - 财政年份:2018
- 资助金额:
$ 30.8万 - 项目类别:
Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers
转移性乳腺癌和前列腺癌的组学和多维空间图谱
- 批准号:
10005901 - 财政年份:2018
- 资助金额:
$ 30.8万 - 项目类别:
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