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中文摘要
翻译
摘要 管理核心的目的是支持MSKCC的翻译研究目标 以孢子为组织中心,优化孢子之间的协作 MSKCC内外的调查人员。行政核心的具体目标是:(1)提供 有效地组织、管理和协调所有教育、临床和科学活动; 向孢子的所有组成部分提供全面、集中的行政和财政支助: 研究项目、核心、CRP和DEP以及与EAB和IAB的互动;以及,(3)促进有效 与所有主要利益攸关方进行沟通,包括更广泛的科学界 社区、跨机构协作者、NCI、我们的患者权益倡导者(S)和普通公众。这个 管理核心将由医学博士奥马尔·阿卜杜勒-瓦哈布领导,他将监督所有孢子活动。这个 行政核心还包括接受过财务管理、项目管理、赠款 管理、科学和医学编辑、数据管理和行政支持。这些能力 和集中在管理核心的服务提供以下管理和通信 服务于孢子所有组成部分的基础设施: ·科学监督:监测孢子方案翻译研究目标的进展情况, 包括评估个别项目的进展情况,并就 续建/更换项目 ·财务管理:担任中央孢子预算协调员和财务经理 ·编辑服务:为手稿出版和赠款协调提供编辑服务 ·补助金管理:担任国家癌症研究所的行政联络人,确保及时 提交所有要求的报告并遵守机构和联邦法规 ·数据管理系统支持:协助相关核心管理和支持与孢子有关的工作 研究和临床数据库以及维护具有凝聚力和功能的数据共享计划 ·交流:促进我们孢子内部以及与之的交流和合作研究 白血病和更广泛的科学界的其他孢子 ·外展:促进与公众、我们的患者权益倡导者(S)和 更广泛的患者群体,确保孢子临床研究以患者为中心,并 促进平等获得有关孢子研究的治疗 ·会议协调:组织所有与孢子有关的务虚会和会议,并审查正在进行的 孢子研究项目、核心和试点项目以及新试点项目的征集
英文摘要
ABSTRACT The purpose of the Administrative Core is to support the translational research objectives of the MSKCC SPORE in Leukemia by serving as the organizational center, optimizing collaboration among SPORE investigators within and outside MSKCC. The specific aims of the Administrative Core are (1) to provide effective organization, management, and coordination for all educational, clinical, and scientific activities; (2) to provide comprehensive centralized administrative and financial support to all the components of the SPORE: research projects, cores, CRP and DEP as well as interactions with EAB and IAB; and, (3) To foster effective communication with all key stake-holders, both intramural and extramural, including the broader scientific community, cross-institutional collaborators, the NCI, our patient advocate(s) and the general public. The Administration Core will be led by Omar Abdel-Wahab, MD, who will oversee all SPORE activities. The Administrative Core also includes personnel trained in financial management, project management, grants administration, scientific and medical editing, data management, and administrative support. The capabilities and services centralized in the Administrative Core provide the following administrative and communications infrastructure that serve all components of the SPORE: · Scientific Oversight: monitor progress of the translational research objectives of the SPORE program, including evaluating the progress of individual projects and making decisions regarding continuation/replacement projects · Financial Management: serving as the centralized SPORE budgetary coordinator and financial manager · Editorial Services: providing editorial services for manuscript publication and grants coordination · Grants Administration: serve as administrative liaison to the National Cancer Institute, ensuring the timely submission of all required reports and compliance with institutional and federal regulations · Data Management System Support: assist relevant Cores in management and support of SPORE related research and clinical databases as well as maintaining a cohesive and functional data sharing plan · Communication: foster communication and collaborative research within our SPORE as well as with other SPOREs in Leukemia and the wider scientific community · Outreach: foster effective communication with the general public, our patient advocate(s) and, the broader patient community to ensure that SPORE clinical studies are patient-centered and to promote equitable access to treatment on SPORE studies · Meetings Coordination: organize all SPORE related retreats and meetings and review of ongoing SPORE research projects, cores, and pilot projects as well as the solicitation of new pilot project
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Synthetic introns for selective targeting of RNA splicing factor-mutant leukemia
  • 批准号:
    10722782
  • 项目类别:
  • 资助金额:
    $74.86万
  • 财政年份:
    2023
  • 负责人:
    Omar Abdel-Wahab
  • 依托单位:
Charting the differentiation topology of SF3B1 mutated clonal hematopoiesis (CH) and myelodysplastic syndromes (MDS) via a multi-omics single-cell toolkit
Charting the differentiation topology of SF3B1 mutated clonal hematopoiesis (CH) and myelodysplastic syndromes (MDS) via a multi-omics single-cell toolkit
Project 3: Therapeutic inhibition of splicing through inhibition of protein arginine methylation in leukemia
  • 批准号:
    10474285
  • 项目类别:
  • 资助金额:
    $36.77万
  • 财政年份:
    2021
  • 负责人:
    Omar Abdel-Wahab
  • 依托单位:
海外基金